David J. Solecki, PhD
David J. Solecki, PhD

David J. Solecki, PhD

Associate Member, St. Jude Faculty



BS – Rochester Institute of Technology, Rochester, NY (1992)
PhD (Molecular and Cellular Biology) – SUNY at Stony Brook, NY (1999)

Research Interests

  • Molecular and cellular mechanisms regulating neuronal motility
  • The interplay between neuronal differentiation and neuronal polarity signaling
  • The centrosome as a focal point to coordinate cellular polarity
  • Time-lapse microscopy as a tool to unlock the cell biology of neural development
  • Cerebellar development

Selected Publications

Solecki DJ. Sticky situations: recent advances in control of cell adhesion during neuronal migration. Curr Opin Neurobiol May 2, 2012.

Famulski JK, Trivedi N, Howell D, Yang Y, Tong Y, Gilbertson R, Solecki DJ. Siah Regulation of Pard3A Controls Neuronal Cell Adhesion During Germinal Zone Exit. Science 330(6012):1834-8, 2010. PMID: 21109632 *1 Scopus Citation.

Trivedi N, Solecki DJ. Neuronal migration illuminated: A look under the hood of the living neuron. Cell Adh Migr 5(1):42-7, 2011. PMID: 20935494.

Kerekes RA, Gleason SS, Trivedi N, Solecki D. Automated method for tracing leading and trailing processes of migrating neurons in confocal image sequences. Proceedings of the SPIE 7623:76233T-76233T-10, 2010.

Kerekes R, Gleason S, Trivedi N, Solecki D. Automated 4-D Tracking of Centrosomes in Sequences of Confocal Image Stacks. Proc IEEE Eng Med Biol Soc 6994-7, 2009. *3 Scopus Citations.

Solecki DJ, Trivedi N, Govek E, Kerekes R, Gleason S, Hatten ME. Myosin II motors and f-actin dynamics drive the coordinated translocation of the centrosome and soma during CNS glial-guided neuronal migration. Neuron 63(1):63-80, 2009. *24 Scopus Citations, Evaluated by Faculty of 1000.

Solecki DJ, Model L, Gaetz J, Kapoor T, Hatten ME. Par6a signaling controls glial-guided neuronal migration. Nature Neuroscience 7(11):1195-203, 2004. *109 Scopus Citations.
*Cover art November Nature Neuroscience 2004 issue.
*Commentary of this article: Samuels BA and Tsai LH. Nucleokinesis Illuminated. Nature Neuroscience 7(11):1169-70, 2004.
*Evaluated by Faculty of 1000.

Solecki DJ, Liu XL, Tomoda T, Fang Y, Hatten, ME. Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation. Neuron 31(4):557-68, 2001. *160 Scopus Citations.

Last update: May 2012

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