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Harshan Pisharath, DVM, PhD, DACLAM
Harshan Pisharath, DVM, PhD

Harshan Pisharath, DVM, PhD

Associate Member, St. Jude Faculty

  • Director, Animal Resources Center



PhD - The Johns Hopkins University School of Medicine, Baltimore, MD
Postdoctoral Fellowship (Comparative Medicine & Pathology) - The Johns Hopkins University School of Medicine, Baltimore, MD 
Bachelor of Veterinary Science & Animal Husbandry - College of Veterinary & Animal Sciences, Mannuthy, Kerala, India

Research Interests

  • Animal models of human diseases
  • Preclinical safety assessment

Selected Publications

Mirsky ML, Portugal S, Pisharath H, Osowski JL, Kearney L. Utility of Orchidometric Parameters for Assessing Sexual Maturation in Male Cynomolgus Macaques (Macaca fascicularis). Comp Med Dec 1;66(6):480- 48, 2016.

Carvallo FR, Kerlin R, Fredette C, Pisharath H, DebRoy C, Kariyawasam S, Pardo ID. Histiocytic typhlocolitis in two colony Beagle dogs. Exp Toxicol Pathol Feb;67(2):219-21, 2015.

Harshan Pisharath, Chih-Ling Zao, John Kreeger, Susan Portugal, Thomas Kawabe, Tarea Burton, Lisa Tomaeck, Ahmed Shoieb, Brandy Morenko Campbell, Judy Franco. Immunopathological characterization of naturally acquired Trypanosoma cruzi infection and cardiac sequalae in cynomolgus macaques (Macaca fascicularis).  J Am Assoc Lab Anim Sci Sep;52(5):545-52, 2013.

Parsons MJ, Pisharath H, Yusuff S, Moore JC, Siekmann AF, Lawson N, Leach SD. Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas.  Mech Dev Oct;126(10):898-912, 2009.

Pisharath H, Parsons MJ. Nitroreductase mediated cell ablation in transgenic zebrafish. Methods Mol Biol 546:133-43, 2009.

Pisharath H. Validation of nitroreductase, a prodrug- activating enzyme, mediated cell death in embryonic zebrafish (Danio rerio). Comp Med Jun;3:241-244, 2007.

Pisharath H, Rhee JM, Swanson MA, Leach SD, Parsons MJ. Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase. Mech Dev Mar;124(3):218-29, 2007.

Pisharath HR, Cooper TK, Brice AK, Cianciolo RE, Pistorio AL, Wachtman LM, Mankowski JL, Newcomer CE. Septicemia and peritonitis in a colony of common marmosets (Callithrix jacchus) secondary to Klebsiella pneumoniae infection. Contemp Top Lab Anim Sci Jan;44(1):35-37, 2005.

Last update: February 2019