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Charles G. Mullighan, MBBS (Hons), MSc, MD

Member, St. Jude Faculty

Co-Leader, Hematological Malignancies Program

Medical Director, St. Jude Biorepository

William E. Evans Endowed Chair

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Contact Information

Charles G. Mullighan, MBBS (Hons), MSc, MD

Pathology

MS 342, Room D4047D

St. Jude Children's Research Hospital

262 Danny Thomas Place

MemphisTN 38105-3678

Quick Facts

Mullighan was named a Fellow of the elite Royal Society of London for his trailblazing contributions to genome research in ALL.

Education

MBBS (Hons) – University of Adelaide, Australia (1993) MSc – University of London, England (1997) MD – University of Adelaide, Australia (1998) Fellowship – Royal College of Pathologists of Australasia (2004) Fellowship – Royal Australasian College of Physicians (2004)

Honors & Awards

  • 2017 National Cancer Institute R35 Outstanding Investigator Award
  • 2016  American Society of Hematology William Dameshek Prize
  • 2016 St. Baldrick's Foundation Robert J. Arceci Innovation Award inaugural recipient
  • 2016 Elected member, American Association of Physicians
  • 2015 Fellow, Australian Academy of Health and Medical Sciences
  • 2015 United States and Canadian Academy of Pathology Ramzi Cotran Young Investigator Award
  • 2012 Meyenburg Award for Cancer Research
  • 2012 Elected member, American Society of Clinical Investigation
  • 2009 Pew Scholar in the Biomedical Sciences
  • 2009 American Association for Cancer Research Team Science Award (with the St. Jude Children’s Research Hospital Hematologic Malignancies Program)
  • 2009 Society for Pediatric Pathology Lotte Strauss Prize
  • 2008 American Society of Hematology Joanne Levy, MD, Memorial Award for Outstanding Achievement
  • 2007 American Society of Hematology Scholar Award
  • 2007 American Society of Hematology Merit Award

Research Interests

  • The use of integrated genomic and epigenomic approaches to understand the pathogenesis and evolution of acute lymphoblastic leukemia (ALL) and related disorders
  • Defining the interaction of inherited and somatic genetic alterations in leukemogenesis
  • The use of in vitro and in vivo experimental approaches to model genomic abnormalities in leukemogenesis
  • Preclinical therapeutic testing to translate genomic discoveries to new treatment approaches in ALL

Clinical Trials

Recruiting
TBANK: Collecting, Banking, and Distributing Human Tissue Samples in St. Jude Biorepository

Study goal:

To provide a high-quality repository of tumor and normal samples to facilitate translational research performed by St Jude faculty and their collaborators

Dr. Mullighan in Progress

Dr. Mullighan in St. Jude News