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Qian Li, PhD
Qian Li, PhD

Qian Li, PhD

Assistant Member, St. Jude Faculty

Departments

Education

Postdoctoral Fellowship - Moffitt Cancer Center, Tampa, FL
Postdoctoral Fellowship - University of Kansas Medical Center, Kansas City, KS
PhD (Statistics) - University of Missouri, Kansas City, MO
MS (Statistics) - University of Missouri, Kansas City, MO
BS (Mathematics) - Sichuan University, China

Research Interests

  • Statistical and machine learning methods for high-dimensional omics data
  • Integrative analysis in multi-omics studies
  • Longitudinal and time series models

Selected Publications

*Indicates corresponding authorship.

Meng G, Pan Y, Tang T, Zhang L, Cui Y, Schumacher F, Wang M, Wang R, He S, Krischer J, Li Q*, Feng H*. imply: improving cell-type deconvolution accuracy using personalized reference profiles. Genome Medicine (Method), 2024. DOI: 10.1186/s13073-024-01338-z (co-corresponding author)

Pan Y, Wang X, Sun J, Liu C, Peng J, Li Q*. Multimodal joint deconvolution and integrative signature selection in proteomics. Communications Biology, 2024. DOI:10.1038/s42003-024-06155-z (Senior and corresponding author)

Plonski N-M, Pan Y, Chen C, Dong Q, Zhang X, Song N, Shelton K, Easton J, Mulder H, Zhang J, Neale G, Walker E, Wang H, Webster R, Brinkman T, Krull KR, Armstrong GT, Ness KK, Hudson MM, Li Q#, Huang I-C#, Wang Z#. Health-Related Quality of Life and DNA Methylation-Based Aging Biomarkers among Survivors of Childhood Cancer. Journal of National Cancer Institute, 2024. DOI: 10.1093/jnci/djae046 (Co-senior author)

Feng H*, Meng G, Lin T, Parikh H, Pan Y, Li Z, Krischer J and Li Q*. ISLET: individual-specific reference panel recovery improves cell-type-specific inference. Genome Biology (Method), 2023, DOI: 10.1186/s13059-023-03014-8 (Senior and co-corresponding author)

Plonski N-M, Chen C, Dong Q, Qin N, Song N, Shelton K, Finch E, Easton J, Mulder H, Zhang J, Neale G; Walker E, Wang H, Krull K, Ness KK, Hudson MM, Robison LL, Li Q, Williams AL, Wang Z. Epigenetic age in peripheral blood among children, adolescent, and adult survivors of childhood cancer. JAMA Network Open, 2023. DOI:10.1001/jamanetworkopen.2023.10325

Ahmed KT, Cheng S, Li Q, Yong J, Zhang W. Incomplete time-series gene expression in integrative study for islet autoimmunity prediction. Briefings in Bioinformatics. 2023. DOI: 10.1093/bib/bbac537.

Stahl M, Li Q, Gragert L, Aronsson C, Lindfors K, Kurppa K, Koletzko S, Ilonen J, Rewers M, Agardh D, Hagopian W, Liu E, and the TEDDY Study Group. Incidence of Pediatric Celiac Disease Varies by Region: Celiac Disease Varies by Region. Am J Gastroenterol, 2022. DOI: 10.14309/ajg.0000000000002056.

Song N, Dong Q, Chen C, Li Q, Mulder H, Plyler E, Easton J, Walker E, Olson S, Neale G, Krull KR, Srivastava DK, Ness KK, Zhang J, Hudson MM, Robison LL, Huang I-C, Wang Z. A Social-epigenomic Investigation in Pulmonary Impairment among Childhood Cancer Survivors. Cancer Communications, 2022, DOI: 10.1002/cac2.12371

Tanvir Ahmed K, Cheng S, Li Q, Yong J, Zhang W. Incomplete time-series gene expression in integrative study for islet autoimmunity prediction. Briefings in Bioinformatics Jan 19;24(1):bbac537, 2023. doi: 10.1093/bib/bbac537

Stahl M, Li Q, Lynch K, Koletzko S, Mehta P, Gragert L, Norris JM, Aronsson CA, Lindfors K, Kurppa K, Ilonen J, Krischer J, Alkolkar B, Ziegler AG, Toppari J, Rewers M, Agardh D , Hagopian W, Lui E. Incidence of Pediatric Celiac Disease Varies by Region: Celiac Disease Varies by Region. Am J Gastroenterol Dec 23, 2022. doi: 10.14309/ajg.0000000000002056

Song N, Dong Q, Chen C, Li Q, Mulder H, Plyler E, Easton J, Walker E, Olson S, Neale G, Krull KR, Srivastava DK, Ness KK, Zhang J, Hudson MM, Robison LL, Huang IC, Wang Z. Social-epigenetic mediators for racial disparities in pulmonary impairment among childhood cancer survivors. Cancer Communications (Lond) Oct 18, 2022. doi: 10.1002/cac2.12371

Dong Q, Song N, Qin N, Chen C, Li Z, Sun X, Easton J, Mulder H, Plyler E, Neale G, Walker E, Li Q, Ma X, Chen X, Huang IC, Yasui Y, Ness KK, Zhang J, Hudson MM, Robison LL, Wang Z. Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer. Genome Medicine Mar 22;14(1):32, 2022. doi: 10.1186/s13073-022-01038-6

Li Q*, Liu X, Yang J, Lernmark A, Hagopian W, Rewers M, She J-X, Toppari J, Ziegler AG, Akolkar B, Krischer JP, and the TEDDY Study Group. Plasma metabolome and circulating vitamins stratified onset age of an initial islet autoantibody and progression to type 1 diabetes: the TEDDY study. Diabetes 2020. DOI:10.2337/db20-0696

Li Q*, Parikh H, Butterworth MD, Lernmark A, Hagopian W, Rewers M, She J-X, Toppar J, Ziegler AG, Akolkar B, Fiehn O, Fan S, Krischer JP, and the TEDDY Study Group. Longitudinal metabolome-wide signals prior to the appearance of a first islet autoantibody in children participating in the TEDDY study. Diabetes 2020. DOI:10.2337/db19-0756

Li Q*, Location Multiplicative Error Models With Quasi Maximum Likelihood Estimation. Journal of Time Series Analysis 2019. DOI:10.1111/jtsa.12513

Li Q, Fisher K, Meng W, Welsh E, Fang B, Haura E, Koomen J, Eschrich S, Fridley BL, Chen YA. GMSimpute: a generalized two-step Lasso approach to impute missing values in label-free mass spectrum analysis. Bioinformatics 2019. DOI: 10.1093/bioinformatics/btz488

Last update: June 2024

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