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Amber D'Souza, MD

Amber D'Souza, MD

  • Clinic Physician



Fellowship - Cincinnati Children's Hospital Medical Center
Residency - Children's Hospital of Pittsburgh
MD - The Ohio State University College of Medicine
BS - The Ohio State University


  • General Pediatrics 2015

Professional Memberships

  • American Academy of Pediatrics
  • American Society of Pediatric Hematology & Oncology
  • American Society of Clinical Oncology

Clinical Interests

  • Molecular mechanisms of liver cancer and biology of high risk disease
  • Targeted therapy for treatment of aggressive pediatric liver cancer
  • Heterogeneity in pediatric hepatocellular carcinoma
  • Patterns of relapse in hepatoblastoma

Selected Publications

D’Souza AM, Shah R, Towbin AJ, Gupta A, Alonso M, Nathan JD, Bondoc A, Tiao G, Geller JI. Surgical Management of Children and Adolescents with Upfront Completely Resected Hepatocellular Carcinoma. Pediatr Blood Cancer July, 2018. Epub ahead of print.

D’Souza AM, Jiang Y, Cast A, Valanejad L, Wright M, Lewis K, Kumbaji M, Shah S, Smithrud D, Shin S, Timchenko NA. Gankyrin Promotes Tumor Suppressor Degradation to Drive Hepatocyte Proliferation. Cell Mol Gastroenterol Hepatol May 2018 (in press).

Valanejad L, Lewis K, Wright M, Jiang Y, D’Souza AM, Karns R, Sheridan R, Gupta A, Bove K, Witte D, Geller J, Tiao G, Nelson DL, Timchenko L , Timchenko N. FXR-Gankyrin Axis is involved in development of Pediatric Liver Cancer. Carcinogenesis July;38(7):738-747, 2017.

D’Souza AM, Mark J, Demarcantonio M, Leino D, Sisson R, Geller JI. Pediatric laryngeal carcinoma in a heterozygous carrier of Fanconi anemia. Pediatr Blood Cancer Epub Jan 31, 2017.

Shen HM, D’Souza AM, Green IF, Pohar KS, Mortazavi A, Zynger DL. Does Amount of Variant Differentiation and Mitotic Rate in Bladder Cancer Change with Neoadjuvant Chemotherapy and Can These Features Be Used to Predict Response? Human Pathology Sept;46(9):1367-75, 2015.

D’Souza AM, Phillips GS, Pohar KS, Zynger DL. Clinicopathologic Characteristics and Overall Survival in Cystectomy Patients with Bladder Cancer Involving the Lower Gastrointestinal Tract. Virchows Archiv Dec;463(6):811-18, 2013.

D’Souza AM, Pohar KS, Arif T, Geyer S, Zynger DL. Retrospective analysis of survival in muscle-invasive bladder cancer: impact of pT classification, node status, lymphovascular invasion, and neoadjuvant chemotherapy. Virchows Archiv Oct;461(4):467-74, 2012.

Last update: October 2018