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Science & medicine news
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Discovery offers potential for stripping tumors of T cell protection
St. Jude has discovered a mechanism that tumors use to switch on protective regulatory T cells, raising the potential for drug treatments that render tumors more vulnerable to cancer immunotherapy.
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IARC and St. Jude announce partnership to expand global pediatric cancer registries
The project will expand and enhance data collection in low- and middle-income countries to support the global push to advance childhood cancer survival.
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Study reveals mutations that drive therapy-related myeloid neoplasms in children
Research from scientists at St. Jude Children’s Research Hospital found mutations up to two years before cancer developed, showing an opportunity for early interventions.
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Lockdowns, border closures and related measures could help stop future pandemics
New Zealand’s experience during the first wave of COVID-19 suggests nonpharmaceutical interventions should be considered to control severe viral respiratory outbreaks in the future.
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Novel CAR-T cell receptor shows early promise for treatment of solid tumors
St. Jude Children’s Research Hospital scientists have created a CAR-T cell receptor designed to improve the effectiveness of immunotherapy for treatment of solid tumors.
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From the clinic to the lab, understanding medulloblastoma relies on molecular profiling
A pair of research papers from St. Jude report on a medulloblastoma clinical trial that provides insights to guide treatment and shed light on relapsed disease.