MD – University of Alabama at Birmingham
- Influenza viruses
- Viral-bacterial synergism
Hakim H, Allison KJ, Van De Velde LA, Li Y, Flynn P, McCullers JA. Immunogenicity and safety of inactivated monovalent 2009 H1N1 influenza A vaccine in immunocompromised children and young adults. Vaccine December 8, 2011.
Alymova IV, Green AM, van de Velde N, McAuley JL, Boyd KL, Ghoneim H, McCullers JA. Immunopathogenic and anti-bacterial effects of the H3N2 influenza A virus PB1-F2 map to amino acid residues 62, 75, 79, and 82. J Virol September 21, 2011.
Karlström Å, Heston SM, Boyd KL, Tuomanen EI, McCullers JA. Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary bacterial pneumonia following influenza. J Infect Dis September 7, 2011.
Weeks JN, Boyd KL, Gowrisankar R, Ades EW, McCullers JA. Combined immunotherapy with intravenous immune globulin and P4 peptide rescues mice from post-influenza pneumococcal pneumonia. Antimicrob Agents Chemother 555(5), 2011.
Iverson AR, Boyd KL, McAuley JL, Plano LR, Hart ME, McCullers JA. Influenza virus primes mice for pneumonia from Staphylococcus aureus. J Infect Dis January 28, 2011.
Reichert TA, Gerardo C, Nishiura H, McCullers JA. Does Glycosylation as a modifier of Original Antigenic Sin explain the case age distribution and unusual toxicity in pandemic novel H1N1 influenza?BMC Infectious Diseases, 10(5), 2010.
Huber VC, Peltola V, McCullers JA. Contribution of vaccine-induced immunity toward either the HA or the NA component of influenza viruses toward limiting secondary bacterial complications. J Virol 84(8), 4105-8, 2010.
McAuley JL, Zhang K, McCullers JA. The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesis. J Virol 84(1):558-64, 2010.
Wanzeck K, Boyd KL, McCullers JA. Glycan shielding of the influenza virus hemagglutinin contributes to immunopathology in mice. Am J Respir Crit Care Med October 8, 2010.
McCullers JA, Van De Velde LA, Schultz RD, Mitchell CG, Halford CR, Boyd KL, Schultz-Cherry S. Seroprevalence of seasonal and pandemic influenza A viruses in domestic cats. Arch Virol September 28, 2010.
McCullers JA, McAuley JL, Browall S, Iverson AR, Boyd KL, Henriques Normark B. Influenza enhances susceptibility to natural acquisition of and disease due to Streptococcus pneumoniae in ferrets. J Infect Dis September 7, 2010.
McAuley JL, Chipuk JE, Boyd KL, Van De Velde N, Green DR, McCullers JA. PB1-F2 proteins from H5N1 and 20th century pandemic influenza viruses cause immunopathology. PLoS Pathog 6(7) e1001014m, 2010.
Karlström Å, Boyd KL, English BK, McCullers JA. Treatment with protein synthesis inhibitors improves outcomes from secondary bacterial pneumonia following influenza. J Inf Dis 199(3), 311-9, 2009.
Huber VC, Thomas PG, McCullers JA. A Multi-valent Vaccine Approach That Elicits Broad Immunity Within an Influenza Subtype. Vaccine 27:1192-1200, 2009.
McCullers JA, English BK. Improving therapeutic strategies for secondary bacterial pneumonia following influenza. Fut Microb 3(4):397-404, 2008.
Huber VC, McCullers JA. Vaccines against pandemic influenza; what can be done before the next pandemic? Ped Inf Dis J 27:S113-7, 2008.
Huber VC, Kleimeyer LH, McCullers JA. Live, attenuated influenza virus (LAIV) vehicles are strong inducers of immunity toward influenza B virus. Vaccine 26(42):5381-8, 2008.
McAuley J, Horning F, Boyd KL, Smith AM, McKeon R, Bennink J, Yewdell J, McCullers JA. The 1918 PB1-F2 protein contributes to virulence and immunopathology of primary viral and secondary bacterial infections. Cell Host Microbe 2:240-9, 2007.
McCullers JA, Karlstrom A, Iverson AR, Loeffler J, Fischetti VA. A novel strategy to prevent otitis media caused by colonizing Streptococcus pneumoniae. PLOS Pathogens 3(3):e28, 2007.
Vigerust DJ, Ulett KB, Madsen J, Hawgood S, McCullers JA. N-linked glycosylation attenuates H3N2 influenza viruses. J Virol 81(16):8593-600, 2007.
Huber VC, McCullers JA. Live Attenuated Influenza Vaccine is Safe and Immunogenic in Immunocompromised Ferrets. J Infect Dis 193(5):677-84, 2006.
Huber VC, McKeon RM, Brackin MN, Miller LA, Keating R, Brown SA, Makarova NI, Perez DR, MacDonald G, McCullers JA. Distinct roles for IgG1 and IgG2a antibodies in the development of DNA and viral replicon particle-based influenza vaccines. Clin Vacc Immunol 13(9):981-90, 2006.
Peltola VT, Boyd KL, McAuley JL, Rehg J, McCullers JA. Bacterial sinusitis and otitis media in ferrets following influenza. Infect Immun 74(5):2562-7, 2006.
McCullers JA. Insights into the interaction between influenza virus and pneumococcus. Clin Micro Rev 19(3):571-82, 2006.
Last update: December 2011