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Matthew J. Ehrhardt, MD, MS
Matthew J. Ehrhardt, MD, MS

Matthew J. Ehrhardt, MD, MS

Associate Member, St. Jude Faculty




  • BS – University of Illinois, Urbana-Champaign
  • MD – University of Illinois College of Medicine at Peoria
  • MS – Medical College of Wisconsin, Milwaukee

Research Interests

  • Late effects of childhood cancer therapy
  • Hodgkin and non-Hodgkin lymphomas

Selected Publications

Ehrhardt MJ, Flerlage JE, Armenian SH, Castellino SM, Hodgson DC, Hudson MM. Integration of pediatric Hodgkin lymphoma treatment and late effects guidelines: seeing the forest beyond the trees. J Natl Compr Canc Netw 19(6):755-764, 2021. PubMed PMID: 34214967. DOI: 10.6004/jnccn.2021.7042. Role: First author

Metzger ML, Link MP, Billett AL, Flerlage J, Lucas JT Jr, Mandrell BN, Ehrhardt MJ, Bhakta N, Yock TI, Friedmann AM, de Alercon P, Luna-Fineman S, Larsen E, Kaste SC, Shulkin B, Lu Z, Li C, Hiniker SM, Donaldson SS, Hudson MM, Krasin MJ. Excellent outcome for pediatric patients with high-risk Hodgkin lymphoma treated with brentuximab vedotin and risk-adapted residual node radiation. J Clin Oncol 39(20):2276-2283, 2021. PubMed Central PMCID: PMC8260923. DOI: 10.1200/JCO.20.03286

van Dalen EC, Mulder RL, Suh E, Ehrhardt MJ, Aune GJ, Bardi E, Benson BJ, Bergler-Klein J, Chen MH, Frey E, Hennewig U, Lockwood L, Martinsson U, Muraca M, van der Pal H, Plummer C, Scheinemann K, Schindera C, Tonorezos ES, Wallace WH, Constine LS, Skinner R, Hudson MM, Kremer LCM, Levitt G, Mulrooney DA. Coronary artery disease surveillance among childhood, adolescent and young adult cancer survivors: A systematic review and recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group. Eur J Cancer Oct;156:127-137, 2021. PubMed PMID: 34450551. DOI: 10.1016/j.ejca.2021.06.021

Ehrhardt MJ, Williams AM, Liu Q, Scholle S, Bhakta N, Yasui Y, Robison LL, Hudson MM. Cumulative burden of chronic health conditions among adolescent and young adult survivors of childhood cancer: identification of vulnerable groups at key medical transitions. Pediatr Blood Cancer Jun;68(6):e29030, 2021. PubMed Central PMCID: PMC8068638. DOI: 10.1002/pbc.29030. Role: First author

Ehrhardt MJ, Ward ZJ, Liu Q, Chaudhry A, Nohria A, Border W, Fulbright JM, Mulrooney DA, Oeffinger KC, Nathan PC, Leisenring WM, Constine LS, Gibson TM, Chow EJ, Howell RM, Robison LL, Armstrong GT, Hudson MM, Diller L, Yasui Y, Armenian S, Yeh JM. Cost-effectiveness of the International Late Effects of Childhood Cancer Guideline Harmonization Group screening guidelines to prevent heart failure in childhood cancer survivors. J Clin Oncol 38(33):3851-3862, 2020. PubMed Central PMCID: PMC7676889. DOI: 10.1200/JCO.20.00418. Role: First author

Howell CR, Bjornard KL, Ness KK, Alberts N, Armstrong GT, Bhakta N, Brinkman T, Caron E, Chemaitilly W, Green DM, Folse T, Huang IC, Jefferies J, Kaste S, Krull K, Lanctot JQ, Mulrooney DA, Neale G, Nichols KE, Sabin ND, Shelton K, Srivastava DK, Wang Z, Wilson C, Yasui Y, Zaidi A, Zhang J, Robison LL, Hudson MM, Ehrhardt MJ. Cohort Profile: the St. Jude Lifetime Cohort Study (SJLIFE) for paediatric cancer survivors. Int J Epidemiol Mar 3;50(1):39-49, 2021. PubMed Central PMCID: PMC8453382. DOI: 10.1093/ije/dyaa203. Role: Senior author

Mulrooney DA, Ness KK, Hyun G, Ehrhardt MJ, Yasui Y, Duprez DA Shenoy C, Howell R, Leisenring WM, Constine LS, Oeffinger KC, Gibson TM, Tonorezos E, Robison LL, Hudson MM, Armstrong GT. Major cardiac events for adult survivors of childhood cancer diagnosed between 1970 and 1999: report from the Childhood Cancer Survivor Study cohort. BMJ 368(I6794), 2020. PubMed Central PMCID: PMC7190022. DOI: 10.1136/bmj.l6794

Ehrhardt MJ, Hochberg J, Bjornard KL, Brinkman TM. Long-term survivors of childhood, adolescent and young adult non-Hodgkin lymphoma. Br J Haematol 185(6):1099-110, 2019DOI: 10.1111/bjh.15775. Role: First author

Ehrhardt MJ, Skinner R, Castellino SM. Renal and hepatic health after childhood cancer. Clinics 67(6):1203-1217, 2020. DOI: 10.1016/j.pcl.2020.07.011. Role: First author

Armenian SH, Ehrhardt MJ. Optimizing cardiovascular care in children with acute myeloid leukemia to improve cancer-related outcomes. J Clin Oncol 37:1-6, 2019. PubMed PMID: 30422740. DOI: 10.1200/JCO.18.01421

Ehrhardt MJ, Chen Y, Sandlund JT, Bluhm EC, Hayashi RJ, Becktell K, Leisenring WM, Metzger ML, Ness KK, Krull KR, Oeffinger KC, Gibson TM, Cairo MS, Gross TG, Robison LL, Armstrong GT, Yasui Y, Hudson MM, Mulrooney DA. Late health outcomes after contemporary Lymphome Malin de Burkitt therapy for mature B-Cell Non-Hodgkin lymphoma: a Report From the Childhood Cancer Survivor Study. J Clin Oncol Jul 8:JCO1900525, 2019. PubMed Central PMCID: PMC7001792. DOI: 10.1200/JCO.19.00525. Role: First author

Ehrhardt MJ, Howell CR, Hale K, Baassiri MJ, Rodriguez C, Wilson CL, Joshi SS, Lemond TC, Shope S, Howell RM, Wang Z, Srivastava D, Mulrooney DA, Zhang J, Robison LL, Ness KK, Hudson MM. Subsequent breast cancer in female childhood cancer survivors in the St. Jude Lifetime Cohort Study (SJLIFE). J Clin Oncol Jul 1;37(19):1647-1656, 2019. PubMed Central PMCID: PMC6804891. DOI: 10.1200/JCO.18.01099. Role: First author

Ehrhardt MJ, Hochberg J, Bjornard KL, Brinkman TM. Long-term survivors of childhood, adolescent and young adult non-Hodgkin lymphoma. Br J Haematol Jun;185(6):1099-1110, 2019. PubMed PMID: 30714126. DOI: 10.1111/bjh.15775. Role: First author

Armenian SH, Armstrong GT, Aune G, Chow EJ, Ehrhardt MJ, Ky B, Moslehi J, Mulrooney DA, Nathan PC, Ryan TD, van der Pal HJ, van Dalen EC, Kremer LCM. Cardiovascular disease in survivors of childhood cancer: insights into epidemiology, pathophysiology, and prevention. J Clin Oncol Jul 20;36(21):2135-2144, 2018. PubMed Central PMCID: PMC6804893. DOI: 10.1200/JCO.2017.76.3920

Myers RM, Hill BT, Shaw BE, Kim S, Millard HR, Battiwalla M, Majhail NS, Buchbinder D, Lazarus HM, Savani BN, Flowers MED, D'Souza A, Ehrhardt MJ, Langston A, Yared JA, Hayashi RJ, Daly A, Olsson RF, Inamoto Y, Malone AK, DeFilipp Z, Margossian SP, Warwick AB, Jaglowski S, Beitinjaneh A, Fung H, Kasow KA, Marks DI, Reynolds J, Stockerl-Goldstein K, Wirk B, Wood WA, Hamadani M, Satwani P. Long-term outcomes among 2-year survivors of autologous hematopoietic cell transplantation for Hodgkin and diffuse large b-cell lymphoma. Cancer Feb 15;124(4):816-825, 2018. PubMed Central PMCID: PMC5871233. DOI: 10.1002/cncr.31114

Ehrhardt MJ, Mulrooney DA, Li C, Baassiri MJ, Bjornard K, Sandlund JT, Brinkman TM, Huang IC, Srivastava DK, Ness KK, Robison LL, Hudson MM, Krull KR. Neurocognitive, psychosocial, and quality-of-life outcomes in adult survivors of childhood non-Hodgkin lymphoma. Cancer Jan 15;124(2):417-425, 2018. PubMed Central PMCID: PMC5760296. PMCID: PMC5760296. DOI: 10.1002/cncr.31019. Role: First author

Bhakta N, Liu Q, Ness KK, Baassiri M, Eissa H, Yeo F, Chemaitilly W, Ehrhardt MJ, Bass J, Bishop MW, Shelton K, Lu L, Huang S, Li Z, Caron E, Lanctot J, Howell C, Folse T, Joshi V, Green DM, Mulrooney DA, Armstrong GT, Krull KR, Brinkman TM, Khan RB, Srivastava DK, Hudson MM, Yasui Y, Robison LL. The cumulative burden of surviving childhood cancer: an initial report from the St. Jude Lifetime Cohort Study (SJLIFE). Lancet Dec 9;390(10112):2569-2582, 2017. PubMed Central PMCID: PMC5798235. DOI: 10.1016/S0140-6736(17)31610-0

Bjornard KL, Leventaki V, Nichols KE, Sandlund JT, Prockop S, Ehrhardt MJ. Two-year-old female with EBV-positive diffuse large B-cell lymphoma and subsequent CNS involvement with neurolymphomatosis. Pediatr Blood Cancer Dec;65(12):e27415, 2018. PubMed Central PMCID: PMC8244825. DOI: 10.1002/pbc.27415. Role: Senior author

Hudson MM, Ehrhardt MJ, Bhakta N, Baassiri M, Eissa H, Chemaitilly W, Green DM, Mulrooney DA, Armstrong GT, Brinkman TM, Klosky JL, Krull KR, Sabin ND, Wilson CL, Huang IC, Bass JK, Hale K, Kaste S, Khan RB, Srivastava DK, Yasui Y, Joshi VM, Srinivasan S, Stokes D, Hoehn ME, Wilson M, Ness KK, Robison LL. Approach for classification and severity grading of long-term and late-onset health events among childhood cancer survivors in the St. Jude Lifetime Cohort. Cancer Epidemiol Biomarkers Prev May;26(5):666-674, 2017. PubMed Central PMCID: PMC5413397. DOI: 10.1158/1055-9965.EPI-16-0812

Ehrhardt MJ, Sandlund JT, Zhang N, Liu W, Ness KK, Bhakta N, Chemaitilly W, Krull KR, Brinkman TM, Crom DB, Kun L, Kaste SC, Armstrong GT, Green DM, Srivastava K, Robison LL, Hudson MM, Mulrooney DA. Late outcomes of adult survivors of childhood non-Hodgkin lymphoma: a report from the St. Jude Lifetime Cohort Study. Pediatr Blood Cancer Jun;64(6), 2017. PubMed Central PMCID: PMC5403569. DOI: 10.1002/pbc.26338. Role: First author

Bhakta N, Liu Q, Yeo F, Baassiri M, Ehrhardt MJ, Srivastava DK, Metzger ML, Krasin MJ, Ness KK, Hudson MM, Yasui Y, Robison LL. Cumulative burden of cardiovascular morbidity in paediatric, adolescent, and young adult survivors of Hodgkin's lymphoma: an analysis from the St. Jude Lifetime Cohort Study. Lancet Oncol Sep;17(9):1325-1334, 2016. PubMed Central PMCID: PMC5029267. DOI: 10.1016/S1470-2045(16)30215-7

Ehrhardt MJ, Bhakta N, Liu Q, Yasui Y, Krasin MJ, Mulrooney DA, Hudson MM, Robison LL. Absence of Basal cell carcinoma in irradiated childhood cancer survivors of black race: a report from the St. Jude Lifetime Cohort Study. Cancer Epidemiol Biomarkers Prev Sep;25(9):1356-1360, 2016. PubMed Central PMCID: PMC5010444. DOI: 10.1158/1055-9965.EPI-16-0280. Role: First author

Mulrooney DA, Armstrong GT, Huang S, Ness KK, Ehrhardt MJ, Joshi VM, Plana JC, Soliman EZ, Green DM, Srivastava D, Santucci A, Krasin MJ, Robison LL, Hudson MM. Cardiac outcomes in adult survivors of childhood cancer exposed to cardiotoxic therapy: a cross-sectional study. Ann Intern Med Jan 19;164(2):93-101, 2016. PubMed Central PMCID: PMC4809016. DOI: 10.7326/M15-0424

Ehrhardt MJ, Brazauskas R, He W, Rizzo JD, Shaw BE. Survival of patients who develop solid tumors following hematopoietic stem cell transplantation. Bone Marrow Transplant Jan;51(1):83-88, 2016. PubMed Central PMCID: PMC4570237. DOI: 10.1038/bmt.2015.203

Last update: February 2022