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Science & medicine news
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Chemotherapy sometimes sets the stage for drug-resistant leukemia at relapse
An International collaboration has identified therapy-induced, drug-resistance mutations in children with acute lymphoblastic leukemia who relapse.
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Treating the TOTAL patient: clinical trial reduces relapse
Researchers at St. Jude have announced results of the Total Therapy Study 16 clinical trial, which tested strategies for lowering the rate of relapse of acute lymphoblastic leukemia in children from 2007–2017.
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Controlling the immune system’s brakes to treat cancer, autoimmune disorders
St. Jude researchers have discovered two enzymes that may have a crucial role in treating autoimmune disorders and certain cancers.
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Exercise may give the brain a boost
A St. Jude study reveals more about the link between cancer survivors’ physical fitness and their thinking and learning skills.
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Childhood cancer survivorship data portal in St. Jude Cloud launched at ASHG
A St. Jude Children’s Research Hospital online portal into pediatric cancer survivorship data debuts at the American Society of Human Genetics annual meeting.
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Pharmacogenetics of thiopurine and NUDT15 mutations presented at ASHG
Researchers have uncovered a relationship between the gene NUDT15 and how thiopurine drugs function. These findings support the use of NUDT15 to guide thiopurine dose to limit treatment related toxicity.