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Richard S. Finkel, MD

Member, St. Jude Faculty

Director, Center for Experimental Neurotherapeutics

Director, Pediatric Translational Neuroscience Clinical Research Network, Powered by St. Jude

George J. Pedersen Endowed Chair in Neurotherapeutics

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Contact Information

Richard S. Finkel, MD

Center for Experimental Neurotherapeutics

MS 760

St. Jude Children's Research Hospital

262 Danny Thomas Place

MemphisTN 38105-3678

Quick Facts

Finkel was elected as a Member of the Association of American Physicians in 2025 in recognition of his outstanding contributions to the medical field and a commitment to fostering innovation and collaboration among physician scientists.

Education

BA (Chemistry) - Washington and Jefferson College, Washington, Pennsylvania Internship and Residency (Pediatrics) - Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts Neurology Fellowship (Neurology) - Children’s, Beth Israel, Brigham and Women’s and VA Hospitals, Harvard Medical School, Boston, Massachusetts MD - Washington University, St. Louis, Missouri

Honors & Awards

  • 2017  Bengt Hagberg memorial lecture, Swedish Neuropediatric Society
  • 2018  Sidney Carter Child Neurology Award, American Academy of Neurology
  • 2019  Co-awardee of the International Prize for Translational Neuroscience of the Gertrud Reemtsma Foundation of the Max Plank Institute

Research Interests

  • Participation in clinical trials with investigational drugs for pediatric neurologic and metabolic diseases
  • Development of outcome measures, biomarkers, and clinical trial design for pediatric neurologic diseases
  • Understanding the trajectories of change in pediatric neuromuscular diseases: spinal muscular atrophy, Duchenne muscular dystrophy, and Charcot-Marie-Tooth inherited neuropathies.

Clinical Trials

Closed
DYNEDMD: Measuring Safety and How Well DYNE-251 Works in Boys with Duchenne Muscular Dystrophy

Study goal:

The main goal of this study is to see if DYNE-251 is safe to use in young males with DMD. Researchers also want to find out how well DYNE-251 treats the disease and how it affects the body in other ways.

Age:

Male, age 4 to 16 years old

Closed
FACOMS: Friedreich's Ataxia Clinical Outcome Measures

Study goal:

To better understand how Friedreich’s ataxia progresses and to develop tests that can be used in other clinical trials to measure changes in the disease over time.

Age:

Birth to 22 years old

Recruiting
INC: Pediatric Study of Charcot-Marie-Tooth Disease

Study goal:

This long-term study aims to better understand the genetic causes of Charcot-Marie-Tooth disease (CMT) and to learn how different forms of the rare hereditary disease affect people over time.

Age:

Birth to 22 years

Recruiting
ML43225: Spinal Muscular Atrophy Muscle Response Study

Study goal:

To study how different SMA drugs affect muscles and nerve cells and to study the use of MRI to track muscle changes.

Age:

5-20 years old

Closed
SAPPHIRE: Efficacy and Safety of Apitegromab in Patients with Spinal Muscular Atrophy Receiving Nusinersen or Risdiplam Therapy

Study goal:

This study aims to find out if the drug apetigromab is a safe and effective treatment when used along with the standard treatment for children with spinal muscular atrophy type 2 or 3.

Age:

Between 2 and 21 years old

Open, not recruiting
STEER: Clinical Trial on Use of Intrathecal Zolgensma (OAV101) to Treat Spinal Muscular Atrophy in Children and Teens

Study goal:

To investigate the safety, tolerability, and efficacy of the gene therapy OAV101 (Zolgensma®) delivered intrathecally in treatment-naïve SMA Type 2 patients between ages 2 and 18 with 2-4 copies of SMN2.

Age:

2 years to 17 years

Recruiting
UNIFAI: A Natural History Study of Friedreich’s Ataxia

Study goal:

To collect data about how Friedreich’s ataxia progresses over time and affects the daily life of patients.

Age:

Any

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