Jamy C. Peng, PhD
Jamy C. Peng, PhD

Jamy C. Peng, PhD

Assistant Member, St. Jude Faculty



PhD – University of California at Berkeley, Berkeley, CA
Postdoctoral studies – Stanford University, Stanford, CA and Yale University, New Haven, CT

Honors & Awards

  • 2012 NIH K99/R00 Pathway to Independence Award
  • 2008 American Cancer Society Postdoctoral Fellowship
  • 2007 NIH Interdisciplinary Postdoctoral Training Grant in Regenerative Medicine

Research Interests

  • Proteins and RNAs in epigenetic programming of stem cell functions
  • Epigenetic mechanisms influencing gene expression changes
  • Epigenetic regulation of stem cell functions

Selected Publications

Klein JD, Qu C, Yang X, Fan Y, Tang C, Peng JC. C-Fos repression by Piwi regulates Drosophila ovarian germline formation and tissue morphogenesis. PLOS Genet 12(9): e1006281, 2016.

Peng JC*#, Valouev A#, Liu N, Lin H. Piwi negatively regulates Polycomb Group proteins in maintaining germline stem cells and oogenesis. *co-corresponding authors. # co-first authors. Nature Genetics 48(3):283-91, 2016. 

Peng JC, Lin H. Beyond transposons: the epigenetic and somatic functions of the Piwi-piRNA mechanism. Curr Opin Cell Biol 25(2):190-194, 2013.

Peng JC, Valouev A, Swigut T, Zhang J, Zhao Y, Sidow A, Wysocka J. Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell 139(7):1290-1302, 2009. *Highlighted in Cell Stem Cell, Genes & Development, and Faculty of 1000.

Peng JC, Karpen GH. Heterochromatic genome stability requires regulators of histone H3 K9 methylation. PLoS Genet 5(3):e1000435, 2009.

Peng JC, Karpen GH. Epigenetic regulation of heterochromatic DNA stability. Curr Opin Genet Dev 18(2):204-11, 2008.

Peng JC, Wysocka J. It takes a PHD to SUMO. Trends Biochem Sci 33(5):191-194, 2008.

Peng JC, Karpen GH. H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability. Nat Cell Biol 9(1):25-35, 2007. *Highlighted in Cell, Nat Cell Biol, and Faculty of 1000.

Gallie DR, Fortner D, Peng J, Puthoff D. ATP-dependent hexameric assembly of the heat shock protein Hsp101 involves multiple interaction domains and a functional C-proximal nucleotide-binding domain. J Biol Chem 277(42):39617-39626, 2002.

Last update: August 2016