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Our purpose

St. Jude is leading the way the world understands, treats and defeats childhood cancer and other life-threatening diseases. 

 
Volunteers holding open doors to welcome vistors to St. Jude
 
 

Our purpose is clear: Finding cures. Saving children.®

 
 

St. Jude exists to solve the most serious problems facing children, advancing cures and prevention through research, exceptional care, and an unwavering commitment to families.

As a research institution, children’s hospital, a degree-granting medical center and a trusted nonprofit, we work to ensure our discoveries reach children everywhere, learning from those treated on our campus in Memphis, Tennessee.

 
 
Historical photo of Danny Thomas holding a child.

St. Jude founder Danny Thomas, with patients

 

The spirit behind our purpose

When Danny Thomas founded St. Jude, he created a unique children’s hospital that became a research center for the world, treating children regardless of race, religion or financial status. 

The greatest reward is the smiles on the faces of the children whose lives you've helped save.

Danny Thomas, founder

St. Jude has helped push the overall childhood cancer survival rate in the U.S. from 20% in 1962 to more than 80% today. Despite progress, pediatric cancer remains the leading cause of death by disease among U.S. children ages 1 to 14. As our knowledge advances, we continue to deepen our commitment to accelerating progress globally.

See Our Mission, Vision & Values

 
 

Our purpose in action

 St. Jude is in the midst of a six-year, historic $12.9 billion strategic plan. Since its launch, we’ve made gains across the plan’s five focus areas: fundamental science, childhood cancer, childhood catastrophic diseases, global impact, and people & place. Here are just a few highlights:

 
Icon of a beaker.
 
 

Opening of the Inspiration4 Advanced Research Center

In 2021, we opened the Inspiration4 Advanced Research Center, which accommodates up to 1,000 employees and has labs devoted to immunology, neurobiology, cell and molecular biology, gene editing, advanced microscopy, immunotherapy and other fields.

 
Icon of children.
 
 

Launch of Global Platform for Access to Childhood Cancer Medicines

The Global Platform for Access to Childhood Cancer Medicines is a collaboration between St. Jude, the World Health Organization and other global partners, to provide safe and effective cancer medicines to approximately 120,000 children worldwide. Medicine deliveries commenced in 2025.

 
Icon of a doctor.
 
 

Expansion of the St. Jude Graduate School degree offerings

The St. Jude Graduate School of Biomedical Sciences began offering a master’s degree in data science across four degree-granting programs. 31 students earned degrees in 2025.

 

View All Milestones

The St. Jude strategic plan sets measurable goals for how we will advance science, expand global reach and improve survival for children facing catastrophic disease in the years ahead.

 
 

Leaders advancing our purpose

Advancing our mission requires purposeful leadership. St. Jude's executive leaders and governing bodies help ensure the institution remains focused on what matters most: accelerating progress for children everywhere, stewarding resources responsibly and honoring the trust placed in us by patients, families, supporters and partners.

View Our Leadership Team

 
 
 
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