Skip to main content


WinRho® treatment for ITP


What is WinRho®?

WinRho® is a medicine used to treat immune thrombocytopenia. If your child has immune thrombocytopenia (ITP) and a positive blood type (such as O+, A+, B+, or AB+), he might get WinRho®.

How does WinRho® work?

In people with ITP, the spleen destroys platelets because they are coated with antibodies. Platelets are a type of blood cells that help keep the body from bleeding too much. Antibodies are a type of protein.

WinRho® contains antibodies that bind to red blood cells of people with a positive blood type. When this happens, the spleen destroys some of the red blood cells instead of platelets. This lets more platelets stay in the blood. When this happens, your child’s platelet count goes up.

Destroying the red blood cells is generally not harmful. Your child’s body naturally makes more.

When is WinRho® used?

Your child might get WinRho® if he has:

  • ITP and bleeding symptoms, or
  • Very low platelet counts that put him at high risk of bleeding.

To get WinRho®, your child must have a positive blood type. He must not be anemic (have a low red blood cell count).

How is WinRho® given?

WinRho® is given into a vein (IV). This takes 3 to 5 minutes. The St. Jude staff will watch your child for any side effects for 2 hours after giving the WinRho®

What side effects can WinRho® cause?

Possible side effects

  • Fever
  • Chills
  • Muscle pain
  • Headache
  • Nausea and vomiting
  • Dark urine

Before giving WinRho®, the St. Jude staff will give your child other medicines, such as acetaminophen (Tylenol®) or diphenhydramine (Benadryl®), to help decrease the side effects of WinRho®. St. Jude staff will also give your child medicines to take at home to decrease side effects. 


If you have questions, talk to your child’s doctor or nurse. To learn more about WinRho®, call the St. Jude Hematology Clinic at 901-595-5041. If you have an urgent need after hours or on weekends or holidays, please call the main St. Jude number at 901-595-3300 and ask to speak to the hematologist on call. If you are outside Memphis, dial toll-free 1-866-2STJUDE (1-866-278-5833).  


This document is not intended to take the place of the care and attention of your personal physician or other professional medical services. Our aim is to promote active participation in your care and treatment by providing information and education. Questions about individual health concerns or specific treatment options should be discussed with your physician.

St. Jude complies with health care-related federal civil rights laws and does not discriminate on the basis of race, color, national origin, age, disability, or sex.

ATTENTION: If you speak another language, assistance services, free of charge, are available to you. Call 1-866-278-5833 (TTY: 1-901-595-1040).

ATENCIÓN: si habla español, tiene a su disposición servicios gratuitos de asistencia lingüística. Llame al 1-866-278-5833 (TTY: 1-901-595-1040).

تنبيه: إذا كنت تتحدث باللغة العربية فيمكنك الاستعانة بخدمات المساعدة اللغوية المتوفرة لك مجانا. .يرجى الاتصال بالرقم. 5833-278-866-1  (الهاتف النصي: 1040-595-901-1).