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Giedre Krenciute, PhD

Associate Member, St. Jude Faculty

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Contact Information

Giedre Krenciute, PhD

Bone Marrow Transplantation & Cellular Therapy

MS 310, Room I4104

St. Jude Children's Research Hospital

262 Danny Thomas Place

MemphisTN 38105-3678

Education

BS - Vilnius University, Vilnius, Lithuania

PhD - Baylor College of Medicine, Houston, TX

Research Interests

  • Generating and optimizing novel and safe CAR T cell-based therapies to target pediatric brain tumors
  • Enhancing CAR T persistence and efficacy using different genetic manipulations
  • Understanding tumor escape mechanism post CAR T-cell treatment
  • Understanding CAR T-cell functional memory programs that control their long-term effector function
  • Defining CAR T-cell and brain tumor immune microenvironment (TIME) interactions using immune competent brain tumor models