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Selene Koo, MD, PhD
Selene Koo, MD, PhD

Selene Koo, MD, PhD

Assistant Member, St. Jude Faculty



Postdoctoral Fellowship (Pediatric Pathology) - Boston Children’s Hospital, Boston, MA
Postdoctoral Fellowship (Molecular Genetic Pathology) - University of Chicago Medicine, Chicago, IL
Residency (Anatomic and Clinical Pathology) - University of Chicago Medicine, Chicago, IL
MD - University of Chicago Pritzker School of Medicine, Chicago, IL
PhD - University of Chicago, Chicago, IL
BA, BS - University of California Berkeley, Berkeley, CA

Research Interests

  • Diagnosis and classification of pediatric solid tumors
  • Histologic and molecular characterization of pediatric solid tumors

Selected Publications

Gupta A, Belsky JA, Schieffer KM, Leraas K, Varga E, McGrath SD, Koo SC, Magrini V, Wilson RK, White P, Mardis ER, Jatana KR, Cottrell CE, Setty BA. Infantile fibrosarcoma-like tumor driven by novel RBPMS-MET fusion consolidated with cabozantinib. Cold Spring Harbor Molecular Case Studies 6(5):a005645, 2020. doi: 10.1101/mcs.a005645.

Avenarius MR, Miller CR, Arnold MA, Koo S, Roberts R, Hobby M, Grossman T, Moyer Y, Wilson RK, Mardis ER, Gastier-Foster JM, Pfau R. Genetic characterization of pediatric sarcomas by targeted RNA sequencing. Journal of Molecular Diagnostics 22(10):1238-1245, 2020.

Orr A, Liu H, Mariani R, Aldrink JH, Setty BA, Koo S. Bilateral lung metastases from a phalangeal giant cell tumor of bone. Pediatric and Developmental Pathology 24(1):51-55, 2020. doi:10.1177/1093526620964351.

Koo SC, Bu F. Intraplacental leiomyoma in a case of second-trimester intrauterine fetal demise. Clinical Pathology 13:2632010X20928328, 2020.

Koo SC, Janeway KA, Harris MH, Fryer CJ, Aster JC, Al-Ibraheemi A, Church AJ. A distinctive genomic and immunohistochemical profile for NOTCH3 and PDGFRB in myofibroma with diagnostic and therapeutic implications. International Journal of Surgical Pathology 28(2):128-137, 2020.

Lu J, Koo SC, Weissman BP, Harris ME, Li NS, Piccirilli JA. Evidence that nucleophile deprotonation exceeds bond formation in the HDV ribozyme transition state. Biochemistry 57(25):3465-3472, 2018.

Koo SC, Lu J, Li NS, Leung E, Das SR, Harris ME, Piccirilli JA. Transition state features in the hepatitis delta virus ribozyme reaction revealed by atomic perturbations. Journal of the American Chemical Society 137(28):8973-8982, 2015.

Lu J, Koo SC, Li NS, Piccirilli JA. Synthesis of 2’-O-photocaged ribonucleoside phosphoramidites. Nucleosides Nucleotides and Nucleic Acids 34:114-129, 2015.

Li NS, Frederiksen JK, Koo SC, Lu J, Wilson TJ, Lilley DMJ, Piccirilli JA. A general and efficient approach for the construction of RNA oligonucleotides containing a 5’-phosphorothiolate linkage. Nucleic Acids Research 39:e31, 2011.

Last update: April 2021