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John D. Schuetz, PhD
John D. Schuetz, PhD

Education

PhD – Medical College of Virginia, Richmond (1984)

Honors & Awards

  • 2022-2025 President International Transmembrane Transporter Society
  • 2024 Elected to Chair of AAAS Pharmaceutical Sciences - Section S
  • 2021 ASPET Fellow
  • 2020 Elected Vice-President International Transmembrane Transporter Society
  • 2017-2018 Charles W. Gowdey Distinguished Lecture
  • 2017 President, ASPET
  • 2016 Chair, ASPET Financial Task Force
  • 2016 President-elect, ASPET
  • 2016 The Ohio State University Distinguished Lecturer
  • 2015 ASPET Toxicology Career Development Award

Research Interests

  • Role of ABC transporters in response to chemotherapy
  • Biological function of ABC transporters
  • Regulation of ABC transporters
  • Metabolism

Selected Publications

Tomoka Gose, Sourav Das, Yao Wang,  Heather Aitken, John Lynch, Yu Fukuda, Medb Wills. Stefanie Baril, Robert C. Ford, Megan O’Mara, Anang Shelat, and John D. Schuetz. The net electrostatic potential and hydration of ABCG2 affects substrate transport. Nature Communications Aug 18, 2023. (PMID: 37596258)

John Lynch, Yao Wang, Yuxin Li Kanisha Kavdia, Yu Fukuda, Sabina Ranjit, Camenzind G. Robinson, Christy R. Grace, Youlin Xia, Junmin Peng, and John D. Schuetz. PPIX-binding Proteins Reveal Porphyrin Synthesis and Ferroptosis Link. Communications Biology June 24;Article number 673, 2023.

Sabina Ranjit, Jingwen Zhu, Yao Wang, Satish B. Cheepala, Erin G. Schuetz, Woo Jung Cho, Xu Besi, Camenzind G. Robinson, Gang Wu, Anjaparavanda P. Naren, John D. Schuetz. ABCC4 Protects Megakaryocytes against 6-Mercaptopurine Induced Cytotoxicity and Impacts Megakaryopoiesis. Drug Resist Updates. Jan 2024 (PMID: 37988981)

Pitre A, Ge Y, Wenwei L, Wang Y, Fukuda Y, Temirov J, Phillips AP, Peters J, Fan Y, Ma J, Nourse A, Sinha C, Lin H, Kriwacki R, Downing J, Gruber T, Centonze V, Naren A, Chen T, Schuetz JD*. An unexpected protein interaction facilitates hemtopoietic progenitor self-renewal and drug resistance. Nat Commun. 2017 Nov 16; (8)1:1547.(PMCID: PMC5691054) (*corresponding author)

Last update: April 2024

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