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Jason Myers, MS

Jason Myers, MS

  • Bioinformatics Analyst III, Genetics

Education

MS, Bioinformatics - Rochester Institute of Technology, Rochester, NY
BS, Bioinformatics - Rochester Institute of Technology, Rochester, NY
AS, Computer Science - Corning Community College, Corning, NY

About

Jason Myers is a bioinformatician specializing in next-generation sequencing data analysis and genetics. In order to accomplish large scale data analyses, he designs, tests, and validates software and software pipelines in high-performance computing environments.

Research Interests

  • Coding and Non-Coding Variant Prioritization and Interpretation
  • Hodgkins Lymphoma Germline Predispostion
  • Amyotrophic lateral scleroris (ALS)

Selected Publications

Azadniv M, Myers JR, McMurray HR, Guo N, Rock P, Coppage ML, Ashton J, Becker MW, Calvi LM, Liesveld JL. Bone marrow mesenchymal stromal cells from acute myelogenous leukemia patients demonstrate adipogenic differentiation propensity with implications for leukemia cell support. Leukemia. 2019 Sep 6;. doi: 10.1038/s41375-019-0568-8. PMID: 31492897.

Kurosaki T, Miyoshi K, Myers JR, Maquat LE. NMD-degradome sequencing reveals ribosome-bound intermediates with 3'-end non-templated nucleotides. Nat Struct Mol Biol. 2018 Oct;25(10):940-950. doi: 10.1038/s41594-018-0132-7. Epub 2018 Oct 1. PMID: 30275517.

Pei S, Minhajuddin M, Adane B, Khan N, Stevens BM, Mack SC, Lai S, Rich JN, Inguva A, Shannon KM, Kim H, Tan AC, Myers JR, Ashton JM, Neff T, Pollyea DA, Smith CA, Jordan CT. AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells. Cell Stem Cell. 2018 Jul 5;23(1):86-100.e6. doi: 10.1016/j.stem.2018.05.021. PMID: 29910151

Cho H, Rambout X, Gleghorn ML, Nguyen PQT, Phipps CR, Miyoshi K, Myers JR, Kataoka N, Fasan R, Maquat LE. Transcriptional coactivator PGC-1α contains a novel CBP80-binding motif that orchestrates efficient target gene expression. Genes Dev. 2018 Apr 1;32(7-8):555-567. doi: 10.1101/gad.309773.117. PMID: 29654059

Elbarbary RA, Miyoshi K, Hedaya O, Myers JR, Maquat LE. UPF1 helicase promotes TSN-mediated miRNA decay. Genes Dev. 2017 Jul 15;31(14):1483-1493. doi: 10.1101/gad.303537.117. PMID: 28827400

Elbarbary RA, Miyoshi K, Myers JR, Du P, Ashton JM, Tian B, Maquat LE. Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition. Science. 2017 May 26;356(6340):859-862. doi: 10.1126/science.aai9372. PMID: 28546213

Ho TC, LaMere M, Stevens BM, Ashton JM, Myers JR, O'Dwyer KM, Liesveld JL, Mendler JH, Guzman M, Morrissette JD, Zhao J, Wang ES, Wetzler M, Jordan CT, Becker MW. Evolution of acute myelogenous leukemia stem cell properties after treatment and progression. Blood. 2016 Sep 29;128(13):1671-8. doi: 10.1182/blood-2016-02-695312. Epub 2016 Jul 15. PMID: 27421961

Baras AS, Mitchell CJ, Myers JR, Gupta S, Weng LC, Ashton JM, Cornish TC, Pandey A, Halushka MK. miRge - A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy. PLoS One. 2015;10(11):e0143066. doi: 10.1371/journal.pone.0143066. PMID: 26571139

Edholm ES, Albertorio Saez LM, Gill AL, Gill SR, Grayfer L, Haynes N, Myers JR, Robert J. Nonclassical MHC class I-dependent invariant T cells are evolutionarily conserved and prominent from early development in amphibians. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14342-7. doi: 10.1073/pnas.1309840110. Epub 2013 Aug 12. PMID: 23940320

Huang W, Li L, Myers JR, Marth GT. ART: a next-generation sequencing read simulator. Bioinformatics. 2012 Feb 15;28(4):593-4. doi: 10.1093/bioinformatics/btr708. PMID: 22199392

Full List of Publications

Last update: June 2020