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Noel M. Delos Santos, MD

  • Consulting Physician, Nephrology
  • Associate Professor of Pediatrics, University of Tennessee Health Science Center



MD – University of Mississippi, University, MS
Internship and Residency – University of Mississippi Medical Center-Blair E. Baston Hospital for Children, Jackson, MS
Fellowship (Pediatric Nephrology) – University of Tennessee Health Science Center; Le Bonheur Children’s Medical Center; St. Jude Children’s Research Hospital; The Med Newborn Center, Memphis, TN
Fellowship (Pharmacology) – National Institutes of Health Individual Research Fellowship in Beta Adrenergic Receptor Signal Transduction (Ruth L. Kirschstein NRSA), University of Tennessee Health Science Center

Clinical Interests

  • Pediatric Nephrology

Selected Publications

Davidoff AM, Interiano RB, Wynn L, Delos Santos N, Dome JS, Green DM, Brennan RC, McCarville MB, Krasin MJ, Kieran K, Williams MA. Ann Surg (2015) 262 (4): 570-6.

Interiano RB, Delos Santos N, Huang S, Srivastava DK, Robison LL, Hudson MM, Green DM, Davidoff AM. Renal function in survivors of nonsyndromic Wilms tumor treated with unilateral radical nephrectomy. Cancer (2015) 121 (14): 2449-56.

Ledet D, Delos Santos NM, Khan R, Gaijar A, Broniscer A. Central neurogenic hyperventilation and renal tubular acidosis in children with pontine gliomas. Neurology (2014) 82, 1099-100.

Sheth P, Delos Santos N, Seth A, LaRusso NF, Rao RK. 'Lipopolysaccharide disrupts tight junctions in cholangiocyte monolayers by a c-Src, TLR4, and LBP­dependent mechanism. American Journal of Physiology (2007) Apr; Epub 2007.

Hastings MC, Delos Santos NM, Wyatt RJ. Renal survival in pediatric patients with lgA nephropathy. Pediatric Nephrol (2007) Feb;22(2): 317-8.

Zeitoun 0, Delos Santos NM, Gardner LA, White SW, Bahouth SW. Mutagenesis within helix 6 of the human beta-1-adrenergic receptor identifies Lysine324 as a residue involved in imparting the high-affinity binding state of agonists. Mol Pharmacol (2006) Sep;70(3):838-50. Epub 2006.

Delos Santos NM, Gardner LA, White SW, Bahouth SW. Characterization of the residues in helix eight of the human beta-I adrenergic receptor that are involved in coupling the receptor to G-proteins. Journal of Biological Chemistry (2006) May; 281 (18): 12896-12907.

Lau KL, Delos Santos NM. Post-infectious acute glomerulonephritis with predominant mesangial lgA. Clin Exp Nephrol (2005) 9(3): 263.

Lau KL, Gaber L W, Delos Santos NM, and Wyatt RJ. Clq nephropathy: features at presentation and outcome. Pediatr Nephrol (2005) 20(6): 744-749.

Lau KL, Gaber LW, Delos Santos NM, Fisher KA, Grimes SJ, and Wyatt RJ. Pediatric IgA nephropathy: Similar clinical features at presentation and outcome for African-Americans and Caucasians. Clinical Nephrology (2004) 62 (3): 167-172.

Delos Santos NM and Wyatt RJ. Pediatric lgA nephropathies: Clinical aspects and therapeutic approaches. Seminars in Nephrology (2004) May; 24 (3): 269-286.

Gardner LA, Delos Santos NM, Matta SG, Whitt MA, and Bahouth SW. Role of the cyclic AMP-dependent protein kinase in homologous resensitization of the betal-adrenergic receptor. Journal of Biological Chemistry (2004) May; 279 (20): 21135-43.

Delos Santos NM, Ault BH, Gharavi AG, Kritchevsky SB, Quasney MW, Jackson EC, Fisher KA, Woodford SY, Mitchell BM, Gaber LW, and Wyatt RJ. Angiotensin-converting enzyme genotype and prognosis in pediatric IgA nephropathy. Pediatric Nephrology (2002) July; 17 (7): 496-502.

Last update: March 2018