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Richard S. Finkel, MD

Member, St. Jude Faculty

Director, Center for Experimental Neurotherapeutics

George J. Pedersen Endowed Chair in Neurotherapeutics

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Contact Information

Richard S. Finkel, MD

Center for Experimental Neurotherapeutics

MS 760

St. Jude Children's Research Hospital

262 Danny Thomas Place

MemphisTN 38105-3678

Quick Facts

Finkel was elected as a Member of the Association of American Physicians in 2025 in recognition of his outstanding contributions to the medical field and a commitment to fostering innovation and collaboration among physician scientists.

Education

BA (Chemistry) - Washington and Jefferson College, Washington, Pennsylvania Internship and Residency (Pediatrics) - Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts Neurology Fellowship (Neurology) - Children’s, Beth Israel, Brigham and Women’s and VA Hospitals, Harvard Medical School, Boston, Massachusetts MD - Washington University, St. Louis, Missouri

Honors & Awards

  • 2017  Bengt Hagberg memorial lecture, Swedish Neuropediatric Society
  • 2018  Sidney Carter Child Neurology Award, American Academy of Neurology
  • 2019  Co-awardee of the International Prize for Translational Neuroscience of the Gertrud Reemtsma Foundation of the Max Plank Institute

Research Interests

  • Participation in clinical trials with investigational drugs for pediatric neurologic and metabolic diseases
  • Development of outcome measures, biomarkers, and clinical trial design for pediatric neurologic diseases
  • Understanding the trajectories of change in pediatric neuromuscular diseases: spinal muscular atrophy, Duchenne muscular dystrophy, and Charcot-Marie-Tooth inherited neuropathies.

Clinical Trials

Closed
DYNEDMD: Measuring Safety and How Well DYNE-251 Works in Boys with Duchenne Muscular Dystrophy

Study goal:

The main goal of this study is to see if DYNE-251 is safe to use in young males with DMD. Researchers also want to find out how well DYNE-251 treats the disease and how it affects the body in other ways.

Age:

Male, age 4 to 16 years old

Closed
FACOMS: Friedreich's Ataxia Clinical Outcome Measures

Study goal:

To better understand how Friedreich’s ataxia progresses and to develop tests that can be used in other clinical trials to measure changes in the disease over time.

Age:

Birth to 22 years old

Recruiting
INC: Pediatric Study of Charcot-Marie-Tooth Disease

Study goal:

This long-term study aims to better understand the genetic causes of Charcot-Marie-Tooth disease (CMT) and to learn how different forms of the rare hereditary disease affect people over time.

Age:

Birth to 22 years

Recruiting
ML43225: Spinal Muscular Atrophy Muscle Response Study

Study goal:

To study how different SMA drugs affect muscles and nerve cells and to study the use of MRI to track muscle changes.

Age:

5-20 years old

Closed
SAPPHIRE: Efficacy and Safety of Apitegromab in Patients with Spinal Muscular Atrophy Receiving Nusinersen or Risdiplam Therapy

Study goal:

This study aims to find out if the drug apetigromab is a safe and effective treatment when used along with the standard treatment for children with spinal muscular atrophy type 2 or 3.

Age:

Between 2 and 21 years old

STEER: Clinical Trial on Use of Intrathecal Zolgensma (OAV101) to Treat Spinal Muscular Atrophy in Children and Teens

Study goal:

To investigate the safety, tolerability, and efficacy of the gene therapy OAV101 (Zolgensma®) delivered intrathecally in treatment-naïve SMA Type 2 patients between ages 2 and 18 with 2-4 copies of SMN2.

Age:

2 years to 17 years

Recruiting
UNIFAI: A Natural History Study of Friedreich’s Ataxia

Study goal:

To collect data about how Friedreich’s ataxia progresses over time and affects the daily life of patients.

Age:

Any

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