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Brandon Triplett, MD
Brandon Triplett, MD

Brandon Triplett, MD

Member, St. Jude Faculty

  • Deputy Clinical Director
  • Chief, Bone Marrow Transplant Clinical Service



AS – Southeastern Illinois College, Harrisburg, Illinois
BA – Southern Illinois University, Carbondale, Illinois
MD – St. Louis University School of Medicine, St. Louis, Missouri
Pediatric Residency – St. Louis University School of Medicine, St. Louis, Missouri
Pediatric Hematology-Oncology Fellowship – St. Jude Children’s Research Hospital, Memphis, Tennessee

Honors & Awards

  • 2018  Joseph V. Simone, MD Golden Apple Award – St. Jude Children’s Research Hospital
  • 2017  Outstanding Physician Award – St. Jude Children’s Research Hospital
  • 2014  Southeastern Illinois College Distinguished Alumni
  • 2009  Honorary Freezer – St. Louis Cord Blood Bank
  • 2000  Most Likely to Cure a Major Disease Award – SLUSoM Class of 2000

Research Interests

  • Hematopoietic cell transplantation for high risk leukemia
  • Use of HLA-mismatched related (haploidentical) donors
  • Graft modification to reduce GVHD, but maintain GVL

Selected Publications

Aguilera V, Schaefer MR, Parris K, Long A, Triplett B, Phipps S. Psychosocial Outcomes of Parents in Pediatric Haploidentical Transplant: Parental Hematopoietic Cell Donation as a Double-Edged Sword. Bone Marrow Transplantation Epub 2022, Jan 10. doi: 10.1038/s41409-021-01547-9

Sharma A, Li Y, Huang S, Talleur AC, Suliman A, Qudeimat A, Srinivasan A, Mamcarz E, Madden R, Cheng C, Gottschalk S, Triplett BM. Outcomes of Pediatric Patients Who Relapse After First HCT For Acute Leukemia or MDS. Bone Marrow Transplantation Epub 2021 March 19; doi: 10.1038/s41409-021-01267-0. PMID: 33742153

Mamcarz E, Madden R, Qudeimat A, Srinivasan A, Talleur A, Sharma A, Suliman A, Maron G, Sunkara A, Kang G, Leung W, Gottschalk S, Triplett BM. Improved survival rate in T-cell depleted haploidentical hematopoietic cell transplantation over the last 15 years at a single institution. Bone Marrow Transplantation May;55(5):929-938, 2020. doi: 10.1038/s41409-019-0750-7. Epub 2019 Nov 18. PubMed PMID: 31740766; PubMed Central PMCID: PMC7202974

Sharma A, Kang G, Sunkara A, Inaba H, Jeha S, Cross SJ, Geiger T, Triplett B. Haploidentical Donor Transplantation Using a Novel Clofarabine-Containing Conditioning Regimen for Very High-Risk Hematologic Malignant Neoplasms. Journal Pediatric Hematology Oncology 40:e479-e485, 2018. PMID:29750747. DOI: 10.1097/MPH.0000000000001222

Triplett BM, Muller B, Kang G, Li Y, Cross SJ, Moen J, Cunningham L, Janssen W, Mamcarz E, Shook DR, Srinivasan A, Choi JK, Hayden RT, Leung W. Selective T-cell depletion targeting CD45RA reduces viremia and enhances early T-cell recovery compared to CD3-targeted T-cell depletion. Transplant Infectious Disease Feb;20(1), 2018. PMID: 29178554. DOI: 10.1111/tid.12823

Triplett BM, Shook DR, Eldridge P, Li Y, Kang G, Dallas M, Hartford C, Srinivasan S, Chan WK, Suwannasaen D, Inaba H, Merchant TE, Pui CH, Leung W. Early Immune Reconstitution Recapitulating CD45RA-depleted Haploidentical Graft Content in Patients with Hematologic Malignancies. Bone Marrow Transplantation 50(7):968-977, 2015. PubMed PMID: 25665048; DOI: 10.1038/bmt.2014.324

Triplett B, Handgretinger R, Pui CH, Leung W. KIR-incompatible hematopoietic-cell transplantation for poor prognosis infant acute lymphoblastic leukemia. Blood 107(3):1238-9, 2006. PubMed PMID: 19212329, DOI: 10.1038/leu.2009.21

Full List of publications

Last update: October 2022