Gregory T. Armstrong, MD, MSCE
Gregory T. Armstrong, MD, MSCE

Gregory T. Armstrong, MD, MSCE

Associate Member, St. Jude Faculty

Departments

Divisions

Education

BS – Samford University (1995)
MD – University of Alabama School of Medicine (1999)
MS – University of Pennsylvania (Clinical Epidemiology) (2006)

Clinical Interests

  • Cancer survivorship
  • Outcomes research
  • Neuro-oncology

Current Research

  • Childhood Cancer Survivor Study (CCSS), Principal Investigator
  • Longitudinal Cardiotoxicity in Adult Survivors of Childhood Cancer (R01, NIH), Principal Investigator
  • Establishment of a Lifetime Cohort of Adults Surviving Childhood Cancer (SJLIFE)
    • SJLIFE1: Cardiac MRI for Assessment of Cardiomyopathy Following High-Dose (>350mg/m2) Anthracycline Administration for Childhood Malignancy in Asymptomatic Patients (XPD07-076, SJLIF1), Principal Investigator
    • SJLIFE2: Cardiac MRI for Assessment of Cardiomyopathy Following High-Dose (<150mg/m2 Doxorubicin) Anthracycline Administration for Childhood Malignancy in Asymptomatic Patients (XPD07-077, SJLIF2), Principal Investigator
    • SJLIFE3: Observation of Myocardial Injury Secondary to Anthracycline Chemotherapy Evidenced by Delayed Contrast Enhancement on Cardiac MRI (XPD07-078, SJLIF3), Principal Investigator
  • Encouraging Mammography and Preventive Opportunities for Women Exposed to Radiation, Co-Investigator
  • Reducing Skin Cancer in Childhood Cancer Survivors, Co-Investigator
  • Adult Neurobehavioral Late Effects of Pediatric Low Grade Brain Tumors, Co-Investigator

Selected Publications

Gawade PL, Oeffinger KC, Sklar CA, Krull KR, Chemaitilly W, Stovall M, Leisenring W, Armstrong GT, Robison LL, Ness KK. Lifestyle, distress, and pregnancy outcomes in the Childhood Cancer Survivor Study cohort. Am J Obstet Gynecol 212(1):47.e1-47, 2015.

Chow EJ, Chen Y, Kremer LC, Breslow N, Hudson MM, Armstrong GT, Border WL, Feijen EAM, Green DM, Meacham LR, Meeske KA, Mulrooney DA, Ness KK, Oeffinger KC, Sklar CA, Stovall M, van der Pal HJ, Weather RE, Robison LL, Yasui Y.  Individual prediction of heart failure among childhood cancer survivors. J Clin Oncol 33(5): 394-402, 2015.

Ness KK, Armstrong GT, Kundu M, Wilson CL, Tchknoia T, Kirkland JL.  Frailty in childhood cancer survivors. Cancer 65(6): 584-585, 2015.

Mertens AC, Yong J, Dietz A, Kreiter E, Yasui Y, Bleyer A, Armstrong GT, Robison LL, Wasilewski-Masker K. Conditional Survival in Pediatric Malignancies: Analysis of Data from the Childhood Cancer Survivor Study and the Surveillance, Epidemiology and End Results Program. Cancer 121(7): 1108-1117, 2015.

Chemaitilly W, Li Z, Huang S, Ness KK, Clark KL, Green DM, Barnes N, Armstrong GT, Krasin MJ, Srivastava DK, Pui CH, Merchant TE, Kun LE, Gajjar A, Hudson MM, Robison LL, Sklar CA.  Anterior Hypopituitarism in Adult Survivors of Childhood Cancers Treated with Cranial Radiotherapy:  A Report from the St. Jude Lifetime Cohort Study. J Clin Oncol 33(5): 492-500, 2015.

Park ER, Kirchhoff AC, Perez GK, Leisenring W, Weissman JS, Donelan K, Mertens AC, Reschovsky JD, Armstrong GT, Robison LL, Franklin M, Hyland K, Diller LR, Recklitis CJ, Kuhlthau KA.  Childhood Cancer Survivor Study Participants’ Perceptions and Understanding of the Affordable Care Act. J Clin Oncol 33(7): 764-772, 2015.

Dong H, Robison LL, Leisenring WM, Martin LJ, Armstrong GT, Yasui Y.  Estimating the Burden of Recurrent Events in the Presence of Competing Risks: The Method of Mean Cumulative Count. Am J Epidemiol 181(7): 532-540, 2015.

Daniel CL, Armstrong GT, Keske RR, Davine JA, McDonald AJ, Sprunck-Harrild KM, Coleman C, Haneuse SJ, Mertens AC, Emmons KM, Marghoob AA, Elkin EB, Dusza SW, Robison LL, Geller AC.  Advancing survivors’ knowledge (ASK) about skin cancer study: study protocol for a randomized controlled trial. Trials 16:109, 2015.

Phillips SM, Padgett L, Leisenring WM, Stratton KK, Bishop K, Krull KR, Alfano CM, Gibson TM, de Moor JS, Hartigan DB, Armstrong GT, Robison LL, Rowland JH, Oeffinger KC, Mariotto AB. Survivors of childhood cancer in the United States: Prevalence and burden of morbidity. Cancer Epidemiol Biomarkers Prev 24(4):653-63, 2015

Kirchhoff AC, Parsons HM, Kuhthau KA, Leisenring W, Donelan K, Warner EL, Armstrong GT, Robison LL, Oeffinger KC, Park ER. Supplemental Security Income and Social Security Disability Insurance coverage among long-term childhood cancer survivors. J Natl Cancer Inst 107(6):djv057, 2015.

Casillas J, Oeffinger KC, Hudson MM, Greenberg ML, Yeazel MW, Ness KK, Henderson TO, Robison LL, Armstrong GT, Liu Q, Leisenring WM, Yasui Y, Nathan PC.  Identifying Predictors of Longitudinal Decline in the Level of Medical Care Received by Adult Survivors of Childhood Cancer: A Report from the Childhood Cancer Survivor Study. Health Serv Res Epub January 20, 2015.

Daniel CL, Kohler C, Stratton K, Oeffinger KC, Leisenring WM, Whelan K, Armstrong GT, Henderson T, Krull K, Robison LL, Nathan PC.  Predictors of colorectal cancer surveillance among radiation-treated survivors of childhood cancer.  A report from the Childhood Cancer Survivor Study. Cancer 121(11): 1856-63, 2015.

Karlage RE, Wilson CL, Zhang N, Kaste SC, Green DM, Armstrong GT, Robison LL, Chemaitilly W, Srivastava K, Hudson MM, Ness KK.  Validity of anthropometric measurements to characterize obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort Study. Cancer 121(12):2036-43, 2015.

Huang TT, Chen Y, Dietz AC, Yasui Y, Donaldson SS, Stokes DC, Stovall M, Leisenring WM, Sklar CA, Diller LR, Mertens AC, Armstrong GT, Green DM, Robison LL, Ness KK. Pulmonary outcomes in survivors of childhood central nervous system malignancies: A report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer 61(2): 319-325, 2014.

Gramatges MM. Liu Q, Yasui Y, Okcu MF, Neglia JP, Strong LC, Armstrong GT, Robison LL, Bhatia S.  Telomore content and risk of second malignant neoplasm in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Clin Cancer Res 20(4): 904-911, 2014.

Palmer SL, Leigh L, Ellison S, Onar-Thomas A, Wu S, Qaddoumi I, Armstrong GT, Wright K, Wetmore C, Broniscer A, Gajjar A.  Feasibility and efficacy of a computer-based intervention aimed at preventing reading decoding deficits among children undergoing active treatment for medulloblastoma: Results of a randomized trial. J Pediatr Psychol 39(4): 450-458, 2014.

Gurney JG, Bass JK, Onar-Thomas A, Huang J, Chintagumpala M, Bouffet E, Hassall T, Gururangan D, Heath JA, Kellie S, Cohn R, Fisher MJ, Panadiker AP, Merchant TW, Srinivasan A, Wetmore C, Qaddoumi I, Stewart CF, Armstrong GT, Broniscer A, Gajjar A.  Evaluation of amifostine for protection against cisplatin-induced serious hearing loss in children treated for average risk or high risk medulloblastoma. Neuro-Oncol 16(6): 848-855, 2014.

Sabin ND, Santucci AK, Klimo P Jr, Hudson MM, Srivastava D, Zhang N, Kun LE, Krasin MJ, Pui CH, Patay Z, Reddick WE, Ogg RJ, Hillenbrand CM, Robison LL, Krull KR, Armstrong GT.  Incidental detection of late subsequent intracranial neoplasms with magnetic resonance imaging among adult survivors of childhood cancer. J Cancer Surviv 8(3): 329-335, 2014.

Patterson BC, Chen Y, Sklar CA, Neglia J, Yasui Y, Mertens A, Armstrong GT, Meadows A, Stovall M, Robison LL, Meacham L.  Growth hormone exposure as a risk factor for the development of subsequent neoplasms of the central nervous system: A report from the Childhood Cancer Survivor Study. J Clin Endocrinol Metab 99(6): 2030-2037, 2014.

Armstrong GT, Kawashima T, Leisenring W, Stratton K, Stovall M, Hudson MM, Sklar CA, Robison LL, Oeffinger KC.  Aging and risk of severe, disabling, life-threatening, and fatal events in the Childhood Cancer Survivor Study. J Clin Oncol 32(12): 1218-1227, 2014.

Wasilewski-Masker K, Seidel KD, Leisenring W, Mertens AC, Shnorhavorian M, Ritenour CW, Stovall M, Green DM, Sklar CA, Armstrong GT, Robison LL, Meacham LR.  Male infertility in long-term survivors of pediatric cancer: A report from the Childhood Cancer Survivor Study. J Cancer Surviv 8(3): 437-447, 2014.

Cox CL, Nolan VG, Leisenring WM, Yasui Y, Ogg SW, Mertens AC, Neglia JP, Ness KK, Armstrong GT, Robison LL.  Noncancer- related mortality risks in adult survivors of pediatric malignancies: The Childhood Cancer Survivor Study. J Cancer Surviv 8(3): 460-471, 2014.

Qaddoumi I, Kocak M, Pai Panadiker AS, Armstrong GT, Wetmore C, Crawford J, Tong L, Boyett J, Kun LE, Boop FA, Merchant TE, Ellison DW, Gajjar A, Broniscer A.  Phase II Trial of Erlotinib during and after Radiotherapy in Children with Newly Diagnosed High-Grade Gliomas. Front Oncol 4:67, 2014.

Perkins JL, Chen Y, Harris A, Diller L, Stovall M, Armstrong GT, Yasui Y, Robison LL, , Sklar C.  Infections among long-term survivors of childhood and adolescent cancer:  A report from the Childhood Cancer Survivor Study. Cancer 120(16): 2514-2521, 2014.

Wong FL, Bhatia S, Landier W, Francisco L, Leisenring W, Hudson MM, Armstrong GT, Mertens A, Stovall M, Robison LL, Lyman GH, Lipshultz SE, Armenian SH.  Efficacy and cost-effectiveness of the Children’s Oncology Group long-term follow-up guidelines for early detection of treatment-related cardiac compromise in Childhood Cancer Survivors.  Ann Intern Med 160(10): 672-683. 2014.

Wilson CL, Stratton KL, Leisenring WL, Oeffinger KO, Nathan PC, Wasilewski-Masker K, Hudson MM, Castellino SM, Stovall M, Armstrong GT, Brinkman TM, Krull KR, Robison LL, Ness KK. Decline in physical activity level in the Childhood Cancer Survivor Study cohort. Cancer Epidemiol Biomarkers Prev 23(8): 1619-1627, 2014. 

Ewer M, Gianni L, Pane F, Sandri MT, Steiner RK, Wojnowski L, Yeh ET, Carver JR, Lipshultz SE, Minotti G, Armstrong GT, Cardinale D. Colan SD, Darby SC, Force TL, Kremer LC, Lenihan DJ, Sallan SE, Sawyer DB, Suter TM, Swain SM, van Leeuwen FE. Report on the international colloquium on cardio-oncology (Rome, 12-14 March 2014). Ecancermedicalscience 8:433, 2014.

Essig D, Li Q, Chen Y, Hitzler J, Leisenring W, Greenberg M, Sklar C, Hudson MM, Armstrong GT, Krull KR, Neglia JP, Oeffinger KC. Robison LL, Kuehni CE, Yasui Y, Nathan PC. Estimating the risk for late effects of therapy in children newly diagnosed with standard risk acute lymphoblastic leukemia using an historical cohort: A report from the Childhood Cancer Survivor Study. Lancet Oncol 15(8): 841-851, 2014.

Crom DB, Li Z, Brinkman TM, Hudson MM, Armstrong GT, Neglia J, Ness KK. Life satisfaction in adult survivors of childhood brain tumors. J Ped Oncol Nursing 31(6): 317-326, 2014.

Mulrooney DA, Nunnery S, Armstrong GT, Ness KK, Srivastava DK, Donovan D, Metzger ML, Krasin MJ, Joshi V, Durand JB, Robison LL, Hudson MM, Flamm SD.  Coronary Artery Disease Detected by Coronary Computed Tomographic Angiography (CCTA) in Adult Survivors of Childhood Hodgkin Lymphoma. Cancer 120(22): 3536-3544, 2014.

Gawade PL, Oeffinger KC, Sklar CA, Krull KR, Chemaitilly W, Stovall M, Leisenring W, Armstrong GT, Robison LL, Ness KK. Lifestyle, distress, and pregnancy outcomes in the Childhood Cancer Survivor Study cohort. Am J Obstet Gynecol 212(1):47.e1-47, 2015.

Smith WA, Li C, Nottage KA, Mulrooney DM, Armstrong GT, Lanctot JQ, Chemaitilly W, Laver J, Srivastava DK, Robison LL, Ness KK.  Lifestyle and metabolic syndrome in adult survivors of childhood cancer:  A report from the St. Jude Lifetime Cohort Study.  Cancer 120(17): 2742-2750, 2014. 

Chow EJ, Chen Y, Kremer LC, Breslow N, Hudson MM, Armstrong GT, Border WL, Feijen EAM, Green DM, Meacham LR, Meeske KA, Mulrooney DA, Ness KK, Oeffinger KC, Sklar CA, Stovall M, van der Pal HJ, Weather RE, Robison LL, Yasui Y.  Individual prediction of heart failure among childhood cancer survivors. J Clin Oncol 33(5): 394-402, 2015.

Jones LW, Liu Q, Armstrong GT, Ness KK, Yasui Y, Devine K, Tonorezos E, Soares-Miranda L, Sklar CA, Douglas PS, Robison LL, Oeffinger KC. Exercise and risk of major cardiovascular events in adult survivors of childhood Hodgkin lymphoma: A report from the Childhood Cancer Survivor Study. J Clin Oncol 32(32): 3643-3650, 2014.

Krull KR, Minoshima S, Edelmann M, Morris B, Sabin ND, Brinkman TM, Armstrong GT, Robison LL, Hudson MM, Shulkin B. Regional brain glucose metabolism and neurocognitive function in adult survivors of childhood cancer treated with cranial radiation. J Nucl Med 55(11): 1805-1810, 2014.

Tsui K, Gajjar A, Li C, Srivastava DK, Broniscer A, Wetmore C, Kun LE, Merchant TE, Ellison DW, Orr BA, Boop FA, Klimo P, Ross JD, Robison LL, Armstrong GT.  Subsequent Neoplasms in survivors of childhood central nervous system tumors: Risk after modern, multimodal therapy. Neuro-Oncology 17(3): 448-56, 2014.

Last update: June 2015