Stacey L. Schultz-Cherry, PhD
Stacey L. Schultz-Cherry, PhD

Stacey L. Schultz-Cherry, PhD

Member, St. Jude Faculty

  • Deputy Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds



BS – University of Wisconsin, Platteville, Wisconsin
PhD – University of Alabama, Birmingham, Alabama

Research Interests

  • Influenza Virus Pathogenesis
  • Astrovirus Pathogenesis
  • Novel Vaccines and Therapeutics
  • Microbial Co-Infections

Selected Publications

Cline TD, Karlsson EA, Seufzer BJ, Schultz-Cherry S. The hemagglutinin protein of highly pathogenic H5N1 influenza viruses overcomes an early block in the replication cycle to promote productive replication in macrophages. J Virol November 14, 2012.

Ngunjiri JM, Mohni KN, Sekellick MJ, Schultz-Cherry S, Webster RG, Marcus PI. Lethal H5N1 influenza viruses are not resistant to interferon action in human, simian, porcine or chicken cells. Nat Med 18(10):1456-1457, 2012.

Karlsson EA, Marcelin G, Webby RJ, Schultz-Cherry S. Review on the impact of pregnancy and obesity on influenza virus infection. Influenza Other Respi Viruses 6(6):449-460, 2012.

Fouchier RAM, Garcia-Sastre A, Kawaoka Y, Barclay WS, Bouvier NM, Brown IH, Capua I, Chen H, Compans RW, Couch RB, Cox NJ, Doherty PC, Donis RO, Feldmann H, Guan Y, Katz J, Klenk HD, Kobinger G, Liu J, Liu X, Lowen A, Metten-Leiter TC, Osterhaus ADME, Palese P, Peiris JSM, Perez DR, Richt JA, Schultz-Cherry S, Steel J, Subbarao K, Swayne DE, Takimoto T, Tashiro M, Taubenberger JK, Thomas PG, Tripp RA, Tumpey TM, Webby RJ, Webster RG. Pause on avian flu transmission research. Science 335(6067):400-401, 2012.

Schultz-Cherry S, Olsen CW, Easterday BC. History of swine influenza. Curr Top Microbiol Immunol January 21, 2012.

O'Brien KB, Vogel P, Duan S, Govorkova EA, Webby RJ, McCullers JA, Schultz-Cherry S. Impaired wound healing predisposes obese mice to severe influenza virus infection. J Infect Dis 205(2):252-261, 2011.

De Benedictis P, Schultz-Cherry S, Burnham A, Cattoli G. Astrovirus infections in humans and animals - molecular biology, genetic diversity, and interspecies transmissions. Infect Genet Evol 85(23):12262-70, 2011.

Cline TD, Karlsson EA, Freiden P, Seufzer BJ, Rehg JE, Webby RJ, Schultz-Cherry S. Increased pathogenicity of a reassortant 2009 pandemic H1N1 influenza virus containing an H5N1 hemagglutinin. J Virol 85(23):12262-122701529-44, 2011.

Jones JC, Settles EW, Brandt CR, Schultz-Cherry S. Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine. Vaccine August 9, 2011.

O'Brien K, Schultz-Cherry S, Knoll LJ. Parasite-mediated upregulation of NK cell-derived IFN? protects against severe HPAI H5N1 influenza virus infection. J Virol July 6, 2011.

Smith AM, Qualls JE, O'Brien K, Balouzian L, Johnson PF, Schultz-Cherry S, Smale ST, Murray PJ. A distal enhancer in IL12b is the target of transcriptional repression by the STAT3 pathway and requires the basic leucine zipper (B-ZIP) protein NFIL3. J Biol Chem 286(26):23581-90, 2011.

O'Brien KB, Morrison TE, Dundore DY, Heise MT, Schultz-Cherry S. A protective role for complement C3 protein during pandemic 2009 H1N1 and H5N1 influenza A virus infection. PLoS One 6(3):e17377, 2011.

Jones JC, Settles EW, Brandt CR, Schultz-Cherry S. Identification of the minimal active sequence of an anti-influenza peptide. Antimicrob Agents Chemother January 10, 2011.

Carlson CM, Turpin EA, Moser LA, O'Brien KB, Cline TD, Jones JC, Tumpey TM, Katz JM, Kelley LA, Gauldie J, Schultz-Cherry S. Transforming growth factor-?: activation by neuraminidase and role in highly pathogenic H5N1 influenza pathogenesis. PLoS Pathog 6(10):e1001136, 2010.

Schultz-Cherry S, Jones JC. Influenza vaccines: the good, the bad, and the eggs. Adv Virus Res 77:63-84, 2010.

McCullers JA;, Van De Velde LA, Schultz RD, Mitchell CG, Halford CR, Boyd KL, Schultz-Cherry S. Seroprevalence of seasonal and pandemic influenza A viruses in domestic cats. Arch Virol September 28, 2010.

Aguilar-Yanes JM, Portillo-Lara R, Mendoza-Ochoa GI, Garcia-Echauri SA, Lopes-Pacheco F, Bulnes-Abundis D, Salgado-Gallegos J, Lara-Mayorga IM, Webb-Vargas Y, Leon-Angel FO, Rivero-Aranda RE, Oropeza-Almazan Y, Ruiz-Palacios GM, Zertuche-Guerra MI, DuBois RM, White SW, Schultz-Cherry S, Russell CJ, Alvarez MM. An influenza A/H1N1/2009 hemagglutinin vaccine produced in escherichia coli. PLoS One 5(7): e11694, 2010.

Alvarez MM, Lopez-Pacheco F, Aguilar-Yanez JM, Portillo-Lara R, Mendoza-Ochoa GI, Garcia-Echauri S. Freiden P, Schultz-Cherry S, Zertuche-Guerra MI, Bulnes-Abundis D, Salgado-Gallegos J, Elizondo-Montemayor L, Hernandez-Torre M. Specific recognition of influenza A/H1N1/2009 antibodies in human serum: a simple virus-free ELISA method. PLoS One 5(4): e10176, 2010.

Jones JC, Schultz-Cherry S. Developing a Vaccine for Pandemic Influenza: Is it Possible? Controversies in Science and Technology 2009 (in press).

Moser LA, Schultz-Cherry S. Suppression of Astrovirus Replication by an ERK1/2 Inhibitor. J Virol 82:7475-7482, 2008.

Strain E, Kelley L, Schultz-Cherry S, Muse S, Koci M. Genomic Analysis of Closely Related Astroviruses. J Virol 82:5099-5103, 2008.

Moser LA, Carter M, Schultz-Cherry S. Astrovirus Increases Epithelial Barrier Permeability Independently of Viral Replication. J Virol 81:11937-11945, 2007.

Jones JA, Brandt C, Schultz-Cherry S. Influenza Combat: Expanding Our Arsenal with Peptide Antivirals. Future Virology 2:231-233, 2007.

Jones J, Turpin EA, Bultmann H, Brandt C, Schultz-Cherry S. Inhibition of influenza virus infection by a novel antiviral peptide that targets viral attachment to cells. J Virol 80:11960-11967, 2006.

Schultz-Cherry S, McCullers JA. A step closer to meeting the threat of avian influenza. PLos Medicine 3:e375, 2006.

Tumpey TM, Garcia-Sastre A, Taubenberger JK, Palese P, Swayne DE, Pantin-Jackwood MJ, Schultz-Cherry S, van Rooijen N, Katz JM, Basler CF. Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: a functional role of alveolar macrophages and neutrophils in limiting virus replication and disease severity in mice. J Virol 79:14933-14944, 2005.

Schultz-Cherry S. Guest Editorial: update on enteric viruses. Viral Immunol 18:1-3, 2005.

Turpin E, Luke K, Jones J, Tumpey T, Konan K, Schultz-Cherry S. Influenza virus infection increases p53 activity: role in cell death and viral replication. J Virol 79:8802-8811, 2005.

Last update: December 2012