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What is pegfilgrastim?

Pegfilgrastim, also called pegylated granulocyte colony stimulating factor (PEG-GCSF) or Neulasta®, is a long-acting man-made form of a natural human hormone. It is a colorless liquid that is injected under the skin. Pegfilgrastim helps the body make infection-fighting white blood cells, called neutrophils. Some St. Jude patients need this medicine to help build up neutrophils that have been destroyed by chemotherapy.

Possible side effects of pegfilgrastim

  • Mild bone pain
  • Pain/bruising at the injection site

These are the most common side effects, but there may be others. Please report all side effects to the doctor or nurse.

In case of a severe side effect or reaction, call the doctor, nurse, or pharmacist at 595-3300. If you are outside the Memphis area, dial toll-free 1-866-2STJUDE (1-866-278-5833), and press 0 once the call is connected.

Special instructions for pegfilgrastim

  • You will receive one (1) injection 24 hours after your last dose of chemotherapy. A nurse will give you the medicine either in an inpatient room or in the Medicine Room.


This document is not intended to take the place of the care and attention of your personal physician or other professional medical services. Our aim is to promote active participation in your care and treatment by providing information and education. Questions about individual health concerns or specific treatment options should be discussed with your physician.

St. Jude complies with health care-related federal civil rights laws and does not discriminate on the basis of race, color, national origin, age, disability, or sex.

ATTENTION: If you speak another language, assistance services, free of charge, are available to you. Call 1-866-278-5833 (TTY: 1-901-595-1040).

ATENCIÓN: si habla español, tiene a su disposición servicios gratuitos de asistencia lingüística. Llame al 1-866-278-5833 (TTY: 1-901-595-1040).

تنبيه: إذا كنت تتحدث باللغة العربية فيمكنك الاستعانة بخدمات المساعدة اللغوية المتوفرة لك مجانا. .يرجى الاتصال بالرقم. 5833-278-866-1  (الهاتف النصي: 1040-595-901-1).