Karen Wright, MD
Karen D. Wright, MD

Karen D. Wright, MD

Assistant Member, St. Jude Faculty

Departments

Divisions

Education

MD – Temple University School of Medicine, Philadelphia, Pennsylvania (2003)
MS – Lehigh University, Bethlehem, Pennsylvania (1999)

Clinical Interests

  • Ependymoma
  • Atypical Teratoid Rhabdoid Tumors
  • Infant brain tumors

Research Interests

  • Cancer genomics
  • Pharmacokinetics in infants
  • New chemotherapeutic agents
  • Developmental neurobiology

Selected Publications

Wright KD, Gajjar A. Current treatment options for pediatric and adult ependymoma. Curr Treat Options Oncol 13(4):465-477, 2012. PMID: 22798016.

Palmer SL, Glass JO, Li Y, Ogg R, Qaddoumi I, Armstrong GT, Wright K, Wetmore C, Broniscer A, Gajjar A, Reddick WE. White matter integrity is associated with cognitive processing in patients treated for a posterior fossa brain tumor. Neuro Oncol 14(9):1185-1193, 2012. PMID: 22898373.

Perko R, Harreld JH, Helton KJ, Sabin ND, Haidar CE, Wright KD. What goes around comes around? Wernicke encephalopathy and the nationwide shortage of intravenous multivitamins revisited. J Clin Oncol 30(31):e318-320, 2012. PMID: 23008290.

Sabin ND, Merchant TE, Harreld JH, Patay Z, Klimo P, Qaddoumi I, Armstong GT, Wright K, Gray J, Indelicato DJ, Gajjar A. Imaging changes in very young children with brain tumors treated with proton therapy and chemotherapy. AJNR 2012. PMID: 22821924.

Murphy ES, Merchant TE, Wu S, Xiong X, Lukose R, Wright KD, Qaddoumi I, Armstrong GT, Broniscer A, Gajjar A. Necrosis after craniospinal irradiation: results from a prospective series of children with central nervous system embryonal tumors. Int J Radiat Oncol Biol Phys 83(5):e655-660, 2012. PMID: 22768993.

Godfraind C, Kaczmarska JM, Kocak M, Dalton J, Wright KD, Sanford RA, Boop FA, Gajjar A, Merchant TE, Ellison DW. Distinct disease-risk groups in pediatric supratentorial and posterior fossa ependymomas. Acta Neuropathol 124(2):247-257, 2012. PMID: 22526017.

Qaddoumi I, Sane M, Li S, Kocak M, Pai-Panandiker A, Harreld J, Klimo P, Wright K, Broniscer A, Gajjar A. Diagnostic utility and correlation of tumor markers in the serum and cerebrospinal fluid of children with intracranial germ cell tumors. Childs Nerv Syst 28(7):1017-1024, 2012. PMID: 22547227.

Wright KD, von der Embse K, Coleman J, Patay Z, Ellison DW, Gajjar A. Isochromosome 17q, MYC amplification and large cell/anaplastic phenotype in a case of medullomyoblastoma with extracranial metastases. Pediatr Blood Cancer 59(3):561-564, 2012. PMID: 22147345.

Atkinson JM, Shelat AA, Carcaboso AM, Kranenburg TA, Arnold LA, Boulos N, Wright KD, Johnson RA, Poppleton H, Mohankumar KM, Feau C, Phoenix T, Gibson P, Zhu L, Tong Y, Eden C, Ellison DW, Priebe W, Koul D, Yung WK, Gajjar A, Stewart CF, Guy RK, Gilbertson RJ. An integrated in vitro and in vivo high throughput screen identifies treatment leads for ependymoma. Cancer Cell 20(3):384-399, 2011. PMCID: PMC3172881.

Pai-Panandiker AS, Merchant TE, Beltran C, Wu S, Sharma S, Boop FA, Jenkins JJ, Helton KJ,Wright KD, Broniscer A, Kun LE, Gajjar A. Sequencing of local therapy affects the pattern of treatment failure and survival in children with atypical teratoid rhabdoid tumors of the central nervous system. Int J Radiat Oncol Biol Phys 82(5):1756-1763, 2011. PMID: 21601374.

Pounds S, Gao CL, Johnson RA, Wright KD, Poppleton H, Finkelstein D, Leary SES, Gilbertson RJ. A procedure to statistically evaluate agreement of differential expression for cross-species genomics.Bioinformatics 82(5):1756-1763, 2011. PMID: 21601374.

Van Poppel M, Klimo P, Jr, Dewire M, Sanford RA, Boop F, Broniscer A, Wright KD, Gajjar A. Resection of infantile brain tumors after neoadjuvant chemotherapy: the St. Jude experience. J Neurosurg Pediatr 8(3):251-256, 2011. PMID: 21882915.

Qaddoumi I, Carey SS, Conklin H, Jenkins J, Sabin N, Boop F, Pai-Panandiker A, Baker JN, Wright K, Broniscer A, Gajjar A. Characterization, treatment, and outcome of intracranial neoplasms in the first 120 days of life. J Child Neurol May 3, 2011.

Johnson R, Wright K, Poppleton H, Murugesan M, Finkelstein D, Rand V, Leary S, White E, Eden C, Hogg  T, Pounds S, Northcott P, Mack S, Neale G, Coyle B, Atkinson J, Dewire M, Gillespie Y, Allen J, Boop FA, Sanford RA, Gajjar A, Ellison DW, Taylor MD, Grundy R, Gilbertson RJ. Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature 466(7306):632-6, 2010.

Wright KD, Qaddoumi I, Patay Z, Gajjar A, Wilson MW, Rodriguez-Galindo C. Successful treatment of early detected trilateral retinoblastoma using standard infant brain tumor therapy. Pediatr Blood Cancer Sep;55(3):570-572, 2010.

Wright KD, Gilbertson RJ. To infinium, and beyond! Cancer Cell May;17(5):419-420, 2010.

Wright KD, Gajjar A. High-dose chemotherapy with autologous stem-cell rescue in children with high-risk brain tumors: controversies and questions [Article #0030]. ASCO Educational Book, 2010.

Wright KD, Gajjar A. New chemotherapy strategies and biological agents in the treatment of childhood ependymoma. Childs Nerv Syst Oct;25(10):1275-82, 2009.

Wright KD, Green DM and Daw NC. Late effects of treatment for Wilms tumor. Pediatr Hematol Oncol Sept;26(6):407-13, 2009.

Johnson R, Wright KD, Gilbertson RJ. Molecular profiling of pediatric brain tumors: insight into biology and treatment. Curr Oncol Rep Jan;11(1):68-72, 2009.

Plotinsky RN, Talbot EA, Kellenberg JE, Reef SE, Buseman SK, Wright KD, Modlin JF. Congenital rubella syndrome in a child born to Liberian refugees: clinical and public health perspectives. Clinical Pediatrics (Phila) May;46(4):349-55, 2007.

Wright K, Ullrich C, Scott A, Brugnara C, Bernstein H. Diagnosis of Iron Deficiency in Children: Reticulocyte Hemoglobin Content. Tarrytown: Bayer HealthCare LLC; 2006.

Scott A, Wright K, Ullrich C, Brugnara C, Bernstein H. Iron Deficiency in Infants and Toddlers. Tarrytown: Bayer HealthCare LLC; 2006.

Benjamin Wright and Karen Wright with Boaz Hus. Ezekiel’s Tomb in Jewish Tradition. The Apocryphal Ezekiel.  Ed. Michael E. Stone, Benjamin G. Wright, David Satran. Georgia: Society of Biblical Literature; pp130-136, 2000.

Last update: February 2013