Diego R. Hijano, MD, MSc
Diego R. Hijano, MD, MSc

Diego R. Hijano, MD, MSc

Assistant Member, St. Jude Faculty

Departments

Education

MD - National University of La Plata, Argentina
MSc - University of Buenos Aires, Argentina

Research Interests

  • Host-pathogen interactions of respiratory virus
  • Systemic viral infections in immunocompromised host
  • Infections in bone marrow transplant recipients

Selected Publications

Hijano DR; Brazelton de Cardenas J; Maron G; Garner CD; Ferrolino JA; Dallas RH ; Gu Z;  Hayden RT. Clinical Correlation of Influenza and Respiratory Syncytial Virus Load Measured by Digital PCR. PLoS ONE 14(9), 2019. e0220908.

Hijano DR, Vu LD, Kauvar LM, Tripp RA, Polack FP, Cormier SA. Role of Type I Interferon (IFN) in the Respiratory Syncytial Virus (RSV) Immune Response and Disease Severity. Front Immunol. 10:566, 2019. doi: 10.3389/fimmu.2019.00566. eCollection 2019. Review. PMID: 30972063

Hijano DR, Otterson D, Homsi MR, Su Y, Tang L, Kirby J, Caniza MA. Brown Recluse Spider Bites in Patients With Neutropenia: A Single-institution Experience. J Pediatr Hematol Oncol. 41(1):28-33, 2019. doi: 10.1097/MPH.0000000000001253. PMID: 30028826

Hijano DR, Maron G, Hayden RT. Respiratory Viral Infections in Patients With Cancer or Undergoing Hematopoietic Cell Transplant.  Front Microbiol. 9:3097, 2018. doi: 10.3389/fmicb.2018.03097. eCollection 2018. Review. PMID: 30619176

Hijano DR, Siefker DT, Shrestha B, Jaligama S, Vu LD, Tillman H, Finkelstein D, Saravia J, You D, Cormier SA. Type I Interferon Potentiates IgA Immunity to Respiratory Syncytial Virus Infection During Infancy. Sci Rep. 8(1):11034, 2018. doi: 10.1038/s41598-018-29456-w. PMID: 3003829

Caballero MT, Hijano DR*, Acosta PL, Mateu CG, Marcone DN, Linder JE, Talarico LB, Elder JM, Echavarria M, Miller EK, Polack FP; INFANT Respiratory Network. Interleukin-13 associates with life-threatening rhinovirus infections in infants and young children. Pediatr Pulmonol. 53(6):787-795, 2018. doi: 10.1002/ppul.23998. Epub 2018 Apr 17. PMID: 29665312

Jiang C, Whitmore-Sisco L, Gaur AH, Adderson EE; Tdap Working Group. A quality improvement initiative to increase Tdap (tetanus, diphtheria, acellular pertussis) vaccination coverage among direct health care providers at a children's hospital. Vaccine. 36(2):214-219, 2018. doi: 10.1016/j.vaccine.2017.11.071. Epub 2017 Dec 6. PMID: 29217370

Talarico LB, Batalle JP, Byrne AB, Brahamian JM, Ferretti A, García AG, Mauri A, Simonetto C, Hijano DR, Lawrence A, Acosta PL, Caballero MT, Rojas YP, Ibañez LI, Melendi GA, Rey FA, Damonte EB, Harris E, Polack FP. The role of heterotypic DENV-specific CD8+T lymphocytes in an immunocompetent mouse model of secondary dengue virus infection. EbioMedicine June;20:202-216, 2017. DOI: http://dx.doi.org/10.1016/j.ebiom.2017.04.033

Hijano DR, Siefker D, You D, Cormier SA. Understanding the Importance of Mucosal Immunity in Mediating Protection against RSV Infection: A Role for Age and IgA Production. JSM Allergy Asthma 2(1):1006, 2017.

Libster R*, Ferolla FM*, Hijano DR*, Acosta PL, Erviti A, Polack FP, for the INFANT Respiratory Network†. Alcohol during pregnancy worsens acute respiratory infections in children. Foundation Acta Pædiatr 104:e494–e499, 2015. PMID: 26249835

Caballero MT, Serra ME, Acosta PL, Marzec J, Gibbons L, Salim M, Rodriguez A, Reynaldi A, Garcia A, Bado D, Buchholz UJ, Hijano DR, Coviello S, Newcomb D, Bellabarba M, Ferolla FM, Libster R, Berenstein A, Siniawaski S, Blumetti V, Echavarria M, Pinto L, Lawrence A, Ossorio MF, Grosman A, Mateu CG, Bayle C, Dericco A, Pellegrini M, Igarza I, Repetto HA, Grimaldi LA, Gudapati P, Polack NR, Althabe F, Shi M, Ferrero F, Bergel E, Stein RT, Peebles RS, Boothby M, Kleeberger SR, Polack FP. TLR4 genotype and environmental LPS mediate RSV bronchiolitis through Th2 polarization. J Clin Invest 125(2):571–582, 2015. PMCID: PMC4319428

Ferolla FM*, Hijano DR*, Acosta PL*, Rodríguez A, Dueñas K, Sancilio A, Barboza E, Caría A, Gago GF, Almeida RE, Castro L, Pozzolo C, Martínez MV, Grimaldi LA, Rebec B, Calvo M, Henrichsen J, Nocito C, González M, Barbero G, Losada JV, Caballero MT, Zurankovas V, Raggio M, Schavlovsky G, Kobylarz A, Wimmenauer V, Bugna J, Williams JV, Sastre G, Flamenco E, Pérez AR, Ferrero F, Libster R, Grijalva CG, Polack FP. Macronutrients during pregnancy and life-threatening respiratory syncytial virus infections in children. Am J Respir Crit Care Med 187(9):983-990, 2013. PMID: 23449690

Talarico LB, Bugna J, Wimmenauer V, Espinoza MA, Quipildor MO, Hijano DR, Beccaria M, Wurster V, Cavagnaro LE, Martinez D, Fattore G, Batalle JP, Acosta PL, Reynoso N, Melendi GA, Rey FA, Libster R, Polack FP. T helper type 2 bias and type 17 suppression in primary dengue virus infection in infants and young children. Trans R Soc Trop Med Hyg 107(7):411-419, 2013. PMID: 23764739

Bonet F, Allegri R, Bernet J, Bossio P, Clacheo R, Hijano D, Jensen O, Pedetta G, Pérez L, Salinas D, Sottile S, del Barco VP. Situational diagnosis of the health research at the National and 10 Provincial Ministries of Health in Argentina. Revista Argentina de Salud Pública 3(10):1852-8724, 2012.

Miller KE, Bugna J, Libster R, Shepherd BE, Scalzo MP, Acosta PA, Hijano DR, et al. Human rhinoviruses in severe respiratory disease in very low birth weight infants. Pediatrics 29(1):e60-e67, 2012. PMCID: PMC3255465

Miller EK, Hernandez JZ, Wimmenauer V, Shepherd BE, Hijano D, Libster R, Serra ME, Bhat N, Batalle JP, Mohamed Y, Reynaldi A, Rodriguez A, Otello M, Pisapia N, Bugna J, Bellabarba M, Kraft D, Coviello S, Ferolla FM, Chen A, London SJ, Siberry GK, Williams JV, Polack FP. A mechanistic role for type III interferon-λ1 in asthma exacerbations mediated by human rhinoviruses. Am J Respir Crit Care Med 185(5):508-5161, 2012. PMCID: PMC3361761

Libster R, Bugna J, Coviello S, Hijano DR, Dunaiewsky M, Reynoso N, Cavalieri ML, Guglielmo MC, Areso MS, Gilligan T, Santucho F, Cabral G, Gregorio GL, Moreno R, Lutz MI, Panigasi AL, Saligari L, Caballero MT, Egües Almeida RM, Gutierrez Meyer ME, Neder MD, Davenport MC, Del Valle MP, Santidrian VS, Mosca G, Garcia Dominguez M, Alvarez L, Landa P, Pota A, Bolonati N, Dalamon R, Sanchez Mercol VI, Espinoza M, Peuchot JC, Karolinski A, Bruno M, Borsa A, Ferrero F, Bonina A, Ramonet M, Albano LC, Luedicke N, Alterman E, Savy V, Baumeister E, Chappell JD, Edwards KM, Melendi GA, Polack FP.  Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina. N Engl J Med 362:45-55, 2010. PMID: 20032320

Last update: December 2019

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