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Updates on gene therapy for ‘bubble boy’ disease and cellular immunotherapy at ASGCT
05/12/2022
St. Jude scientists will discuss research on cellular therapies for pediatric cancer and more at the annual meeting.
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A tool to unlock the ‘numbers game’ of big data in rare disease research
05/11/2022
Big data can cause big problems in rare disease genetics research. Scientists at St. Jude created a systematic solution to find the inherited genes contributing to rare disease.
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Strategy overcomes EZH2 inhibitor resistance in SMARCB1 mutated cancer
05/09/2022
Findings from St. Jude demonstrate the role of chromatin regulation in cancer’s resistance to EZH2 inhibitors and offer a way to make treatment more effective.
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Lab findings suggest EGFR inhibitors may prevent rhabdomyosarcoma recurrence
04/27/2022
RMS is the most common soft tissue sarcoma in children. When it recurs after therapy, the survival rate is only 30%.
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Single-molecule techniques illuminate mechanisms of GPCR activation
04/27/2022
St. Jude scientists and their Columbia University collaborators reveal how GPCR signaling is regulated with implications for drug development.
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Study finds jumping “junk” DNA is a novel cause of childhood brain cancer
04/22/2022
St. Jude scientists have found the first known example of a promoter ‘donation’ event from a retrotransposon causing a highly malignant childhood brain cancer.
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J. Paul Taylor, M.D., Ph.D., named scientific director and executive vice president of St. Jude
04/18/2022
Dr. Taylor steps into the role during a pivotal time of growth for St. Jude, as its scientific enterprise will significantly expand.
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American Society of Clinical Oncology honors St. Jude clinical brain tumor researcher
04/12/2022
Dr. Amar Gajjar becomes the seventh St. Jude Children’s Research Hospital investigator to receive the Pediatric Oncology Award
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Dr. Martine Roussel recognized for groundbreaking work
04/10/2022
The AACR also honored the St. Jude scientist for her contributions to advancing women in science.
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St. Jude researchers honored for contributions to treatment of pediatric blood disorders
04/06/2022
St. Jude researchers are recognized by the American Society of Pediatric Hematology/Oncology for their expertise and career achievements
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Immune responses support COVID-19 vaccination regardless of when people were infected
04/05/2022
St. Jude scientists have studied how vaccination before and after primary infections affect the immune response.
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St. Jude at the American Association for Cancer Research Annual Meeting
03/30/2022
Scientists from St. Jude Children’s Research Hospital will participate in the annual gathering of a premier professional society for the cancer research community.
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St. Jude Children’s Research Hospital evacuates second group of patients from Ukraine safely to United States
03/29/2022
Four more Ukrainian children with cancer and their 11 family members arrived at St. Jude Children’s Research Hospital in Memphis, Tennessee.
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First Ukrainian pediatric cancer patients evacuated to U.S. arrive safely at St. Jude Children’s Research Hospital
03/22/2022
St. Jude continues to help move hundreds of Ukrainian children with cancer to safety so they can continue treatment.
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James R. Downing, M.D., elected to Fellows of AACR Academy Class of 2022
03/22/2022
Dr. Downing is honored for his outstanding contributions and innovations in cancer research.
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Chronologically young, biologically old – DNA linked to cancer survivors’ premature aging
03/22/2022
St. Jude Children’s Research Hospital findings lay the groundwork for identifying pediatric cancer survivors at higher risk of accelerated aging and chronic diseases.
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Memphis Airport to open unique lounge for St. Jude Children’s Research Hospital
03/07/2022
Private, comfortable space in newly designed airport concourse will be staffed by St. Jude employees.
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With Fundacja Herosi, St. Jude aids Ukrainian children with cancer and blood disorders at Unicorn Marian Wilemski Clinic
03/06/2022
On Saturday, the Foundation’s building in Bocheniec, now officially named the Unicorn Marian Wilemski Clinic, welcomed the first group of Ukrainian children and their families. Read more about this ongoing effort.
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St. Jude creates HPV cancer prevention awareness campaign to emphasize the need for HPV vaccination
03/04/2022
Emphasizing the need for HPV vaccination, the campaign launches March 4, 2022, International HPV Awareness Day.
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Research reveals high-risk subtype of relapsed pediatric AML
02/17/2022
St. Jude scientists have found a previously overlooked mutation in a subtype of pediatric leukemia that has implications for identifying high-risk patients.
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St. Jude leases interim office space in Peabody Place as campus grows
02/16/2022
The hospital relocates 500 administrative employees to the temporary workspace during the construction phase of its six-year strategic plan.
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Research lays a foundation for prevention of the most common childhood cancer
02/07/2022
St. Jude scientists blocked development of acute lymphoblastic leukemia in mice with a genetic mutation that increases the risk of childhood cancer.
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St. Jude Children’s Research Hospital celebrates 60 years of saving children’s lives
02/04/2022
Diamond jubilee events are planned nationwide for supporters to honor St. Jude visionaries, recognize expanding global impact of scientific, medical achievements
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Young vs. old: How host environment affects immune response
02/04/2022
St. Jude scientists have shown that the active immune system in young hosts may actually work against cancer immunotherapies by exhausting T cells.
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Inherited gene variant powers up an oncogene to drive a high-risk leukemia
02/03/2022
Scientists at St. Jude have revealed how an inherited genetic variant turns on an oncogene, increasing the risk of developing childhood leukemia. Published in Nature Genetics.
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CAR T cells target AML, spare bone marrow
01/31/2022
St. Jude scientists created an immunotherapeutic strategy for a type of pediatric leukemia using CAR T cells that target a tumor-specific antigen.
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Genetic ancestry provides important context for understanding global diversity in childhood leukemia
01/27/2022
St. Jude scientists show that addressing racial disparities in acute lymphoblastic leukemia should include considering how genetic ancestry affects biology and prognosis.
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Common cold coronaviruses hinder antibody immune response to SARS-CoV-2 infection
01/12/2022
St. Jude study also suggests that prior immunity to common cold coronaviruses does not protect against SARS-CoV-2 infection.
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Modular super-enhancer controls retinal development
01/11/2022
Scientists at St. Jude identified distinct functions for regions of a super-enhancer that controls gene expression during retina formation, calling it a ‘modular’ super-enhancer.
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Understanding how autoactivation triggers cell death
01/11/2022
Scientists from St. Jude have captured the structure of autoactivated BAK, a key protein for triggering apoptosis in cancer cells.
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St. Jude Mom Boss Summit celebrates strength and community amid challenges of motherhood, work, wellness
05/12/2022
Hundreds of influencers, business leaders, entrepreneurs and supporters of St. Jude convened in a virtual gathering on Thursday, May 5, for the annual St. Jude Mom Boss Summit.
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Run Rich Run kicks off 60 Days for St. Jude during 60th anniversary of St. Jude Children’s Research Hospital
05/03/2022
In its 18th year, Emmy-nominated NFL Network host Rich Eisen kicked off his annual event at the Rose Bowl, in Pasadena, California.
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Tri Delta beats the clock to raise $60 million for St. Jude Children’s Research Hospital
04/14/2022
International women’s organization and longtime partner Tri Delta completed its 10-year, $60 million fundraising commitment two years ahead of schedule.
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Holi celebrations make a splash at St. Jude Children’s Research Hospital
03/24/2022
Through March 31, St. Jude supporters can tap into their creativity and embrace their inner artist through a campaign called “Spring Into Holi, Splash Into Color.”
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