Cladribine

What is cladribine?

Cladribine (also known as 2-CDA or Leustatin®) is an anticancer medicine. It is a clear liquid given into a vein (IV).

Cladribine can pose a health hazard to caregivers. All caregivers should take safety precautions while giving this drug. For 48 hours after this drug is given, the patient’s body fluids can contain the drug. During that 48-hour period, caregivers should follow safety guidelines when handling the patient’s vomit, blood, urine, and bowel movements, including diapers. These guidelines include wearing gloves when cleaning up body fluids. For a complete list of safety precautions, see “Do you know… Protecting caregivers from drug hazards.”

Possible side effects of cladribine

Early

• Nausea
• Rash and itching

Later (more than a day after treatment starts)

• Fever
• Lower blood counts 10 to 14 days later
• Decreased kidney and liver function

These are the most common side effects, but there may be others. Please report all side effects to the doctor or nurse.

In case of a severe side effect or reaction, call the doctor, nurse or pharmacist at 595-3300. If you are outside the Memphis area, dial toll-free 1-866-2STJUDE (1-866-278-5833), and press 0 once the call is connected.

Special instructions for cladribine

• It may be easier for you to get infections while you are receiving cladribine. Stay away from crowds and people with colds, flu, or other infections.
• Cladribine can cause nausea and vomiting. The doctor may prescribe medicine to keep you from feeling sick and throwing up after you receive cladribine.