St. Jude Children's Research Hospital

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Finding Cures. Saving Children.

Inside

Finding the Cures

Elaine Tuomanen, MD and Dr. Jason Rosch, MD

Cholesterol-lowering drug shows promise against serious infections in sickle cell disease

New research suggests a family of widely used cholesterol-lowering drugs might help protect individuals from serious illness following bacterial infection, including the pneumococcal infections that pose a deadly threat to those with sickle cell disease.

Basic Science

The diverse research at St. Jude ranges from discovery-focused and hypothesis-testing laboratory studies to clinical trials of specific agents, regimens, or therapeutic interventions. We continually seek to translate knowledge acquired through basic research into novel approaches for clinical diagnosis and treatment. At the same time, our clinical and laboratory-based investigators use the challenges encountered in the clinic to focus the efforts of our research.

The Research Behind the Cures

Researchers identify new protein with key role in antibody assembly

St. Jude investigators identified a new protein at work inside infection-fighting plasma cells that plays a critical role in quality control during antibody production.

Scientific Report

Key research activities and publications by the investigators at St. Jude during 2008 are summarized in the Scientific Report 2009.

In the News

St. Jude Children’s Research Hospital and Washington University team to unravel genetic basis of childhood cancers

St. Jude Children’s Research Hospital and Washington University School of Medicine in St. Louis, today announced an unprecedented effort to identify the genetic changes that give rise to some of the world’s deadliest childhood cancers. The team has joined forces to decode the genomes of more than 600 childhood cancer patients who have contributed tumor samples for this historic effort.

Interactive / Multimedia

Interactive: Multimedia Presentations
Interactive: Discover St. Jude