Skip to main content
Georgios Christakopoulos, MD
Georgios Christakopoulos, MD

Georgios Christakopoulos, MD

Instructor, St. Jude Faculty

Departments

Education

  • Postdoctoral Research Fellow (Hematology) - St Jude Children’s Research Hospital, Memphis, TN
  • Postdoctoral Research Fellow (Blood & Marrow Transplantation) - University of Minnesota, Minneapolis, MN
  • Postdoctoral Research Fellow (Hematology) - Cincinnati Children’s Hospital, Cincinnati, OH           
  • Postdoctoral Research Fellow (Cardiology) - University of Texas Southwestern Medical Center, Dallas, TX
  • Resident (Pediatrics - Physician Scientist Training Program (PSTP), Integrated Research Pathway) - University of Minnesota, Minneapolis, MN
  • Clinical Fellow (Pediatric Hematology, Oncology & BMT) - St Jude Children’s Research Hospital, Memphis, TN
  • MD - University Athens School of Health Sciences, Athens, Greece

Honors & Awards

  • 2023 ASH Research Training Award for Fellows (RTAF) Grant (2nd year)
  • 2022 ASH Research Training Award for Fellows (RTAF) Grant
  • 2021 Abstract Achievement Award, American Society of Hematology (ASH) Annual Meeting, Atlanta, GA
  • 2019  Abstract Achievement Award, American Society of Hematology (ASH) Annual Meeting, Orlando, FL
  • 2019 ASH HONORS Award Grant
  • 2016 Abstract Achievement Award, American Society of Hematology,ASH Annual Meeting, San Diego, CA
  • 2013 “Summa Cum Laude” Medical School Academic excellence scholarship: “Latsis Foundation” 

Research Interests

  • Development of genome editing strategies to cure β-thalassemia
  • Investigating the role of ULK1-dependent non-canonical autophagy in mediating the pathophysiology of b-thalassemia
  • Non-coding RNAs in red blood cell formation, including microRNAs and long non-coding RNAs

Selected Publications

Keith J*, Christakopoulos GE*, Fernandez AG, Yao Y, et al. Loss of miR-451 alleviates b-thalassemia by stimulating ULK1-mediated autophagy of free α-globin. Blood Online ahead of print June 20, 2023. PMID: 37339583 (*equally contributed first authors)

Christakopoulos GE, Walker KN, Wang L., et al. Clinical Features and Cytoreduction Therapy in Children with Newly Diagnosed AML & Hyperleukocytosis. Cancer Epub Mar 21, 2023. PMID: 36943896

Christakopoulos GE, Telange R, Yen J, Weiss MJ. Gene therapy and gene editing for β-thalassemia. Hematology/Oncology Clinics Journal Apr;37(2):433-447, 2023. PMID: 36907613

Feng R, Mayuranathan T, Huang P, Doerfler PA, LiY, Yao Y, Zhang J, Palmer LE, Xu P, Mayberry K, Christakopoulos GE, Wright S, Li C et al. Activation of γ-globin expression by hypoxia-inducible factor 1a. Nature Epub Oct 12, 2022. PMID: 36224385

Crossley M, Christakopoulos GE, Weiss MJ. Effective therapies for Sickle Cell Disease: are we there yet? Trends in Genet Aug 2022. Online ahead of print. PMID: 35934593

Chakraborty A, Beasley G, Martinez H, Jesudas R, Anton-Martin P, Christakopoulos G, Kramer J. Use of Selumetinib for refractory pulmonary and gastrointestinal bleed with Noonan’s Syndrome. Pediatrics Oct 2022. PMID: 36082608

Christakopoulos GE, DeFor TE, Hage S, Wagner JE, et al. Phase I dose finding, safety and tolerability trial of Promiplostim to Improve Platelet Recovery after UCB Transplantation. Transplant Cell Ther Jun 2021. Epub 2021 Mar 2. PMID: 33785364

Christakopoulos GE, Kobe C, Flesch S, Lee J, et al. Personalized Clinical Research: Childhood Cancer Survivor and Parent Preferences for Research Participation. J of Clin Oncol Practice Dec 2020. Epub 2020 Oct 2. PMID: 33006912

Risinger M, Christakopoulos GE, Schultz CL, et al. Hereditary elliptocytosis-associated alpha-spectrin mutation p.L155dup as a modifier of sickle cell disease severity. Pediatr Blood Cancer Feb 2019. PMID: 30393954

Christakopoulos GE, Christopoulos G, Karmpaliotis D, et al. Predictors of Excess Patient Radiation Dose During Chronic Total Occlusion Coronary Intervention: Insights from a Contemporary Multicenter Registry. Can J Cardiol Apr 2017. PMID: 28169091

Christakopoulos GE, Karacsonyi J, Danek BA, et al. Near-Infrared Spectroscopy Analysis of Coronary Chronic Total Occlusions. J Invasive Cardiol Dec 2016.  PMID: 27922805

Spaedy E, Christakopoulos GE, Tarar MN, et al. Accuracy of remote chest X-ray interpretation using Google Glass technology. Int J Cardiol Sep 15;219:38-40, 2016. Epub 2016 May 25. PMID: 27262231

Stetler J, Resendes E, Martinez-Parachini JR, Patel K, Amsavelu S, Christakopoulos GE, Rangan BV, et al. Hands-free zoom and pan technology improves the accuracy of remote electrocardiogram interpretation using Google Glass. Int J Cardiol Feb 1, 2016. PMID: 26657610

Jabbar A, Christopoulos G, Karatasakis A, Jeroudi OM, Christakopoulos GE, et al. Impact of Chronic Total Occlusion Revascularization Attempts on Subsequent Clinical Outcomes. J Invasive Cardiol Dec 2016. PMID: 27922810

Amsavelu S, Christakopoulos GE, Karatasakis A, et al. Impact of Crossing Strategy on Intermediate-term Outcomes After Chronic Total Occlusion Percutaneous Coronary Intervention. Can J Cardiol Oct, 2016. PMID: 27006316

Christopoulos G, Papayannis AC, Alomar M, Christakopoulos GE, Kotsia A, et al. Determinants of operator and patient radiation exposure during cardiac catheterization: Insights from the RadiCure (RADIation reduction during cardiac catheterization using real-time monitoring) trial. Catheter Cardiovasc Interv Dec 2016. PMID: 26707858

Stetler J, Karatasakis A, Christakopoulos GE, Tarar MN, et al. Impact of crossing technique on the incidence of periprocedural myocardial infarction during chronic total occlusion percutaneous coronary intervention. Catheter Cardiovasc Interv Jul 2016. PMID: 27014962

Christakopoulos GE, Karmpaliotis D, Alaswad K, et al. Contrast utilization During Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from a Contemporary Multicenter Registry. J Invasive Cardiol Jul 2016. PMID: 27342206

Patel KS, Christakopoulos GE, Karatasakis A, Danek BA, et al. Prospective Evaluation of the Impact of Side-Holes and Guide-Catheter Disengagement From the Coronary Ostium on Fractional Flow Reserve Measurements. J Invasive Cardiol Aug 2016. PMID: 27101970

Christopoulos G, Papayannis AC, Alomar M, Christakopoulos GE, et al. Determinants of operator and patient radiation exposure during cardiac catheterization: Insights from the RadiCure (RADIation reduction during cardiac catheterization using real-time monitoring) trial. Catheter Cardiovasc Interv Dec 2016. PMID: 26707858

Christakopoulos GE, Karmpaliotis D, Alaswad K, et al. Contrast utilization During Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from a Contemporary Multicenter Registry. J Invasive Cardiol Jul 2016. PMID: 27342206

Christopoulos G, Makke L, Christakopoulos G, et al. Optimizing radiation safety in the cardiac catheterization laboratory: a practical approach. Catheter Cardiovasc Interv Feb 2016. PMID: 26526181

Pokala NR, Menon RV, Patel SM, Christopoulos G, Christakopoulos GE, Kotsia AP, et al. Long-term outcomes with first- vs. second- generation drug-eluting stents in saphenous vein graft lesions. Catheter Cardiovasc Interv Jan 2016. PMID: 26033073

Christopoulos G, Kandzari D, Yeh RW, Jaffer FA, Karpaliotis D, Wyman MR, Alaswad K, Lombardi W, Grantham JA, Moses J, Christakopoulos G, et al. Development and Validation of a Novel Scoring System for Predicting Technical Success of Chronic Total Occlusion Percutaneous Coronary Interventions: The Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS CTO) score. JACC Cardiovasc Interv Jan 2016. PMID: 26762904

Nguyen-Trong PK, Rangan BV, Karatasakis A, Danek BA, Christakopoulos GE, et al. Predictors and Outcomes of Side-Branch Occlusion in Coronary Chronic Total Occlusion Interventions. J Invasive Cardiol Apr 2016. PMID: 26773239

Last update: August 2023

Close