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Science & medicine news
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Genetic ancestry provides important context for understanding global diversity in childhood leukemia
St. Jude scientists show that addressing racial disparities in acute lymphoblastic leukemia should include considering how genetic ancestry affects biology and prognosis.
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Common cold coronaviruses hinder antibody immune response to SARS-CoV-2 infection
St. Jude study also suggests that prior immunity to common cold coronaviruses does not protect against SARS-CoV-2 infection.
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Modular super-enhancer controls retinal development
Scientists at St. Jude identified distinct functions for regions of a super-enhancer that controls gene expression during retina formation, calling it a ‘modular’ super-enhancer.
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Understanding how autoactivation triggers cell death
Scientists from St. Jude have captured the structure of autoactivated BAK, a key protein for triggering apoptosis in cancer cells.
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Secrets of regulatory T cell development reveal clinical possibilities
St. Jude scientists have identified key steps in production of the regulatory T cells that have a role in everything from autoimmune disorders to cancer.
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SARS-CoV-2 vaccination creates a strong, persistent T-cell response
St. Jude Immunology study details how T cells respond to mRNA vaccination for SARS-CoV-2. Published in Cell, in collaboration with Washington University St. Louis.