Laurea (MSc) – Medical School, University of Milano, Italy
PhD – Max Planck Institute for Cell Biology and Genetics, Dresden, Germany
Postdoctoral Studies – Harvard Medical School/HHMI, Boston, Massachusetts
Honors & Awards
- 2013 New Scholar in Aging Award, Ellison Medical Foundation
- 2011 AFAR/GE Healthcare Junior Investigator Award for Excellence in Imaging and Aging Research
- 2010 Ellison Medical Foundation/AFAR postdoctoral fellowship
- 2006 European Doctorate in Biotechnologies
- Role of protein homeostasis and stress sensing in skeletal muscle aging
- Mechanisms controlling skeletal muscle mass and function during aging and age-related diseases
- Interconnection of muscle and systemic aging via myokine signaling
- Intertissue communication during aging
- Drosophila models of human disease
Patel VK, Demontis F. GDF11/Myostatin and aging. Aging May;6(5):351-352, 2014.
Demontis F, Patel VK, Swindell WR, Perrimon N. Intertissue control of the nucleolus via a myokine-dependent longevity pathway. Cell Reports June 12;7(5):1481-1494, 2014.
Piccirillo R, Demontis F, Perrimon N, Goldberg AL. Mechanisms of muscle growth and atrophy in mammals and Drosophila. Developmental Dynamics June;7(5):1-14, 2014.
Hunt LC, Demontis F. Whole-mount immunostaining of Drosophila skeletal muscle. Nature Protocols Dec;8(12):2496-501, 2013.
Demontis F, Piccirillo R, Goldberg AL, Perrimon N. The influence of skeletal muscle on systemic aging and lifespan. Aging Cell Dec;12(6):943-9, 2013.
Demontis F, Piccirillo R, Goldberg AL, Perrimon N. Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models. Disease Modelels & Mechanisms Nov;6(6):1339-52, 2013.
Katewa SD, Demontis F, Kolipinski M, Hubbard A, Gill MS, Perrimon N, Melov S, Kapahi P. Intra-myocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Cell Metabolism Jul 3;16(1):97-103, 2012.
Demontis F, Perrimon N. FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell Nov 24;143(5):813-25, 2010.
Demontis F, Perrimon N. Integration of InR/FOXO signaling and dMyc activity during muscle growth regulates body size. Development Mar;136(6):983-93, 2009.
Last update: June 2014