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Anand Patel, MD, PhD
Anand Patel, MD, PhD

Anand Patel, MD, PhD

Assistant Member, St. Jude Faculty

Departments

Divisions

Education

  • BSE – Pratt School of Engineering, Duke University, Durham, North Carolina
  • MD – Mayo Medical School, Rochester, Minnesota
  • PhD – Mayo Graduate School, Rochester, Minnesota
  • Internship and Residency (General Pediatrics) - St. Louis Children's Hospital/Washington University in St. Louis, St. Louis, Missouri
  • Clinical Fellowship (Pediatric Hematology/Oncology) - St. Jude Children's Research Hospital, Memphis, Tennessee  

Honors & Awards

  • 2020-2024 - Damon Runyon-Sohn Pediatric Cancer Research Fellowship
  • 2022 - Alex’s Lemonade Stand Resource Sharing Award 
  • 2022 - Damon Runyon-Jake Wetchler Award for Pediatric Innovation
  • 2022 - AACR NextGen Star
  • 2019 - Hyundai Hope on Wheels Young Investigator Award
  • 2019 - Alex's Lemonade Stand Young Investigator Award
  • 2016 - Alpha Omega Alpha Medical Honor Society
  • 2014 - James P. Keating Outstanding Resident Award
  • 2004 - Phi Beta Kappa Humanities Honor Society
  • 2004 - Tau Beta Pi Engineering Honor Society
  • 2003-2004 - Pratt Engineering Undergraduate Fellowship

Research Interests

  • Intratumoral heterogeneity of pediatric solid tumors
  • Mechanism of treatment resistance and persistence
  • Spatial organization of the tumor microenvironment

Selected Publications

Sengupta S, Das S, Crespo AC, Cornel AM, Patel AG, Mahadevan NR, Campisi M, Ali AK, Sharma B, Rowe JH, Huang H, Debruyne DN, Cerda ED, Krajewska M, Dries R, Chen M, Zhang S, Soriano L, Cohen MA, Versteeg R, Jaenisch R, Spranger S, Romee R, Miller BC, Barbie DA, Nierkens S, Dyer MA, Lieberman J, George RE. Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes. Nat Cancer 3(10):1228-1246, 2022.

Zeineldin M, Patel AG, Dyer MA. Neuroblastoma: When Differentiation Goes Awry. Neuron 110(18):2916-2928, 2022.

Patel AG*, Chen X*, Huang X*, Clay MR, Komarova N, Krasin MJ, Pappo A, Tillman H, Orr BA, McEvoy J, Gordon B, Blankenship K, Reilly C, Zhou X, Norrie J, Karlstrom A, Yu J, Wodarz D, Stewart E, Dyer MA. The Myogenesis Program Drives Clonal Selection and Drug Resistance in Rhabdomyosarcoma. Dev Cell 27(10):1226-1240, 2022. *co-first authors

Honnell V, Norrie JL, Patel AG, Ramirez C, Zhang J, Lai Y-H, Wan S, Dyer MA. Identification of a modular super-enhancer in retinal development. Nat Commun 13:253, 2022.

Clay M*, Patel A*, Tran Q, Hedges DJ, Cheng T, Stewart E, Charville G, Cline C, Dyer MA, Orr BA*. Methylation profiling reveals novel molecular classes of rhabdomyosarcoma. Sci Rep 11:22213, 2021. *co-first authors

Durbin AD, Wang T, Wimalasena VK, Zimmerman MW, Li D, Dharia NV, Mariani L, Shendy NAM, Nance S, Patel AG, Shao Y, Mundada M, Maxham L, Park PMC, Sigua LH, Morita K, Conway AS, Robichaud AL, Perez-Atayde AR, Bikowitz MJ, Quinn TR, Wienst OG, Easton J, Schönbrunn E, Bulyk M, Abraham BJ, Stegmaier K, Look AT, Qi J. EP300 selectively controls the enhancer landscape of MYCN- amplified neuroblastoma. Cancer Discov 12(3):730-751, 2021.

Nguyen R*, Patel AG*, Griffiths LM, Dapper J, Stewart EA, Houston J, Johnson M, Akers WJ, Furman, WL, Dyer MA. Next generation humanized patient-derived xenograft mouse model for preclinical antibody studies in neuroblastoma. Cancer Immunol Immunother 70(3):721-732, 2021. *co-first authors

Slyper M, Porter CBM, Ashenberg O, Waldman J, Drokhlyansky E, Wakiro I, Smillie C, Smith-Rosario G, Wu J, Dionne D, Vigneau S, Jané-Valbuena J, Tickle TL, Napolitano S, Su M, Patel AG, Karlstrom A, Gritsch S, Nomura M, Waghray A, Gohil SH, Tsankov AM, Jerby-Arnon L, Cohen O, Klughammer J, Rosen Y, Gould J, Nguyen L, Hofree M, Tramontozzi PJ, Li B, Wu CJ, Izar B, Haq R, Hodi FS, Yoon CH, Hata AN, Baker SJ, Suvà ML, Bueno R, Stover EH, Clay MR, Dyer MA, Collins NB, Matulonis UA, Wagle N, Johnson BE, Rotem A, Rozenblatt-Rosen O, Regev A. A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors. Nat Med 26(5):792-802, 2020.

Last update: September 2023

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