Patricia J. Dubin, MD

Patricia J. Dubin, MD

  • Consulting Physician, Pulmonology
  • Chief, Division of Pediatric Pulmonology, Allergy, Immunology and Sleep Medicine, University of Tennessee Health Science Center

Departments

Education

MD – University of Rochester School of Medicine and Dentistry
Internship – Yale-New Haven Children’s Hospital
Residency – Yale-New Haven Children’s Hospital
Postgraduate Training – Children’s Hospital of Pittsburgh

Clinical Interests

  • Pediatric Pulmonology

Selected Publications

Lee B, Robinson K, McHugh K, Scheller E, Mandalapu S, Chen C, Di Y, Clay M, Enelow R, Dubin P, Alcorn J. Influenza-induced Type I Interferon Enhances Susceptibility to Gram-negative and Gram-positive Bacterial Pneumonia in Mice. Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15;309(2): L158-67. doi: 10.1152/ajplung.00338.2014. Epub 2015 May 22.

Dubin PJ, Martz A, Eisenstatt JR, Fox MD, Logar A, Kolls JK. Interleukin-23-Mediated Inflammation in Pseudomonas aeruginosa Pulmonary Infection. Infection and Immunity, 2012 Jan; 80(1): 398-409.

Kudva A, Scheller EV, Robinson KM, Crowe CR, Slight SR, Khader SA, Dubin PJ, Enelow RI, Kolls JK and Alcorn JFA.  Influenza A Inhibits TH17 Mediated Host Defense against Bacterial Pneumonia in Mice. J Immunol, 2011 Feb 1; 186(3):1666-74

Losee JE, Natali M, Grunwaldt L, Chao-Mills M, Dubin PJ, McIntire S, Jiang S, Vecchione L, Kane T, Schneck F, Cladis F. Induced restrictive lung disease and secondary to tissue expansion in ischiopagus conjoined twins. Plast Reconstr Surg. 2009 Apr; 123(4):1378-83.

Aujla SJ, Chan YR, Fei M, Askew DJ, Pociask DA, Reinhart TA, McAllister F, Edeal J, Gaus K, Husain S, Kreindler J, Dubin PJ, Zheng M, PIlewski JP, Myerburg MM, Mason CA, Iwakura Y and Kolls JK. IL-22 mediates mucosal host defense against gram negative bacterial pneumonia. Nat Med. 2008 March 01; 14, 275 – 281.

Dubin PJ, Kolls J.  IL-23 mediates inflammatory responses to mucoid Pseudomonas aeruginosa lung infection in mice. Am J Physiol Lung Cell Mol Physiol. 2007 Feb; 292(2):L519-28.

Happel KH#, Dubin PJ#, Zheng MQ#, Quinton LJ, Odden A, Shellito JE, Bagby GJ, Nelson SJ, Kolls JK. Divergent Roles of IL-12 and IL-23 in host defense against Klebsiella pneumoniae. J Exp Med. 2005 Sep 19; 202(6):761-9. Epub 2005 Sep 12 # designates equal contribution.

Hashimoto K, Durbin J, Zhou W, Collins RD, Ho SB, Kolls JK, Dubin PJ, Sheller JR, Goleniewska K, O’Neal JF, Olson SJ, Mitchell D, Graham BS Peebles RS. Respiratory syncytial virus infection in the absence of STAT1 results in airway dysfunction, induction of airway mucus, and augmented IL-17 production. J Allergy and Clin Immunol. 2005 Sep; 116(3):550-7.

McAllister F, Henry A, Kreindler JL, Dubin PJ, Steele C, Finder JD, Pilewski JM, Carreno BM, Goldman  SJ, Pirhonen J, Kolls JK.  Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. J Immunol. 2005 Jul 1;175(1):404-12.

Last update: March 2018