Ulrike M. Reiss, MD
Ulrike M. Reiss, MD

Ulrike M. Reiss, MD

Associate Member, St. Jude Faculty

  • Director, Clinical Hematology Division
  • Director, Hemophilia Treatment Center




MD – University of Heidelberg, Germany (1989)
Residency (Pediatrics) – University of Heidelberg and University of Ulm, Germany; State University of New York at Stony Brook, NY and Children's Hospital Oakland, CA
Fellowship (Pediatric Hematology/Oncology) – Children's Hospital Oakland, CA

Research Interests

  • Bleeding disorders
  • Thrombosis
  • Bone marrow failure syndromes

Selected Publications

Berntorp E, Shapiro AD, Waters J, Astermark J; International Factor IX Treatment Network. The international factor IX treatment network survey. Haemophilia 18:e60-62, 2012.

Estepp JM, Smeltzer M, Reiss UM. The impact of quality and duration of enoxaparin therapy on recurrent venous thrombosis in children. Pediatr Blood Cancer 59:105-109, 2012.

Hay CR, DiMichele DM; International Immune Tolerance Study Group. The principal results of the International Immune Tolerance Study: a randomized dose comparison. Blood 9:1335-44, 2012.

Baskin JL, Reiss U, Wilimas JA, Metzger ML, Ribeiro RC, Pui CH, Howard SC. Thrombolytic therapy for central venous catheter occlusion. Haematologica 97:641-650, 2012.

Nathwani AC, Tuddenham EG, Rangarajan S, Rosales C, McIntosh J, Linch DC, Chowdary P, Riddell A, Pie AJ, Harrington C, O’Beirne J, Smith K, Pasi J, Glader B, Rustagi P, Ng CY, Kay MA, Zhou J, Spence Y, Morton CL, Allay J, Coleman J, Sleep S, Cunningham JM, Srivastava D, Basner-Tschakarjan E, Mingozzi F, High KA, Gray JT, Reiss UM, Nienhuis AW, Davidoff AM. Adenovirus-associated virus vector-mediated gene transfer in hemophilia B. N Engl J Med 365:2357-65, 2011.

Morris VK, Spraker HL, Howard SC, Ware RE, Reiss UM. Severe thrombocytopenia with iron deficiency anemia. Pediatr Hematol Oncol 27:413-419, 2010.

Leary SE, Harrod VL, de Alarcon PA, Reiss UM. Efficacy and safety of low dose systemic thrombolytic therapy for deep vein thrombosis in pediatric patients. J Pediatr Hematol Oncol 32:97-102, 2010.

Reiss UM. 50 Years Ago in The Journal of Pediatrics "Ristocetin, a laboratory and clinical evaluation in children" Koch R. J Pediatr 1960;56:498-504. J Pediatr 156:531, 2010.

Kulkarni R, Soucie JM, Lusher J, Presley R, Shapiro A, Gill J, Manco-Johnson M, Koerper M, Mathew P, Abshire T, Dimichele D, Hoots K, Janco R, Nugent D, Geraghty S, Evatt B; Haemophilia Treatment Center Network Investigators. Sites of initial bleeding episodes, mode of delivery and age of diagnosis in babies with haemophilia diagnosed before the age of 2 years: a report from The Centers for Disease Control and Prevention's (CDC) Universal Data Collection (UDC) project. Haemophilia 15:1281-1290, 2009.

Metjian AD, Wang C, Sood SL, Cuker A, Peterson SM, Soucie JM, Konkle BA, the HTCN Study Investigators. Bleeding symptoms and laboratory correlation in patients with severe von Willebrand disease. Haemophilia 15(4):918-925, 2009.

Maurer SH, Wilimas JA, Wang WC, Reiss UM. Heparin induced thrombocytopenia and re-thrombosis associated with warfarin and fondaparinux in a child. Pediatr Blood Cancer 53:468-471, 2009.

Du H-Y, Pumbo E, An P, Bagby G, Maziarz RT, Reiss UM, Chirnomas D, Shimamura A, Vlachos A, Lipton J, Goyal RK, Goldman F, Wilson DB, Mason PJ, Bessler M. TERC and TERT gene mutations in patients with bone marrow failure and the significance of telomere length measurements. Blood 113:309-316, 2009.

Morris EB, Kasow K, Reiss U, Ellison D, Broniscer A. Bone marrow transplantation for severe aplastic anemia secondary to temozolomide. J Neurooncol 91:237-239, 2009.

Baskin JL, Reiss U, Wilimas J, Metzger ML, Ribeiro RC, Pui C-H, Howard SC. Management of occlusion and thrombosis associated with long-term indwelling central venous catheters. Lancet 374:159-169, 2009.

Reiss UM. Is an increased hematocrit at birth a trigger for UVC-related thrombosis in preterm very low birth weight neonates? Pediatr Blood Cancer 52:3-4, 2009.

Sanchez GL, Reiss UM, de Alarcon PA. Risk of thrombosis with anomalies of the inferior vena cava and factor V Leiden. Case report and review. Pediatr Blood Cancer 50:731, 2008.

Basran R, Reiss U, Luo H, Ware R, Chui D. β-thalassemia intermedia due to compound heterozygosity for two β-globin gene promoter mutations, including a novel TATA box deletion. Pediatr Blood Cancer 50:363-366, 2008.

Reiss UM, Bensimhon P, Zimmerman SA, Ware RE. Hydroxyurea therapy for management of secondary erythrocytosis in cyanotic congenital heart disease. Am J Hematol 82:740-743, 2007.

Wilson MW, Hoehn ME, Haik BG, Rieman M, Reiss U. Low-dose cyclophosphamide and interferon alfa 2a for the treatment of capillary hemangioma of the orbit. Ophthalmology 114:1007-1011, 2007.

Reiss U, Oskouian B, Zhou J, Gupta V, Sooriyakumaran P, Kelly S, Wang E, Merrill AH, Saba JD. Sphingosine phosphate lyase enhances stress-induced ceramide generation and apoptosis. J Biol Chem 279:1281-1290, 2004.

Reiss U, Cowan M, McMillan A, Horn B. Hepatic veno-occlusive disease in blood and bone marrow transplantation in children and young adults: incidence, risk factors and outcome in a cohort of 241 patients. J Pediatr Hematol Oncol 24:746-750, 2002.

Horn B, Reiss U, Matthay K, McMillan A, Cowan M. Veno-occlusive liver disease in children with solid tumors undergoing autologous hematopoietic progenitor cell transplantation: the high incidence of disease in patients with neuroblastoma. Bone Marrow Transplant 29:409-415, 2002.

Müller SM, Schulz AS, Reiss UM, Schwarz K, Schreiner T, Wiesneth M, Debatin K-M, Friedrich W. Definition of a critical T cell threshold for prevention of GVHD after HLA non-identical PBPC transplantation in children. Bone Marrow Transplant 24:575-581, 1999.

Reiss U, Hofweber K, Herterich R, Waldherr R, Bohnert E, Jung E, Schärer K. Nephrotic syndrome and hypertensive crisis in Cockayne syndrome. Pediatr Nephrol 10:602-605, 1996.

Reiss U, Wingen A-M, Mehls O, Schärer K. Mortality trends in pediatric patients with chronic renal failure. Pediatr Nephrol 10:41-45, 1996

Schärer K, Reiss U, Mehls O, Gretz N, Möhring S, Pomer S, Staehler G, Opelz G. Changing patterns of chronic renal failure and renal replacement therapy in children and adolescents: a 20 year single center study. Eur J Pediatr 152:166-171, 1993.

Reiss U, Schaefer F, Daniel V, Opelz G, Schärer K. Diagnostische Wertigkeit des löslichen Interleukin-2-Rezeptors (sIL-2R) im Plasma bei chronischer Niereninsuffizienz und nach Nierentransplantation im Kindes- und Jugendalter [Diagnostic significance of soluble interleukin-2-receptor (sIL-2R) in plasma in chronic renal failure and after kidney transplantation in children and adolescents]. Zeitschrift für Transplantationsmedizin Nr 4:191-199, 1991.

Reiss U. Nierenersatztherapie bei Kindern und Jugendlichen an der Universitätskinderklinik Heidelberg 1969-1988. Inaugural dissertation [Renal replacement therapy in children and adolescents at the Children’s Hospital University of Heidelberg. Medical thesis]. 1990.

Last update: March 2013