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Randall T. Hayden, MD
Randall T. Hayden, MD

Randall T. Hayden, MD

Member, St. Jude Faculty

  • Director, Clinical and Molecular Microbiology
  • Medical Director, Clinical Pathology
  • Director, Global Pathology and Laboratory Medicine
  • Fellow of the Infectious Diseases Society of America



MD – University of Illinois College of Medicine (1989)

Research Interests

  • Application of molecular diagnostic techniques to clinical microbiology
  • Diagnostic microbiology of the Immunocompromised Pediatric Host
  • Morphologic diagnosis of infectious diseases in tissue
  • Laboratory diagosis of infectious diseases in resource-limited settings

Testing of infectious pathogens in patient samples

Selected Publications

Brazelton de Cárdenas JN, Su Y, Rodriguez A, Hewitt C, Tang L, Garner CD, Hayden RT. Evaluation of Rapid Phenotypic Identification and Antimicrobial Susceptibility Testing in a Pediatric Oncology Center. Diagn Microbiol Infect Dis 89(1):52-57, 2017.

Hayden RT, Sun Y, Tang L, Procop GW, Hillyard DR, Pinsky BA, Young SA, Caliendo AM. Progress in Quantitative Viral Load Testing: Variability and Impact of the WHO Quantitative International Standards. J Clin Microbiol 55(2): 423-30, 2017.

Mohammad MN, Rodriguez A, Gu Z, Zhu H, Tang L, Sun Y, Schultz-Cherry S, Hayden RT, Adderson EE. Epidemiology of Diarrheal Illness in Pediatric Oncology Patients, J Pediatric Infect Dis Soc 6(3):275-280, 2017.

Hayden RT, Clinton LK, Hewitt C, Koyamatsu T, Sun Y, Ginger Jamison G, Perkins R, Tang L, Pounds S,  Bankowski MJ. Rapid Antimicrobial Susceptibility Testing Using Forward Laser Light Scatter Technology. J Clin Microbiol 54(10):2602-8, 2016. 

Hayden RT, Gu Z, Sam SS, Sun Y, Tang L, Pounds S, Caliendo AM. Comparative Performance of Reagents and Platforms for Quantitation of Cytomegalovirus DNA by Digital PCR. J Clin Microbiol 54(10):2602-8, 2016.

Preiksaitis JK, Hayden RT, Tong Y, Pang XL, Fryer JF, Heath AB, Cook L, Petrich AK, Yu B, Caliendo AM. Are We There Yet? Impact of the 1st International Standard for Cytomegalovirus DNA on the Harmonization of Results Reported on Plasma Samples. Clin Infect Dis 63(5):583-89, 2016.

Mukkada S, Kirby J, Apiwattanakul N, Hayden R, Caniza MA. Use of Fungal Diagnostics and Therapy in Pediatric Cancer Patients in Resource-limited Settings. Current Clinical Microbiology Reports 3(3):120-31, 2016.

Tang L, Sun, Y, Buelow D, Gu Z, Caliendo AM, Pounds S, Hayden RT. Quantitative Assessment of Commutability for Clinical Viral Load Testing Using a Digital PCR-based Reference Standard. J Clin Microbiol 54(6):1616-23, 2016.

Buelow D, Sun Y, Tang L, Gu Z, Pounds S, Hayden R. Comparative evaluation of Four Real-time PCR methods for the quantitative detection of EBV from whole blood specimens. J Mol Diag 85(1):23-5, 2016.

Suganda S, Tang L, Carr J, Sun Y, Pounds S, Hayden R. Comparative Evaluation of Whole Blood Versus Plasma for Quantitative Detection of Cytomegalovirus Using an Automated System. Diagn Microbiol Infect Dis 85(1):23-5, 2016.

Hayden RT, Preiksaitis J, Tong Y, Pang X, Sun Y, Tang L, Cook L, Pounds S, Fryer J, Caliendo AM. Commutability of the 1st WHO international Standard for Human Cytomegalovirus. J Clin Microbiol 53(10):3325-33, 2015.

Gu, Z, Zhu H, Rodriguez A, Mhaissen M, Schultz-Cherry S, Adderson E, Hayden RT. Comparative Evaluation of Broad-Panel PCR Assays for the Detection of Gastrointestinal Pathogens in Pediatric Oncology Patients. J Mol Dia 17(6):715-21, 2015.

Hayden RT, Gu Z, Sam SS, Sun Y, Tang L, Pounds S, Caliendo AM. Comparative Evaluation of Three Commercial Quantitative Cytomegalovirus Standards Using Digital and Real-Time PCR. J Clin Microbiol 53(5):1500-5, 2015.

Hayden RT, Gu Z, Liu W, Lovins R, Kasow K, Woodard P, Srivistava K, Leung W. Risk Factors for Haemorrhagic Cystitis in Paediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients. Transpl ID 17(2):234-41, 2015.

Srinivasan A, Klepper C, Sunkara A, Kang G, Carr J, Gu Z, Leung W, Hayden RT. Impact of adenoviral stool load on adenoviremia in pediatric hematopoietic stem cell transplant recipients. Ped Inf Dis J 34(6):562-5, 2015.

Gu Z, Buelow DR, Petraitiene R, Petraitis V, Walsh TJ, Hayden RT. Quantitative Multiplexed Detection of Common Pulmonary Fungal Pathogens Using Labeled Primer PCR. Arch Path Lab Med 138(11):1474-80, 2014.

Hayden RT, Shahbazian MD, Valsamakis A, Boonyaratanakornkit J, Cook L, Pang XL, Preiksaitis JK, Schӧnbrunner ER, Caliendo AM. Multicenter evaluation of a commercial cytomegalovirus quantitative standard:  effects of commutability on interlaboratory concordance. J Clin Micro 51(11):3811-7, 2013.

Razonable RR, Hayden RT. Clinical Utility of Viral Load in the Management of Cytomegalovirus Infection after Solid Organ Transplantation. Clin Micro Rev 26(4):703-27, 2013.

Massire C, Buelow DR, Zhang SX, Lovari R, Matthews HE, Toleno DM, Ranken RR, Hall TA, Metzgar D, Sampath R, Blyn LB, Ecker DJ, Gu Z, Walsh TJ, Hayden RT. PCR Followed by Electrospray Ionization Mass Spectrometry for Broad Range Identification of Fungal Pathogens. J Clin Micro 51(2):540-62013, 2013.

Hayden RT, Gu Z, Ingersoll J, Abdul-Ali D, Shi L, Pounds S, Caliendo AM. Comparison of Droplet Digital PCR to Real-Time PCR for Quantitative Detection of Cytomegalovirus. J Clin Micro 51(2):540-6, 2013.

Last update: October 2017