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Ulrike M. Reiss, MD
Ulrike M. Reiss, MD

Ulrike M. Reiss, MD

Associate Member, St. Jude Faculty

  • Director, Hemophilia Treatment Center

Departments

Divisions

Education

MD – University of Heidelberg, Germany (1989)
Residency (Pediatrics) – University of Heidelberg and University of Ulm, Germany; State University of New York at Stony Brook, NY and Children's Hospital Oakland, CA
Fellowship (Pediatric Hematology/Oncology) – Children's Hospital Oakland, CA

Research Interests

  • Bleeding disorders
  • Thrombosis
  • Bone marrow failure syndromes

Selected Publications

Bhoopalan SV, Wlodarski M, Reiss U, Triplett B, Sharma A. Reduced-intensity conditioning-based hematopoietic cell transplantation for dyskeratosis congenita: Single-center experience and literature review. Pediatr Blood Cancer Oct;68(10):e29177, 2021. doi: 10.1002/pbc.29177. Epub 2021 Jun 4. PMID: 34086408

Bolous NA, Chen Y, Davidoff A, Devidas M, Jacobs T, Meagher M, Piras B, Reiss UM, Bhakta N. Cost-effectiveness of three different treatment approaches for severe hemophilia B. Blood Apr, 2021. doi: 10.1182/blood.2021010864. Epub Apr 25. PMID: 33895800

Lesmana H, Jacobs T, Boals M, Gray N, Lewis S, Ding J, Kang G, Hale M, Weiss M, Reiss U, Wang W, Wlodarski M. Eltrombopag in children with severe aplastic anemia. Pediatr Blood Cancer Aug;68(8):e29066, 2021. doi: 10.1002/pbc.29066. Epub 2021 Apr 15. PMID: 33855784

McEneny-King A, Chelle P, Goggans MH, Barker PJ, Jacobs, TW, Neufeld EJ, Reiss UM, Panetta JC. Limited sampling strategies for accurate determination of extended half-life factor VIII pharmacokinetics in severe hemophilia A patients. Haemophilia  27(3):408-416, 2021. doi: 10.1111/hae.14288. Epub 2021 Mar 20. PMID: 33742733

Shapiro AD, Ragni M, Borhany M, Abajas Y, Tarantino M, Holstein K, Croteau SE, Liesner R, Tarango C, Carvalho M, McGuinn C, Funding E2, Kempton CL, Bidlingmaier C, Cohen A, Oldenburg J, Kearney S, Knoll C, Kuriakose P, Acharya S, Reiss UM, Kulkarni R, Shullick M, Lethagen S, Donfield S, LeBeau P, Berntorp E, Astermark J. Natural history study of factor IX deficiency with focus on treatment and complications (B-Natural). Haemophilia 27(1):49-59, 2021. doi: 10.1111/hae.14139. Epub 2020 Dec 5. PMID: 33278853 

Mesleh Shayeb A, Li C, Kang G, Reiss UM, Elbahlawan L. Use of recombinant activated factor VII for uncontrolled bleeding in a hematology/oncology paediatric ICU cohort. Blood Coagul Fibrinolysis 31(7):440-444, 2020. PMID: 32833802

Mesleh Shayeb A, Su Y, Kang G, Elbahlawan L, Reiss UM. Efficacy and safety of recombinant activated factor VII off-label use in a pediatric hematology/oncology cohort. J Pediatr Hematol Oncol 41(2):e72-e78, 2019. PMID: 30608491

Saini A, West AN, Harrell C, Jones TL, Nellis ME, Joshi AD, Cowan KM, Gatewood CW, Ryder AB, Reiss UM. Platelet transfusions in the PICU: does disease severity matter? Pediatr Crit Care Med 19(9):e472-e478, 2018. PMID: 29927877

Estepp JH, Smeltzer MP, Kang G, Howard S, Reiss U. Safe use of low molecular weight heparin in pediatric acute lymphoblastic leukemia and lymphoma around lumbar punctures. J Pediatr Hematol Oncol 39(8):596-601, 2017. PMID: 28991227

Nathwani AC, Reiss UM, Tuddenham EG, Rosales C, Chowdary P, McIntosh J, Peruta MD, Lheriteau E, Patel N, Raj D, Riddell A, Pie J, Rangarajan S, Bevan D, Recht M, Shen YM, Halka KG, Basner-Tschakarjan E, Mingozzi, F, High, KA, Allay J, Kay MA, Ng CY, Zhou J, Cancio M, Morton CL, Gray JT, Srivastava D, Nienhuis AW, Davidoff AM. Long term safety and efficacy of human FIX gene therapy in hemophilia B. N Engl J Med 371(21):1994-2004, 2014. PMID: 25409372

Reiss UM, Schwartz J, Sakamoto KM, Puthenveetil G, Ogawa M, Bedrosian CL, Ware RE. Efficacy and safety of eculizumab in children and adolescents with paroxysmal nocturnal hemoglobinuria. Pediatr Blood Cancer 61:1544-1550, 2014. PMID 24777716

Hoffman JM, Haidar CE, Wilkinson MR, Crews KR, Baker DK, Kornegay NM, Yang W, Pui CH, Reiss UM, Gaur AH, Howard SC, Evans WE, Broeckel U, Relling MV.  PG4KDS: A model for the clinical implementation of pre-emptive pharmacogenetics.  Am J Med Genet C Semin Med Genet 166:45-55, 2014. PMID 24619595, PMCID: PMC4056586

Williams DA, Bennett C, Bertuch A, Bessler M, Coates T, Corey S, Dror Y, Huang J, Lipton J, Olson TS, Reiss UM, Rogers ZR, Sieff C, Vlachos A, Walkovich K, Wang W, Shimamura A, on behalf of the North American Pediatric Aplastic Anemia Consortium.  Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): an initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC).  Pediatr Blood Cancer 61:869-874, 2014. PMID:24285674, PMCID: PMC4280184

Berntorp E, Shapiro AD, Waters J, Astermark J; International Factor IX Treatment Network. The international factor IX treatment network survey. Haemophilia 18:e60-62, 2012. PMID: 22404549

Hay CR, DiMichele DM; International Immune Tolerance Study Group. The principal results of the International Immune Tolerance Study: a randomized dose comparison. Blood 9:1335-1344, 2012. PMID: 22101900

Nathwani AC, Tuddenham EG, Rangarajan S, Rosales C, McIntosh J, Linch DC, Chowdary P, Riddell A, Pie AJ, Harrington C, O’Beirne J, Smith K, Pasi J, Glader B, Rustagi P, Ng CY, Kay MA, Zhou J, Spence Y, Morton CL, Allay J, Coleman J, Sleep S, Cunningham JM, Srivastava D, Basner-Tschakarjan E, Mingozzi F, High KA, Gray JT, Reiss UM, Nienhuis AW, Davidoff AM. Adenovirus-associated virus vector-mediated gene transfer in hemophilia B. N Engl J Med 365:2357-2365, 2011. PMID22149959, PMCID: 3265081

Du H-Y, Pumbo E, An P, Bagby G, Maziarz RT, Reiss UM, Chirnomas D, Shimamura A, Vlachos A, Lipton J, Goyal RK, Goldman F, Wilson DB, Mason PJ, Bessler M.  TERC and TERT gene mutations in patients with bone marrow failure and the significance of telomere length measurements. Blood 113:309-316, 2009. PMID: 18931339

Reiss UM, Bensimhon P, Zimmerman SA, Ware RE. Hydroxyurea therapy for management of secondary erythrocytosis in cyanotic congenital heart disease. Am J Hematol 82:740-743, 2007. PMID: 17506064

Reiss U, Oskouian B, Zhou J, Gupta V, Sooriyakumaran P, Kelly S, Wang E, Merrill AH, Saba JD. Sphingosine phosphate lyase enhances stress-induced ceramide generation and apoptosis. J Biol Chem 279:1281-1290, 2004. PMID: 14570870

Last update: September 2021