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Science & medicine news
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International collaboration helps refine treatment for childhood leukemia
Vincristine and dexamethasone pulses can be safely eliminated from low-risk acute lymphoblastic leukemia treatment.
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Comprehensive clinical sequencing opens door to the promise of precision medicine
St. Jude Children’s Research Hospital study highlights the power of comprehensive whole genome, whole exome and RNA sequencing to better understand and treat each patient’s cancer.
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Research illuminates earliest part of phase separation
St. Jude scientists study how phase separation begins on a microsecond time scale, showing how the earliest events with individual molecules impact assembly speed.
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Chemotherapy can induce mutations that lead to pediatric leukemia relapse
A collaboration led by St. Jude Children’s Research Hospital, Shanghai Children’s Medical Center and others revealed how thiopurines produce mutations that lead to multi-drug resistant leukemia and relapse.
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Molecular groups give context to clinical results
St. Jude scientists looked at tumor samples from a Children’s Oncology Group clinical trial and assigned participants to molecular groups. The findings changed how the trial’s results were interpreted.
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Scientists link frailty and neurocognitive decline in childhood cancer survivors
St. Jude Children’s Research Hospital scientists have shown that frailty contributes to neurocognitive decline in young adult survivors of childhood cancer.