Stan Pounds, PhD
Stan Pounds, PhD

Stan Pounds, PhD

Member, St. Jude Faculty

  • Director, Division of Biostatistics for Genomics and Neuroimaging

Departments

Education

BS – Harding University, Searcy, Arkansas (1997)
PhD – Texas A&M University, College Station, Texas (2002)

Research Interests

I develop statistical methods for various problems that arise in cancer genomics research.  Currently, my primary interests are in developing methods to integrate multiple pharmacologic and clinical endpoints with multiple forms of genomic data.  I am also interested in developing methods to identify genomic alterations that are biologically and clinically relevant.

Selected Publications

Ma X, Liu Y, Liu Y, Alexandrov LB, Edmonson MN, Gawad C, Zhou X, Li Y, Rusch MC, Easton J, Huether R, Gonzalez-Pena V, Wilkinson MR, Hermida LC, Davis S, Sioson E, Pounds S, Cao X, Ries RE, Wang Z, Chen X, Dong L, Diskin SJ, Smith MA, Auvil JMG, Meltzer PS, Lau CC, Perlman EJ, Maris JM, M S, Hunger SP, Gerhard DS, Zhang J. Pan-cancer genome and transcriptome analyses of 1,699 pediatric leukemias and solid tumors. Nature Published online Feb 28 2018.

Liu Y, Easton J, Shao Y, Maciaszek J, Wang Z, Wilkinson MR, Mccastlain K, Edmonson M, Pounds SB, Shi L, Zhou X, Ma Xi, Sioson E, Li Y, Rusch M, Gupta P, Pei D, Cheng C, Smith MA, Auvil JG, Gerhard DS, Relling MV, Winick NJ, Carroll AJ, Heerema NA, Raetz E, Devidas M, Wilman CL, Harvey RC, Carroll WL, Dunsmore KP, Winter SS, Wood BL, Sorrentino BP, Downing JR, Lo ML, Hunger SP, Zhang J, Mullighan CG. The Genomic Landscape of Pediatric and Young Adult T-Lineage Acute Lymphoblastic Leukemia. Nature Genetics 49:1211-1218, 2017.

Pinto EM, Rodriguez-Galindo C, Pounds S, Wang L, Clay MR, Neale G, Garfinkle EAR, Lam CG, Levy CF, Pappo AS, Zambetti GP, Ribeiro RC. Identification of Clinical and Biological Correlates Associated with Outcome in Children with Adrenocortical Tumors without Germline TP53 Mutations: A St. Jude Adrenocortical Tumor Registry and Children’s Oncology Group Study. Journal of Clinical Oncology 35:3956-3963, 2017.

Alexander TB, Wang L, Inaba H, Triplett BM, Pounds S, Riberio RC, Pui C-H, Rubnitz JE. Decreased relapsed rate and treatment related mortality contribute to improved outcomes for pediatric acute myeloid leukemia on successive clinical trials. Cancer 23:3791-3798, 2017.

Ramsey LB, Pounds S, Cheng C, Cao X, Yang W, Smith C, Karol SE, Liu C, Panetta JC, Inaba H, Rubnitz JE, Metzger ML, Ribeiro RC, Sandlund JT, Jeha S, Pui C-H, Evans WE, Relling MV. Genetics of Pleiotropic Effects of Dexamethasone. Pharmacogenetics and Genomics 27:294-302, 2017.

Zhu L, Poppleton H, Finkelstein D, Gao CL, Shi L, Wang Y-D, Terrada LT, Wang K, Utley S, Pounds S, Neale G, Ellison DW, Onar-Thomas A, Gilbertson RJ. Multi-organ mapping of cancer risk. Cancer Cell 166:1132-1146, 2016.  

Cao X, Crews KR, Downing J, Lamba J, Pounds SB. CC-PROMISE Effectively Integrates Two Forms of Molecular Data with Multiple Biologically Related Endpoints. BMC Bioinformatics 17:382, 2016.

Pawlikowska I, Wu G, Edmonson M, Liu Z, Gruber T, Zhang J, Pounds S. The Most Informative Spacing Test Effectively Discovers Biologically Relevant Outliers or Multiple Modes in Expression. Bioinformatics 30:1400-1408, 2014.

Pounds S, Cheng C, Li S, Liu Z, Zhang J, Mullighan C. A Genomic Random Interval Model for Statistical Analysis of Genomic Lesion Data. Bioinformatics 29:2088-95, 2013.

Last update: March 2018