Watch the story of our founding.
Since opening in 1962, St. Jude Children’s Research Hospital has become a world leader in the research and treatment of childhood catastrophic diseases.
The story of St. Jude reflects purpose, persistence and progress.
How we began
The origins of St. Jude trace back to our founder, entertainer Danny Thomas, and his belief that “no child should die in the dawn of life.” From the start, St. Jude was dedicated to finding cures for some of the most difficult-to-treat diseases of childhood. It was a place where scientists and doctors worked with purpose to understand disease; move discoveries from the lab to the bedside; and save children, even when the prevailing wisdom was that these children could not be saved. As a research hospital, St. Jude shared these discoveries so more children could benefit.
Equally important was another revolutionary idea: Families should be able to focus on helping their children heal, not on how they would pay for treatment. These ideas created a model unlike any other — one that continues to shape everything we do today.
To bring that vision to life, Danny Thomas created the American Lebanese Syrian Associated Charities (ALSAC), the fundraising and awareness organization for St. Jude. ALSAC has helped the organization grow since its earliest days.
Dig deeper into the St. Jude story
Danny Thomas and the founding of St. Jude
After Danny Thomas became one of the biggest stars of his time, he took on a new role as founder of St. Jude. Learn more about Danny and how St. Jude came to be.
Pioneering racial integration
At a time when segregation was still common, St. Jude became the first fully integrated children's hospital in the South. Read how people from many backgrounds have helped shape our mission.
Our legacy of leadership
Our first director, Donald Pinkel, MD, revolutionized leukemia treatment and set high standards for research and patient care that guide us to this day. Learn about Dr. Pinkel and other leaders who helped St. Jude make a global impact.
The history of ALSAC
ALSAC is the fundraising and awareness organization for St. Jude; its sole mission is to raise the funds and awareness necessary to operate and maintain the hospital. Discover the origins of ALSAC and how it continues to support St. Jude today.
60+ years of St. Jude
St. Jude was built on the belief that scientific discovery can change the future for children. See how we've grown over more than 60 years in our effort to see that no child dies in the dawn of life.
1960s
Building a new model
We opened our doors with a bold belief: Research and patient care should advance together. Although St. Jude started small, that vision continues to expand today, scaling its impact to affect outcomes for more children.
1970s
Proving what is possible
We helped show that childhood diseases once deemed untreatable could be cured with science, persistence and innovation.
1980s
Growing stronger
We invested in the people, programs and facilities needed to support future discoveries.
1990s
Looking beyond the cure
As more children survived, we helped people better understand the long-term needs of patients.
2000s
Moving research forward
New tools transformed the pace of research. We focused on understanding disease at its biological roots. This offered new possibilities for more precise treatments.
2010s
Unlocking the genome
Advances in genomics and precision medicine opened new frontiers. We helped lead efforts to understand the genetic drivers of childhood cancer. We shared those insights with scientists around the world.
2020s
Reaching more children
Today, St. Jude works with partners around the world to share knowledge and improve care for children everywhere.
Your gift supports tomorrow's discoveries
Since opening our doors, we have remained grounded in our founding values. Danny Thomas believed that children with life-threatening diseases deserved both the best science and the greatest compassion. Today, we're continuing that legacy with our strategic plan and the expansion of St. Jude Global.
Unlike other hospitals, the majority of funding for St. Jude comes from generous donors. Your support means St. Jude can give our doctors and researchers the tools and technology they need to make the next groundbreaking discovery.
More to discover
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The impact of St. Jude
Since 1962, St. Jude has been advancing research and improving care and survival rates for kids with cancer and other life-threatening diseases.
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Connect with us
St. Jude offers several ways to connect with our mission — from understanding where we operate, to exploring the campus experience, to engaging through official digital channels.
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What does St. Jude do?
St. Jude gives kids with cancer and other life-threatening diseases the chance they deserve. We're dedicated to providing the best care for patients and leading the research that leads to cures.