I-Chan Huang, PhD
I-Chan Huang, PhD

I-Chan Huang, PhD

Associate Member, St. Jude Faculty

Departments

Education

PhD – Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland
Postdoctoral Fellow – Center for Health Services and Outcomes Research, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland

Research Interests

  • Patient-reported outcomes in clinical application
  • Psychometric analysis
  • Quality of life and symptoms measurement in childhood cancers
  • Social network research in cancer survivors
  • Financial toxicity in childhood cancer

Current Research

  • NIH/NIAMS U01 Patient-Reported Outcomes Measurement Information System (PROMIS), Pediatric Asthma Study, Principal Investigator 
  • NIH/NCI R21 Symptom Progress and adverse health outcomes in adult childhood cancer survivors, Principal Investigator
  • NIH/NIAMS U19 The Child-Centered Outcomes in Practice and Research (COPR) Center of Excellence, Childhood Cancer Survivorship Study, Principal Investigator
  • NIH/NCI U01 Establishment of a Lifetime Cohort of Adults Surviving Childhood Cancer (SJLIFE), Co-Investigator

Selected Publications

Gandhi PK, Schwartz CE, Reeve BB, DeWalt DA, Gross HE, Huang IC.* An item-level response shift study on the change of health state with the rating of asthma-specific quality of life: a report from the PROMIS® Pediatric Asthma Study. Qual Life Res. 2016 Apr 9. PMID: 27061424. *Corresponding.

Li Z, Thompson LA, Gross HE, Shenkman EA, Reeve BB, DeWalt DA, Huang IC.* Longitudinal associations among asthma control, sleep problems, and health-related quality of life in children with asthma: a report from the PROMIS® Pediatric Asthma Study. Sleep Med. 20:41-50, 2016. *Corresponding

Wu AW, Wansom T, Huang IC, CoFrancesco J Jr, Conant MA, Sarwer DB. The Facial Appearance Inventory: Development and preliminary evidence for reliability and validity in people with HIV and lipoatrophy. Aesthet Surg J. 2016 Mar 1 (Epub). PMID: 26931304.

Howell CR, Thompson LA, Gross HE, Reeve BB, DeWalt DA, Huang IC.* Responsiveness to change in PROMIS® measures among children with asthma: A report from the PROMIS® Pediatric Asthma Study. Value Health. 19(2):192-201, 2016. PMCID: PMC4814775 *Corresponding.

Howell CR, Gross HE, Reeve BB, DeWalt DA, Huang IC.* Known-groups validity of the Patient-Reported Outcomes Measurement Information System (PROMIS) in adolescents and young adults with special healthcare needs. Qual Life Res. 2016 Feb 12 (Epub). PMID: 26872912 *Corresponding.

Thissen D, Liu Y, Magnus B, Quinn H, Gipson DS, Dampier C, Huang IC, Hinds PS, Selewski DT, Reeve BB, Gross HE, DeWalt DA. Estimating minimally important difference (MID) in PROMIS pediatric measures using the scale-judgment method. Qual Life Res. 25(1):13-23, 2016. PMCID: PMC4695321

Gandhi PK, Revicki DA, Huang IC.* Adolescent body weight and health-related quality of life rated by adolescents and parents: the issue of measurement bias. BMC Public Health. 15:1192, 2015. PMCID: PMC4663736. *Corresponding.

Reeve BB, Thissen D, DeWalt DA, Huang IC, Liu Y, Magnus B, Quinn H, Gross HE, Kisala PA, Ni P, Haley S, Mulcahey MJ, Charlifue S, A Hanks R, Slavin M, Jette A, Tulsky DS. Linkage between the PROMIS pediatric and adult emotional distress measures. Qual Life Res. 25(4):823-833, 2015. PMCID: PMC4814370

DeWalt DA, Gross HE, Gipson DS, Selewski DT, DeWitt EM, Dampier CD, Hinds PS, Huang IC, Thissen D, Varni JW. PROMIS® pediatric self-report scales distinguish subgroups of children within and across six common pediatric chronic health conditions. Qual Life Res. 24(9):2195-2208, 2015. PMCID: PMC4531096

Gandhi PK, Gentry WM, Kibert JL, Lee EY, Jordan W, Bottorff MB, Huang IC. The relationship between four health-related quality-of-life indicators and use of mammography and Pap test screening in US women. Qual Life Res. 24(9):2113-2128, 2015. PMCID: PMC4531104

Kenzik K, Huang IC, Rizzo JD, Shenkman E, Wingard J. Relationships among symptoms, psychosocial factors, and health-related quality of life in hematopoietic stem cell transplant survivors. Support Care Cancer. 23(3):797-807, 2015. PMCID: PMC4312505

Gandhi PK, Thompson LA, Tuli SY, Revicki DA, Shenkman E, Huang IC.* Developing item banks for measuring pediatric generic health-related quality of life: an application of the International Classification of Functioning, Disability and Health for Children and Youth and item response theory. PLoS One. 9(9):e107771, 2014. PMCID: PMC4182329. *Corresponding.

Kenzik KM, Huang I-C, Brinkman TM, Baughman B, Ness KK, Shenkman EA, Hudson MM, Robison LL, Krull KR. The Childhood Cancer Survivor Study-Neurocognitive Questionnaire (CCSS-NCQ) revised: item response analysis and concurrent validity. Neuropsychology 2014. Epub ahead of print. PMCID: PMC4268097.

Kenzik KM, Tuli S, Revicki D, Shenkman EA, Huang I-C*. Comparison of Four Pediatric Health-Related Quality-of-Life Instruments: A Study on a Medicaid Population. Med Decis Making. 34(5):590-602, 2014. PMCID: PMC4199940 *Corresponding.

Quinn GP, Murphy D, Fortier MA, Sehovic I, Eddleton KZ, Huang I-C. Quality of life tools and young adult survivors of pediatric cancer: A commentary on the need to examine perceptions of romantic relationships. J Adolesc Young Adult Oncol. 3(1):47-9, 2014. doi:10.1089/jayao.2013.0020.

Huang I-C. Measuring pediatric patient-reported outcomes: good progress but a long way to go. Qual Life Res. 23(3):747-750, 2014. PMCID: PMC4301734

Varni JW, Magnus B, Stucky BD, Liu Y, Quinn H, Thissen D, Gross HE, Huang I-C, DeWalt DA. Psychometric properties of the PROMIS® Pediatric Scales: Precision, stability, and comparison of different scoring and administration options. Qual Life Res. 23(4):1233-43, 2014. PMCID: PMC4312615

Gandhi PK, Ried LD, Kimberlin CL, Kauf TL, Huang I-C. Influence of explanatory and confounding variables on HRQoL – does measurement bias and/or response shift affect the results? Expert Rev Pharmacoecon Outcomes Res. 13(6):841-51, 2013. PMCID: PMC4308958

Huang I-C, Brinkman TM, Kenzik KM, Gurney JG, Ness KK, Lanctot J, Shenkman EA, Robison LL, Hudson MM, Krull KR. Association between the prevalence of symptoms and health-related quality of life in adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort study. J Clin Oncol. 31(33):4242-51, 2013. PMCID: PMC3821013

Huang I-C, Anderson M, Gandhi P, Tuli S, Krull K, Lai J-S, Nackashi J, Shenkman E. The relationships between fatigue, quality of life, and family impact among children with special health care needs. J Pediatr Psychol. 38(7):722-31, 2013. PMCID: PMC3721186

Li Z, Huang I-C*, Thompson LA, Tuli S, Huang S-W, DeWalt D, Revicki D, Shenkman E. The relationships between asthma control, daytime sleepiness, and quality of life among children with asthma: a path analysis. Sleep Med 14(7):641-7, 2013. PMCID: PMC3715592 *Corresponding.

Gandhi PK, Kenzik KM, Thompson LA, DeWalt DA, Revicki DA, Shenkman EA, Huang I-C.* Exploring factors influencing asthma control and asthma-specific health-related quality of life among children. Respir Res .14:26, 2013. PMCID: PMC3599064  Corresponding. Note, indicated by the publisher as a “highly access” article.

Gandhi P, Ried LD, Huang I-C, Kimberlin C, Kauf T. Assessment of response shift using two structural equation modeling techniques. Qual Life Res. 22(3):461-71, 2013. PMCID: PMC4295627

Quinn GP, Huang I-C, Murphy D, Zidonik-Eddelton K, Krull K. Missing content from health-related quality of life instruments: Interviews with young adult survivors of childhood cancer. Qual Life Res. 22(1):111-8, 2013. PMCID: PMC4291119

Show More

Huang I-C, Quinn QP, Krull KR, Eddleton KZ, Murphy DC, Shenkman EA, Shearer PD. Head-to-head comparisons of quality of life instruments for young adult survivors of childhood cancer. Support Care Cancer. 20(9):2061-71, 2012. PMCID: PMC3320678

Huang I-C, Quinn GP, Wen P-S, Shenkman EA, Revicki DA, Krull K, Li Z, Shearer PD. Using three legacy measures to develop a health-related quality of life tool for young adult survivors of childhood cancer. Qual Life Res. 21(8):1437-50, 2012. PMCID: PMC3328688

Pendley CL, Quinn GP, Shenkman EA, Curbow BA, Zebrack BJ, Huang I-C*. Quality of life of young adult survivors of childhood cancer: A review of qualitative studies. J Adolesc Young Adult Oncol. 1(3):124-32, 2011. PMCID: PMC3621306. Note, selected as a “feature article” for discussion in the 2013 Annual Conference of the Society for Adolescent and Young Adult Oncology (SAYAO). *Corresponding.

Huang I-C, Leite W, Shearer PD, Seid M, Revicki DA, Shenkman EA. Differential item functioning in pediatric quality of life measure between children with and without special health needs. Value Health. 14(6):872-83, 2011. PMCID: PMC3173710

Huang I-C, Wen P-S, Revicki DA, Shenkman EA. Quality of life measurement for children with life-threatening conditions: limitations and a new framework. Child Indic Res. 4(1):145-60, 2011. PMCID: PMC3133777

Werch CE, Bian H, Carlson J, Moore MJ, DiClemente CC, Huang I-C, Ames SC, Thombs D, Weiler RM, Pokorny SB. Brief integrative multiple behavior intervention effects and mediators for adolescents. J Behav Med. 34(1):3-12, 2011. PMID: PMC20661637

Huang I-C, Leite W, Shearer PD, Seid M, Revicki DA, Shenkman EA. Differential item functioning in pediatric quality of life measure between children with and without special health needs. Value Health. 14(6):872-83, 2011. PMCID: PMC3173710

Huang I-C, Wen P-S, Revicki DA, Shenkman EA. Quality of life measurement for children with life-threatening conditions: limitations and a new framework. Child Indic Res. 4(1):145-160, 2011. PMCID: PMC3133777

Huang I-C, Shenkman EA, Madden VL, Vadaparampiln S, Quinn G, Knapp CA. Measuring quality of life in pediatric palliative care: challenges and potential solutions. Palliat Med. 24(2):175-82, 2010. PMCID: PMC3810279

Huang I-C, Thompson LA, Chi Y-Y, Knapp CA, Revicki DA, Seid M, Shenkman EA. The linkage between pediatric quality of life and health conditions: establishing clinically meaningful cutoff scores for the PedsQL. Value Health. 12(5):773-81, 2009. PMCID: PMC4299816

Huang I-C, Shenkman EA, Leite W, Knapp CA, Thompson LA, Revicki DA. Agreement was not found in adolescents’ quality of life rated by parents and adolescents. J Clin Epidemiol. 62(3):337-46, 2009.  PMCID: PMC3812676

Huang I-C, Wu AW, Frangakis C. Do the SF-36 and WHOQOL-BREF measure the same constructs? Evidence from the Taiwan population. Qual Life Res. 15(1):15-24, 2006. PMID: 16411027

Last update: May 2016