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Science & medicine news
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ZBP1 links interferon treatment and dangerous inflammatory cell death during COVID-19
St. Jude scientists identified ZBP1 as a key contributor to the inflammatory cell death that drives morbidity and mortality in COVID-19 patients.
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Updates on gene therapy for ‘bubble boy’ disease and cellular immunotherapy at ASGCT
St. Jude scientists will discuss research on cellular therapies for pediatric cancer and more at the annual meeting.
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A tool to unlock the ‘numbers game’ of big data in rare disease research
Big data can cause big problems in rare disease genetics research. Scientists at St. Jude created a systematic solution to find the inherited genes contributing to rare disease.
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Strategy overcomes EZH2 inhibitor resistance in SMARCB1 mutated cancer
Findings from St. Jude demonstrate the role of chromatin regulation in cancer’s resistance to EZH2 inhibitors and offer a way to make treatment more effective.
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Scientists reveal new cause of cancer
The team looked at a poorly understood form of chronic leukemia, CLPD-NK. The results led the researchers to create a new model of cancer development.
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Study shows how a potential new class of antibiotics works
Scientists at St. Jude are studying antimicrobial compounds called argyrins. Argyrins have shown some success against a bacterium called Pseudomonas aeruginosa.