Science & medicine news
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Damon Runyon launches new pediatric cancer fellowship in partnership with St. Jude Children’s Research Hospital
$9 million initiative addresses shortage of top young scientists entering pediatric cancer research careers.
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St. Jude finds NLRP12 as a new drug target for infection, inflammation and hemolytic diseases
NLRP12 bridges hemolysis, inflammation and multi-organ damage. Learn how this ‘on’ switch for innate immune cell death could be a drug target to prevent pathology.
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Genetic change increased bird flu severity during U.S. spread
Find how H5N1 avian influenza viruses increased disease-causing abilities & gained the capability to enter mammalian brains as they spread west across North America.
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SWI/SNF complexes “bookmark” cell identity during division
Read about how Scientists at St. Jude determined how the SWI/SNF chromatin remodeling complex helps cancer cells remember how to be cancerous after division.
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Epigenetic landscape modulates pioneer transcription factor binding
St. Jude scientists are studying how pioneer transcription factors access tightly wound DNA. Learn about how their findings may impact therapeutic development.
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Capturing transporter structure paves the way for drug development
Learn how St. Jude scientists captured six new structures of the Spns2 transporter, providing insights to aid therapeutic design for cancer and other diseases.