Jamie Maciaszek, PhD

Jamie Maciaszek, PhD

  • Clinical Research Associate II

Departments

Divisions

Education

BS- Bioengineering, Lehigh University, Bethlehem, PA
PhD- Biomedical Engineering, University of Connecticut, Storrs, CT

Honors and Awards

  • 2015-2017 National Institutes of Health Loan Repayment Program, Extramural Award
  • 2014-2016 Academic Programs Special Fellowship, St. Jude
  • 2011-2013 American Heart Association Predoctoral Fellow, Founder’s Affiliate

Research Interests

I joined St. Jude in January 2014 as a postdoctoral fellow in Experimental Hematology. Through my work modeling genetic drivers of pediatric ALL, I became very interested in identifying and understanding cancer risk variants to expand the use of precision-medicine approaches to cancer. 

Selected Publications

Liu Y, Easton J, Shao Y, Maciaszek J, Wang Z, Wilkinson MR, McCastlain K, Edmonson M, Pounds SB, Shi L, Zhou X, Ma X, Sioson E, Li Y, Rusch M, Gupta P, Pei D, Cheng C, Smith MA, Auvil JG, Gerhard DS, Relling MV, Winick NJ, Carroll AJ, Heerema NA, Raetz E, Devidas M, Willman CL, Harvey RC, Carroll WL, Dunsmore KP, Winter SS, Wood BL, Sorrentino BP, Downing JR, Loh ML, Hunger SP, Zhang J, Mullighan CG. The Genomic Landscape of T-Lineage Acute Lymphoblastic Leukemia. Nature Genetics 49:1211-1218, 2017.

Wandersee NJ, Maciaszek JL, Giger KM, Hanson MS, Zheng S, Guo Y, Mickelson B, Hillery CA, Lykotrafitis G, Low PS, Hogg N. Dietary supplementation with docosohexanoic acid (DHA) increases red blood cell membrane flexibility in mice with sickle cell disease. Blood Cells, Molecules, and Diseases 54:183-188, 2015.

Maciaszek JL, Partola K, Zhang J, Andemariam B, Lykotrafitis G. Single-cell force spectroscopy as a technique to quantify human red blood cell adhesion to subendothelial laminin. Journal of Biomechanics 47:3855-3861, 2014.

Maciaszek, JL, Andemariam, B, Lykotrafitis, G, AKAP-dependent modulation of BCAM/Lu adhesion on normal and sickle cell disease RBCs revealed by force nanoscopy. Biophysical J 106:1258-1267, 2014.

Maciaszek JL, Soh H, Walikonis RS, Tzingounis AV, Lykotrafitis G. Topography of Native SK Channels Revealed by Force Nanoscopy in Living Neurons. The Journal of Neuroscience 32:11435-11440, 2012. Recommended by Faculty of 1000.

Maciaszek JL, Lykotrafitis G. Sickle cell trait human erythrocytes are significantly stiffer than normal, Journal of Biomechanics 44:657-661, 2011.

Last update: September 2017