Yongqiang Feng, PhD
Yongqiang Feng, PhD

Yongqiang Feng, PhD

Assistant Member, St. Jude Faculty



PhD - Rutgers, the State University of New Jersey
Postdoctoral Fellow - Memorial Sloan Kettering Cancer Center

Honors & Awards

  • 2016  MSK Postdoctoral Researcher Award
  • 2011-2013  Bristol-Myers Squibb/Irvington Institute Fellowship

Research Interests

  • Epigenetic regulation of T cell lineage specification and function
  • Molecular basis of T cell stability and plasticity 
  • Development of new tools to study T cell biology

Selected Publications

Chinen T, Kannan AK, Levine AG, Fan X, Klein U, Zheng Y, Gasteiger G, Feng Y, Fontenot JD, Rudensky AY. An essential role for the IL-2 receptor in Treg cell function. Nat Immunol 17:1322-1333. 2016.

Feng Y, van der Veeken J, Osmanbeyoglu HU, Dikiy S, Hoyos BE, Treuting P, Leslie CS, Rudensky AY. A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance. Nature 528:132-136, 2015.

Feng Y, Rudensky AY. DNA methylation secures CD4+ and CD8+ T cell lineage borders. Nat Immunol 16:681-683, 2015.

Feng Y, Arvey A, Chinen T, van der Veeken J, Gasteiger G, Rudensky AY. Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus. Cell 158:749-763, 2014.

Arvey A, van der Veeken J, Samstein RM, Feng Y. Stamatoyannopoulos, J.A., and Rudensky, A.Y. Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells. Nat Immunol 15:580-587, 2014.

Pan G, Feng Y, Ambegaonkar AA, Sun G, Huff M, Rauskolb C, Irvine KD. Signal transduction by the Fat cytoplasmic domain. Development 140:831-842, 2013.

Ambegaonkar AA, Pan G, Mani M, Feng Y, Irvine KD. Propagation of dachsous-fat planar cell polarity. Curr Biol 22:1302-8, 2012.

Feng Y, Irvine KD. Processing and phosphorylation of the Fat receptor. Proc Natl Acad Sci U S A 106:11989-11994, 2009.

Feng Y, Irvine KD. Fat and expanded act in parallel to regulate growth through warts. Proc Natl Acad Sci U S A 104:20362-20367, 2007.

Cho E*, Feng Y*, Rauskolb C, Maitra S, Fehon R, Irvine KD. Delineation of a Fat tumor suppressor pathway. Nat Genet 38:1142-1150, 2006. (*Contributed equally).

Last update: October 2016