Mary E. (Beth) McCarville, MD
Mary E. (Beth) McCarville, MD

Mary E. (Beth) McCarville, MD

Member, St. Jude Faculty



BS – University of Iowa, Iowa City, IA (1986)
MD – University of Iowa College of Medicine, Iowa City, IA (1990)
RT – Iowa Methodist Medical Center, School of Radiologic Technology, Des Moines, IA (1977)

Honors & Awards

  • 2009-2010, 2011-2012 Recognized in Best Doctors in America®
  • 2011 Certificate of Merit from the Society for Pediatric Radiology presented at the International Paediatric Radiology Congress, May 27th-31st, 2011, London, UK, for the scientific exhibit: Ultrasound and Magnetic Resonance Imaging Features of Unusual Ocular Disease in Children with Clinical and Pathological Correlation. McCarville MB, Kaste SC, Wilson W.
  • 2005 Caffey Award for Basic Science Research from the Society for Pediatric Radiology, presented at the 2005 annual meeting, for the oral presentation: Quantitative Measurement of Microbubble Ultrasound Contrast Agent Flow To Assess the Efficacy of Angiogenesis Inhibitors In Vivo. McCarville B, Streck C, Li C-S, Davidoff A.
  • 2004 Certificate of Merit from the Society for Pediatric Radiology presented at the 2004 annual meeting, for the scientific exhibit: Not all 18FDG-Avid Sites Represent Active Disease in Pediatric Hodgkin’s. Kaste SC, Howard S, McCarville MB, Krasin MJ, Hudson MM.

Research Interests

  • Ultrasound

Selected Publications

McCarville MB, Roebuck DJ. Diagnosis and staging of hepatoblastoma: imaging aspects. Pediatr Blood Cancer June 7, 2012.

Qaddoumi I, Billups CA, Tagen M, Stewart CF, Wu J, Helton K, McCarville MB, Merchant TE, Brennan R, Free TM, Given V, Haik BG, Rodriguez-Galindo C, Wilson MW. Topotecan and vincristine combination is effective against advanced bilateral intraocular retinoblastoma and has manageable toxicity. Cancer April 19, 2012.

McCarville MB, Hillenbrand CM, Loeffler RB, Smeltzer MP, Song R, Li CS, Hankins JS. Comparison of whole liver and small region-of-interest measurements of MRI liver R2* in children with iron overload. Pediatr Radiol March 24, 2010.

Kaste SC, Waszilycsak G, McCarville MB, Daw NC. Estimation of potential cancer incidence in pediatric thallium-201 imaging. Am J Roentgenol 2009 (in press).

Karplus G, Krasin MJ, Rodriguez-Galindo C, McCarville B, Jenkins J, Rao B, Spyridis G, Spunt SL. Retrospective study of the surgical management and outcome of non-rhabdomyosarcoma soft tissue sarcomas of the groin and axilla in children. J Ped Surg 2009 (in press).

Furman WL, Navid F, Daw NC, McCarville MB, McGregor LM, Sheri L. Spunt SL, Rodriguez-Galindo C, Panetta JC, Crews KR, Wu J, Gajjar AJ, Houghton PJ, Santana VM, Stewart CF. A tyrosine kinase inhibitor enhances the bioavailability of oral irinotecan in pediatric patients with refractory solid tumors. J Clin Oncol 2009 (in press).

Hankins JS, McCarville MB, Loeffler RB, Onciu M, Smeltzer MO, Hoffer FA, Li C-S, Wang WC, Ware RE, Hillenbrand CM. R2* magnetic resonance imaging of the liver in patients with iron overload.Blood 113:4853-4855, 2009.

Karplus G, McCarville MB, Smeltzer MP, Spyridis G, Rao BN, Davidoff AM, Li C-S, Shochat S. Should contralateral exploratory thoracotomy be advocated for children with osteosarcoma and early unilateral pulmonary metastases? J Ped Surg Apr;44(4):665-71, 2009.

McCarville MB, Monu NC, Smeltzer MP, Li C-S, Laningham FH, Morris EB, Shulkin BL. PET-CT of the normal spinal cord in children. Aca Radiol May 7, 2009 (Epub ahead of print).

Furman WL, Navid F, McCarville MB, Daw NC, McGregor L, Rodriguez-Galindo C, Panetta JC, Crews KR, Billups C, Wu J, Gajjar AJ, Houghton PJ, Santana VM, Stewart CF.  Gefinib enhances the oral bioavailability of irinotecan in pediatric patients with refractory solid tumors.J Clin Oncol 2009 (in press).

Rodriguez-Galindo C, Jeng M, Khuu P, McCarville MB, Sima J. Clofarabine in refactory Langerhans cell histiocytosis.Pediatr Blood Cancer Nov;51(5):703-6, 2008.

Sims TL. Hamner JB, Bush RA, Fischer PE, Kim SU, Aboody KS, McCarville B, Danks MK, Davidoff AM. Neural progenitor cell-mediated delivery of osteoprotegerin limits disease progression in a pre-clinical model of neuroblastoma bone metastasis. J Pediatr Surg Jan;44(1):204-10, 2009.

Kasow KA, Krueger J, Srivastava DK, Barfield R, Leung W, Hussain I, McCarville MB, Hale GA. Clinical utility of computed tomography screening of chest, abdomen, and sinuses before hematopoietic stem cell transplantation: The St. Jude experience. Biol Blood Marrow Transplant Apr;15(4):490-5, 2009.

Navid F, Willert JR, McCarville MB, Furman W, Watkins A, Roberts W, Daw NC. Combination of gemcitabine and docetaxel in treatment of children and young adults with refractory bone sarcoma.Cancer Jul 15;113(2):419-25, 2008.

Dickson PV, Sims TL, Streck CJ, McCarville MB, Santana VM, McGregor LM, Furman WL, Davidoff AM. Avoiding misdiagnosing neuroblastoma as Wilms tumor. J Pediatr Surg Jun;43(6):1159-63, 2008.

Hankins JS, Fortner G, McCarville MB, Smeltzer MP, Wang WC, Li C-S, Ware RE. The natural history of conditional transcranial Doppler flow velocities in children with sickle cell anemia. British Jo Hematol May:142; 94–99, 2008.

Shulkin BL, Goodin GS, McCarville MB, Kaste SC, Krasin MJ, Hudson MM, Metzger M. Bone and FDG PET/CT scanning for the assessment of osseous involvement in Hodgkin lymphoma in children and young adults. Leuk Lymph 2009 (in press).

McCarville MB, Goodin GS, Fortner G, Day S, Li C-S, Adam R, Wang W. Evaluation of a comprehensive transcranial Doppler screening program for children with sickle cell anemia. Pediatr Blood and Cancer 50:8 18-821, 2008.

Dickson PV, Hamner JB, Sims TL, Fraga CH, Ng CYC, Rajasekeran S, McCarville MB, Hagedorn NL, Stewart CF, Davidoff AM. Bevacizumab-induced transient remodeling of the vasculature in neuroblastoma xenografts results in improved delivery and efficacy of systemically administered chemotherapy. Clin Cancer Res July; 3( l3):3942-50, 2007.

McCarville MB, Hoffer FA, Adelman CS, Khoury JD, Li C, Skapek SX. Magnetic resonance imaging and biological behavior of desmoid tumor in children. Am J Roentgenol 189;633-640, 2007.

Absalon MJ, McCarville MB, Liu T, Santa V, Navid F. Pulmonary nodules discovered during the initial evaluation of pediatric patients with bone and soft-tissue sarcoma. Pediatr Blood and Cancer 2008 (in press).

Hankins JS, Helton KJ, McCarville MB, Li C-S, Wang WC, Ware RE. Preservation of spleen and brain function in children with sickle cell anemia treated with hydroxyurea. Pediatr Blood Cancer Feb;50(2):293-7, 2008.

Dickson PV, Hall MM, Hargrove PW, Ng CYC, Zhou J, McCarville MB, Davidoff AM. In vivo bioluminescence imaging for early detection and monitoring of disease progression in a murine model of neuroblastoma. Jo Pediatr Surgery Ju1;42(7):1172-9, 2007.

Goodin GS, McCarville MB, Thibodeau SN, Skapek SX, Khoury JD, Spunt SL. Prolactinoma as the first manifestation of Gardner’s syndrome. Ped Blood and Cancer Feb;50(2):409-12, 2008.

Krasin MJ, Xiong X, Reddick WE, Ogg RJ, Hoffer FA, McCarville MB, Kaste SC, Spunt SS, Navid F, Davidoff AM, Zhang L, Kun LE, Merchant TE. A model predicting radiation-induced quantitative changes in the magnetic resonance signal characteristics in the muscle of children over time.Magnetic Resonance Imaging 24(10):1319-1324, 2006.

Wagner LM, McAllister N, Goldsby RE, Rausen AR, McNall-Knapp R, McCarville MB, Albritton K. Temozolomide and intravenous irinotecan for treatment of advanced Ewing sarcoma. Ped Blood and Cancer  48:132-139, 2007.

McCarville MB, Barton EH, Cameron J, Xiong X, Daw NC, Wu S, Glass JO, Reddick WE. The etiology and clinical significance of the thallium donut sign in pediatric osteosarcoma of the extremity. Am J Roentgen 188(2):572-578, 2007.

Show More

Goodin GS, Shulkin BL, Kaufman RA, McCarville MB. PET/CT characterization of fibro-osseous defects in children: FDG uptake can mimic metastatic disease. Am J Roentgenol Oct;187(4):1124-8, 2006.

Dickson PV, Hamner JB, Cauthen LA, Ng YC, McCarville MB, Davidoff AM. Efficacy of zoledronate against neuroblastoma. Surgery Aug;140(2):227-35, 2006.

Daw NC, Jenkins JJ, McCarville MB, Rao BN, Neel MN. Polymethylmethacrylate lung embolus after limb-salvage surgery for osteosarcoma. Clin Orthop Relat Res July;448:252-256, 2006.

Daw NC, Billups CA, Rodriguez-Galindo C, McCarville MB, Rao BN, Cain AM, Jenkins JJ, Neel MD, Meyer WH. Metastatic osteosarcoma: results of two consecutive therapeutic trials at St. Jude Children's Research Hospital. Cancer Jan 15;106(2):403-412, 2006.

McCarville MB, Lederman H, Santana VM, Daw NC, Shochat SJ, Li C-S, Kaufman RA. Distinction of benign from malignant pulmonary nodules by helical chest CT in children with malignant solid tumors. Radiology May;239(2):514-20, 2006.

Metzger ML, Howard SC, Hudson MM, Gow KW, Li C-S, Krasin MJ, Merchant T, Kun L, Shelso J, Pui C-H, Shochat SJ, McCarville MB. Natural history and management of thyroid nodules in survivors of pediatric hodgkin lymphoma. Pediatr Blood Cancer Mar;46(3):314-9, 2006.

McCarville MB, Kao SC. Imaging recommendations for malignant liver neoplasms in children.Pediatric Blood and Cancer 46(1):2-7, 2006.

McCarville MB, Streck C, Dickson PV, Li C-S, Nathwani A, Davidoff A. Quantitative, non-invasive assessment of intratumoral blood flow using contrast enhanced grayscale ultrasonography to evaluate the efficacy of angiogenesis inhibitors in a murine neuroblastoma model. Radiology Jul;240(1):73-81, 2006.

Last update: June 2012