Katherine M. Knapp, MD

Katherine M. Knapp, MD

  • Staff Physician



BA – Vanderbilt University, Nashville, Tennessee (1990)
MD – University of Arkansas for Medical Sciences, Little Rock, Arkansas (1994)

Research Interests

  • Pediatric and adolescent HIV/AIDS, particularly prevention of mother-to-child transmission
  • Infectious complications in immunocompromised hosts, particularly fungal infections

Selected Publications

Steinbach WJ, Roilides E, Berman D, Hoffman JA, Groll AH, Bin-Hussain I, Palazzi DL, Castagnola E, Halasa N, Velegraki A, Dvorak CC, Charkabarti A, Sung L, Danziger-Isakov L, Lachenauer C, Arrieta A, Knapp K, Abzug MJ, Ziebold C, Lehrnbecher T, Klingspor L, Warris A, Leckerman K, Martling T, Walsh TJ, Benjamin DK Jr, Zaoutis TE, International Pediatric Fungal Network. Results from a prospective, international, epidemiologic study of invasive candidiasis in children and neonates.Pediatr Infect Dis J Sept 13, 2012.

Knapp KM, Read JS. Efavirenz is not a known teratogen. Pediatr Infect Dis J May 18, 2012.

Knapp K, Brogly SB, Muenz DG, Spiegel HM, Conway DH, Scott GB, Talbot JT, Shapiro DE, Read JS, for the P1025 Team of the International Maternal Pediatric Adolescent AIDS Clinical Trials Group. Prevalence of congenital anomalies in infants with in utero exposure to antiretrovirals. Pediatr Infect Dis J 31(2):164-70, 2011.

Kontoyiannis DP, Marr KA, Park BJ, Alexander BD, Anaissie EJ, Walsh TJ, Ito J, Andes DR, Baddley JW, Brown JM, Brumble LM, Freifeld AG, Hadley S, Herwaldt LA, Kauffman CA, Knapp K, Lyon GM, Morrison VA, Papanicolaou G, Patterson TF, Perl TM, Schuster MG, Walker R, Wannemuehler KA, Wingard JR, Chiller TM, Pappas PG. Prospective Surveillance for Invasive Fungal Infections in Hematopoietic Stem Cell Transplant Recipients, 2001-2006: Overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database. Clin Infect Dis Apr 50(8):1091-100, 2010.

Hakim H, Flynn PM, Srivastava DK, Knapp KM, Li C, Okuma J, Gaur AH. Risk Prediction in Pediatric Cancer Patients with Fever and Neutropenia. Pediatr Infect Dis J Jan;29(1):53-59, 2010.

Minniear TD, Gilmore B, Arnold SR, Flynn PM, Knapp KM, Gaur AH. Implementation of and Barriers to Routine HIV Screening for Adolescents. Pediatrics Oct;124(4):1076-1084, 2009.

Hakim H, Flynn PM, Knapp KM, Srivastava DK, Gaur AH. Etiology and Clinical Course of Febrile Neutropenia in Children with Cancer. J Pediatr Hematol Oncol Sep; 31(9):623-629, 2009.

Neely M, Jafri HS, Seibel N, Knapp K, Adamson PC, Bradshaw SK, Strohmaier KM, Sun P, Bi S, Dockendorf MF, Stone JA, and Kartsonis NA. The Pharmacokinetics and Safety of Caspofungin in Older Infants and Toddlers. Antimicrob Agents Chemother Apr; 53(4):1450-1456, 2009.

Hayden R, Pounds S, Knapp K, Petraitiene R, Schaufele RL, Sein T, Walsh TJ. Galactomannan Antigenemia in Pediatric Oncology Patients with Invasive Aspergillosis. Pediatr Infect Dis J Sep; 27(9):815-819, 2008.

Burgos A, Zaoutis T, Dvorak C, Hoffman J, Knapp KM, Nania J, Prasad, Steinbach WJ. Pediatric Invasive Aspergillosis: A Multicenter Retrospective Analysis of 139 Contemporary Cases. PediatricsMay; 121(5):e1286-e1294, 2008.

Flynn PM, Rodman J, Lindsey JC, Robbins B, Capparelli E, Knapp KM, Rodriguez JF, McNamara J, Serchuck L, Heckman B, Martinez J; the PACTG 1012 Team. Intracellular Pharmacokinetics of Once versus Twice Daily Zidovudine and Lamivudine in Adolescents. Antimicrob Agents Chemother Oct; 51(10):3516-3522, 2007.

Barfield RC,Hale GA, Burnette K, Behm FG, Knapp K, Eldridge P, and Handgretinger R. Autologous transplantation of CD133 selected hematopoietic progenitor cells for treatment of relapsed acute lymphoblastic leukemia. Pediatr Blood Cancer March; 48(3):349-353, 2007.

Buckingham SC, McCullers JA, Lujan-Zilbermann J, Knapp KM, Orman KL, and English BK. Early vancomycin therapy and adverse outcomes in children with pneumococcal meningitis. Pediatrics May; 117(5):1688-1694, 2006.

Hardin AO, Meals EA, Yi T, Knapp KM, and English BK. SHP-1 inhibits LPS-mediated TNF and iNOS production in murine macrophages. Biochem Biophys Res Commun Apr 7;342(2):547-555, 2006.

Knapp KM, Flynn PM. Newer Treatments for Fungal Infections. J Support Oncol July/August; 3(4):290-298, 2005.

Gaur AH, Liu T, Knapp KM, Daw NC, Rao BN, Neel MD, Rodriguez-Galindo C, Brand D, and Adderson EE. Infections in patients with bone malignancies undergoing limb-sparing surgery. CancerJun; 104(3):602-610, 2005.

El Saleeby CM, Allison KJ, Knapp KM, Walsh TJ, Hayden RT. Discordant rise in galactomannan antigenemia in a patient with resolving aspergillosis and renal failure. J Clin Microbiol Jul; 43(7):3560-3563, 2005.

Miyairi I, Franklin JA, Andreansky M, Knapp KM, Hayden RT. Acute necrotizing ulcerative gingivitis and bacteremia caused by Stenotrophomonas maltophilia in an immunocompromised host. Pediatr Infect Dis J Feb; 24(2):181-183, 2005.

McCarty ML, Wilson MW, Fleming JC, Thompson JW, Sandlund JT, Flynn PM, Knapp KM, Haik BG, Ribeiro RC. Manifestations of fungal cellulitis of the orbit in children with neutropenia and fever.Ophthal Plast Reconstr Surg May; 20(3):217-223, 2004.

Godambe SA, Knapp KM, Meals EA, English BK. Role of vav1 in the lipopolysaccharide-mediated upregulation of inducible nitric oxide synthase production and nuclear factor for interleukin-6 expression activity in murine macrophages. Clin Diagn Lab Immunol May; 11(3):525-531, 2004.

Lujan-Zilbermann J, Bitar W, Knapp K, Flynn P. Human immunodeficiency virus type 1 RNA polymerase chain reaction reasonably excludes infection in exposed infants. Pediatr Infect Dis J Jan; 22(1):97-98, 2003.

Buckingham SC, Crouse DT, Knapp KM, Patrick CC. Pneumonitis associated with Ureaplasma urealyticum in children with cancer. Clin Infect Dis Jan; 36:225-228, 2003.

Buckingham SC, McCullers JA, Lujan-Zilbermann J, Knapp KM, Orman KL, English BK. Pneumococcal meningitis in children: relationship of antibiotic resistance to clinical characteristics and outcomes. Pediatr Infect Dis J Sept; 20:837-843, 2001.

Knapp KM, English BK. Ceramide-mediated stimulation of inducible nitric oxide synthase (iNOS) and tumor necrosis factor (TNF) accumulation in murine macrophages requires tyrosine kinase activity. J Leukoc Biol May; 67:735-741, 2000.

Last update: September 2012