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Qian Li, PhD
Qian Li, PhD

Qian Li, PhD

Assistant Member, St. Jude Faculty

Departments

Education

Postdoctoral Fellowship - Moffitt Cancer Center, Tampa, FL
Postdoctoral Fellowship - University of Kansas Medical Center, Kansas City, KS
PhD (Statistics) - University of Missouri, Kansas City, MO
MS (Statistics) - University of Missouri, Kansas City, MO
BS (Mathematics) - Sichuan University, China

Research Interests

  • Statistical and machine learning methods for high-dimensional omics data
  • Integrative analysis in multi-omics studies
  • Longitudinal and time series models

Selected Publications

Li Q, Liu X, Yang J, Lernmark A, Hagopian W, Rewers M, She J-X, Toppari J, Ziegler AG, Akolkar B, Krischer JP, and the TEDDY Study Group. Plasma metabolome and circulating vitamins stratified onset age of an initial islet autoantibody and progression to type 1 diabetes: the TEDDY study. Diabetes 2020. DOI:10.2337/db20-0696

Wilson C, Li Q, Gaedigk R, Bi C, de Wildt S, Leeder JS, Fridley BL. Ontogeny related changes in the pediatric liver metabolome. Frontiers in Pediatrics 2020. DOI:10.3389/fped.2020.00549

Li Q, Parikh H, Butterworth MD, Lernmark A, Hagopian W, Rewers M, She J-X, Toppar J, Ziegler AG, Akolkar B, Fiehn O, Fan S, Krischer JP, and the TEDDY Study Group. Longitudinal metabolome-wide signals prior to the appearance of a first islet autoantibody in children participating in the TEDDY study. Diabetes 2020. DOI:10.2337/db19-0756

Li Q, Location Multiplicative Error Models With Quasi Maximum Likelihood Estimation. Journal of Time Series Analysis 2019. DOI:10.1111/jtsa.12513

Li Q, Yu X, Chaudhary R, Slebos RJC, Chung CH, Wang X. lncDIFF: a novel quasi-likelihood method for differential expression analysis of non-coding RNA. BMC Genomics 2019. DOI:10.1186/s12864-019-5926-4

Li Q, Fisher K, Meng W, Welsh E, Fang B, Haura E, Koomen J, Eschrich S, Fridley BL, Chen YA. GMSimpute: a generalized two-step Lasso approach to impute missing values in label-free mass spectrum analysis. Bioinformatics 2019. DOI: 10.1093/bioinformatics/btz488

Li Q, Noel-MacDonnell JR, Koestler DC, Goode EL, Fridley BL. Subject Level Clustering Using a Negative Binomial Model for Small Transcriptomic Studies. BMC Bioinformatics 2018. DOI: 10.1186/s12859-018-2556-9

Abbas-Aghababazadeh F, Li Q, Fridley BL. Comparison of normalization approaches for gene expression studies completed with high-throughput sequencing. PLOS One 2018. DOI: 10.1371/journal.pone.0206312

Fridley BL, Dai J, Raghavan R, Li Q, Winham SJ, Hou X, Weroha SJ, Wang C, Kalli KR, Cunningham JM, Lawrenson K, Gayther SA, Goode EL. Transcriptome Characterization and Comparison of High Grade Serous, Clear cell and Endometrioid Epithelial Ovarian Cancer Tumors. Cancer Epidemiology, Biomarkers & Prevention 2018. DOI: 10.1158/1055-9965.EPI-17-0728

Earp MA, Raghavan R, Li Q, et al., Characterization of fusion genes in common and rare epithelial ovarian cancer histologic subtypes. Oncotarget 2017. DOI:10.18632/oncotarget.16781.

Last update: April 2021