Lindsay J. Talbot, MD
Lindsay J. Talbot, MD

Lindsay J. Talbot, MD

Instructor, St. Jude Faculty

Departments

Education

BA, BA, BS – North Carolina State University, Raleigh, North Carolina
MD – Duke University School of Medicine, Durham, North Carolina
General Surgery Residency – Duke University, Durham, North Carolina
Surgical Critical Care Fellowship – Comer Children’s Hospital, Chicago, Illinois
Pediatric Surgery Fellowship Fellowship – Nationwide Children’s Hospital, Columbus, Ohio

Research Interests

  • Immunologic profiles of sarcoma primary and metastatic sites
  • Immunotherapy strategies, including CAR T-cell therapy, against osteosarcoma and other solid tumors
  • Role of chemokine-mediated homing of CAR T-cells in improving treatment efficacy in osteosarcoma and solid tumors

Selected Publications

Gulack BC, Rialon KL, Englum BR, Kim J, Talbot LJ, et al. Factors associated with survival in pediatric adrenocortical carcinoma: An analysis of the National Cancer Data Base (NCDB). J Pediatr Surg Jan;51(1):172-7, 2016. PubMed PMID: 26572849

Gulack BC, Englum BR, Rialon KL, Talbot LJ, Keenan JE, et al. Inequalities in the use of helmets by race and payer status among pediatric cyclists. Surgery Aug;158(2):556-61, 2015. PubMed PMID: 26044110

Weber CE, Talbot LJ, Geller JM, Kuo MC, Wai PY, et al. Obesity and trends in malpractice claims for physicians and surgeons. Surgery Aug;154(2):299-304, 2013. PubMed PMID: 23777584.

Weber CE, Talbot LJ, Geller JM, Kuo MC, Wai PY, et al. Comparing 20 years of national general surgery malpractice claims data: obesity versus morbid obesity. Am J Surg Mar;205(3):293-7; discussion 297, 2013. PubMed PMID: 23332690

Wai PY, O'Hern T, Andersen DO, Kuo MC, Weber CE, Talbot LJ, et al. Impact of business infrastructure on financial metrics in departments of surgery. Surgery Oct;152(4):729-34; discussion 734-7, 2012. PubMed PMID: 23021138

Bhattacharya SD, Mi Z, Talbot LJ, Guo H, Kuo PC. Human mesenchymal stem cell and epithelial hepatic carcinoma cell lines in admixture: concurrent stimulation of cancer-associated fibroblasts and epithelial-to-mesenchymal transition markers. Surgery Sep;152(3):449-54, 2012. PubMed PMID: 22938903; NIHMSID: NIHMS399487; PubMed Central PMCID: PMC3432987

Crose LE, Etheridge KT, Chen C, Belyea B, Talbot LJ, et al. FGFR4 blockade exerts distinct antitumorigenic effects in human embryonal versus alveolar rhabdomyosarcoma. Clin Cancer Res Jul 15;18(14):3780-90, 2012. PubMed PMID: 22648271; NIHMSID: NIHMS452195; PubMed Central PMCID: PMC3713717

Bhattacharya SD, Mi Z, Kim VM, Guo H, Talbot LJ, et al. Osteopontin regulates epithelial mesenchymal transition-associated growth of hepatocellular cancer in a mouse xenograft model. Ann Surg Feb;255(2):319-25, 2012. PubMed PMID: 22241292; NIHMSID: NIHMS340032; PubMed Central PMCID: PMC3725267

Talbot LJ, Bhattacharya SD, Kuo PC. Epithelial-mesenchymal transition, the tumor microenvironment, and metastatic behavior of epithelial malignancies. Int J Biochem Mol Biol 3(2):117-36, 2012. PubMed PMID: 22773954; PubMed Central PMCID: PMC3388731

Talbot LJ, Mi Z, Bhattacharya SD, Kim V, Guo H, et al. Pharmacokinetic characterization of an RNA aptamer against osteopontin and demonstration of in vivo efficacy in reversing growth of human breast cancer cells. Surgery Aug;150(2):224-30, 2011. PubMed PMID: 21801960; NIHMSID: NIHMS299493; PubMed Central PMCID: PMC3148491

Mi Z, Bhattacharya SD, Kim VM, Guo H, Talbot LJ, et al. Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis. Carcinogenesis Apr;32(4):477-87, 2011. PubMed PMID: 21252118; PubMed Central PMCID: PMC3105582

Tracy ET, Talbot LJ, Kurtzberg J, Rice HE. Splenectomy and partial splenectomy improve hematopoietic stem cell engraftment in hypersplenic mice. J Pediatr Surg Jun;45(6):1365-9, 2010. PubMed PMID: 20620346

Jones LD, Payne ME, Messer DF, Beyer JL, MacFall JR, et al. Temporal lobe volume in bipolar disorder: relationship with diagnosis and antipsychotic medication use. J Affect Disord Apr;114(1-3):50-7, 2009. PubMed PMID: 18691766; NIHMSID: NIHMS74623; PubMed Central PMCID: PMC2643314

Last update: August 2018