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Atazanavir (Reyataz®)


What is atazanavir?

Atazanavir (Reyataz®) is a capsule that contains medicine used to treat infection caused by the human immunodeficiency virus (HIV). Atazanavir belongs to a group of medicines known as protease inhibitors (PIs). Atazanavir can slow down how soon you will see symptoms of HIV or slow the damage caused by HIV, but it cannot cure HIV infection. Atazanavir is available as a 100 mg, 150 mg, 200 mg, and 300 mg capsule.

Laboratory testing

Atazanavir has the ability to block an enzyme in the body called UGT1A1. UGT1A1 is responsible for removing bilirubin from your body. Bilirubin is made in the body when your red blood cells break down through a natural process. If bilirubin is not removed from your body, your skin and eyes can turn yellow. The medical word for this is “jaundice.” A genetic test can be done to determine how well your UGT1A1 works. If your UGT1A1 works slowly, you should avoid atazanavir because you may become jaundiced. Certain people whose UGT1A1 works slowly may have a condition called Gilbert syndrome. For information about UGT1A1 and how it is affected by atazanavir, talk with your doctor or pharmacist, and see “Do you know… UGT1A1 and medicines.” For more details, go to

How to take atazanavir

  • This tablet is usually taken one (1) time each day.
  • Atazanavir should be taken with food.

Possible side effects of atazanavir

  • Rash
  • Feeling more tired than usual
  • Low blood counts
  • Headache
  • Nausea
  • High blood cholesterol levels
  • High blood glucose levels
  • Increased liver function tests
  • Yellowing of the whites of the eyes

These are the most common side effects, but there may be others. Please report all side effects to the doctor or nurse.

In case of severe side effect or reaction, call the doctor, nurse, or pharmacist at 901-595-3300. If you are outside the Memphis area, dial toll- free 1-866-2STJUDE (1-866-278-5833), and press 0 once the call is connected.

Special instructions for atazanavir

  • Atazanavir capsules should be stored at room temperature and away from heat and moisture.
  • Some side effects, such as low blood counts, can be found with blood tests. So it is very important that you come to clinic at regularly planned times and have blood tests done.


This document is not intended to take the place of the care and attention of your personal physician or other professional medical services. Our aim is to promote active participation in your care and treatment by providing information and education. Questions about individual health concerns or specific treatment options should be discussed with your physician.

St. Jude complies with health care-related federal civil rights laws and does not discriminate on the basis of race, color, national origin, age, disability, or sex.

ATTENTION: If you speak another language, assistance services, free of charge, are available to you. Call 1-866-278-5833 (TTY: 1-901-595-1040).

ATENCIÓN: si habla español, tiene a su disposición servicios gratuitos de asistencia lingüística. Llame al 1-866-278-5833 (TTY: 1-901-595-1040).

تنبيه: إذا كنت تتحدث باللغة العربية فيمكنك الاستعانة بخدمات المساعدة اللغوية المتوفرة لك مجانا. .يرجى الاتصال بالرقم. 5833-278-866-1  (الهاتف النصي: 1040-595-901-1).