Richard Webby, PhD
Richard J. Webby, PhD

Richard J. Webby, PhD

Member, St. Jude Faculty

  • Director, World Health Organization Collaborating Centre for Studies on the Ecology of Influenza in Animals and Birds

Departments

Education

PhD – University of Otago, New Zealand

Honors & Awards

  • 2011 Work highlighted in Nature Magazine: Nature 480(7376):S4-5, 2011. Q&A: The flu catcher. An interview with Richard Webby
  • 2010-present World Organisation for Animal Health/Food and Agriculture Organization of the United Nations Swine Influenza Expert Group Member
  • 2010 Special Recognition Award “In honor of extraordinary work in H1N1 influenza research,” National Institute of Allergy and Infectious Diseases, Division of Microbiology and Infectious Diseases
  • 2008-present Member Influenza Advisory Committee, US National Pork Board
  • 2004 Research Leader in Public Health and Epidemiology, Scientific American 50

Research Interests

  • Influenza virus ecology
  • Influenza vaccination
  • Influenza virus pathogenicity
  • Determinants of host susceptibility to influenza

Selected Publications

Most significant publications

Jeevan T, Darnell D, Gradi EA, Benali Y, Kara R, Guetarni D, Rubrum A, Seiler PJ, Crumpton JC, Webby RJ, Derrar F. A(H9N2) influenza viruses associated with chicken mortality in outbreaks in Algeria 2017. Influenza Other Respir Viruses. Sep 3. doi: 10.1111/irv.12675. [Epub ahead of print] 2019 PubMed PMID: 31478603.

Kandeil A, Gomaa M, Nageh A, Shehata MM, Kayed AE, Sabir JSM, Abiadh A, Jrijer J, Amr Z, Said MA, Byarugaba DK, Wabwire-Mangen F, Tugume T, Mohamed NS, Attar R, Hassan SM, Linjawi SA, Moatassim Y, Kutkat O, Mahmoud S, Bagato O, Shama NMA, El-Shesheny R, Mostafa A, Perera RA, Chu DK, Hassan N, Elsokary B, Saad A, Sobhy H, El Masry I, McKenzie PP, Webby RJ, Peiris M, Makonnen YJ, Ali MA, Kayali G. Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Dromedary Camels in Africa and Middle East. Viruses. Aug 5;11(8). pii: E717. 2019 doi:10.3390/v11080717. PubMed PMID: 31387326.

Cohen L, Fiore-Gartland A, Randolph AG, Panoskaltsis-Mortari A, Wong SS, Ralston J, Wood T, Seeds R, Huang QS, Webby RJ, Thomas PG, Hertz T. A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls. Front Immunol. 2019 Jun 18;10:1338. doi:10.3389/fimmu.2019.01338. eCollection 2019. PubMed PMID: 31275311; PMCID: PMC6594355.

Barman S, Turner JCM, Hasan MK, Akhtar S, El-Shesheny R, Franks J, Walker D, Seiler P, Friedman K, Kercher L, Jeevan T, McKenzie P, Webby RJ, Webster RG, Feeroz MM. Continuing evolution of highly pathogenic H5N1 viruses in Bangladeshi live poultry markets. Emerg Microbes Infect. 2019;8(1):650-661. doi:10.1080/22221751.2019.1605845. PubMed PMID: 31014196; PMCID: PMC6493222.

Kandeil A, Gomaa M, Shehata M, El-Taweel A, Kayed AE, Abiadh A, Jrijer J, Moatasim Y, Kutkat O, Bagato O, Mahmoud S, Mostafa A, El-Shesheny R, Perera RA, Ko RL, Hassan N, Elsokary B, Allal L, Saad A, Sobhy H, McKenzie PP, Webby RJ, Peiris M, Ali MA, Kayali G. Middle East respiratory syndrome coronavirus infection in non-camelid domestic mammals. Emerg Microbes Infect. 2019;8(1):103-108. doi: 10.1080/22221751.2018.1560235. PubMed PMID: 30866764; PMCID: PMC6455111.

Pascua PNQ, Marathe BM, Vogel P, Webby RJ, Govorkova EA. Optimizing T-705 (favipiravir) treatment of severe influenza B virus infection in the immunocompromised mouse model. J Antimicrob Chemother. 2019 Jan 30. doi:10.1093/jac/dky560. [Epub ahead of print] PubMed PMID: 30715325; PMCID: PMC6477984.

Kayed AS, Kandeil A, Gomaa MR, El-Shesheny R, Mahmoud S, Hegazi N, Fayez M, Sheta B, McKenzie PP, Webby RJ, Kayali G, Ali MA. Surveillance for avian influenza viruses in wild birds at live bird markets, Egypt, 2014-2016. Influenza Other Respir Viruses. 2019 Jul;13(4):407-414. doi:10.1111/irv.12634. Epub 2019 Feb 3. PubMed PMID: 30714323; PMCID: PMC6586179.

Kandeil A, Gomaa MR, Shehata MM, El Taweel AN, Mahmoud SH, Bagato O, Moatasim Y, Kutkat O, Kayed AS, Dawson P, Qiu X, Bahl J, Webby RJ, Karesh WB, Kayali G, Ali MA. Isolation and Characterization of a Distinct Influenza A Virus from Egyptian Bats. J Virol. 2019 Jan 4;93(2). pii: e01059-18. doi:10.1128/JVI.01059-18. Print 2019 Jan 15. PubMed PMID: 30381492; PMCID: PMC6321940.

Hermans D, Webby RJ, Wong SS. Atypical antibody responses to influenza. J Thorac Dis. 2018 Jul;10(Suppl 19):S2238-S2247. doi: 10.21037/jtd.2017.12.122. Review. PubMed PMID: 30116603; PubMed Central PMCID: PMC6072921.

Li L, Bowman AS, DeLiberto TJ, Killian ML, Krauss S, Nolting JM, Torchetti MK, Ramey AM, Reeves AB, Stallknecht DE, Webby RJ, Wan XF. Genetic Evidence Supports Sporadic and Independent Introductions of Subtype H5 Low-Pathogenic Avian Influenza A Viruses from Wild Birds to Domestic Poultry in North America. J Virol. 2018 Sep 12;92(19). pii: e00913-18. doi: 10.1128/JVI.00913-18. Print 2018 Oct 1. PubMed PMID: 30045988;  PMCID: PMC6146819.

Huang QS, Bandaranayake D, Wood T, Newbern EC, Seeds R, Ralston J, Waite B, Bissielo A, Prasad N, Todd A, Jelley L, Gunn W, McNicholas A, Metz T, Lawrence S, Collis E, Retter A, Wong SS, Webby R, Bocacao J, Haubrock J, Mackereth G, Turner N, McArdle B, Cameron J, Reynolds EG, Baker MG, Grant CC, McArthur C, Roberts S, Trenholme A, Wong C, Taylor S, Thomas P, Duque J, Gross D, Thompson MG, Widdowson MA; Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance (SHIVERS) Investigation Team . Risk Factors and Attack Rates of Seasonal Influenza Infection: Results of the Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance (SHIVERS) Seroepidemiologic Cohort Study. J Infect Dis. 2019 Jan 9;219(3):347-357. doi:10.1093/infdis/jiy443. PubMed PMID: 30016464.

El-Shesheny R, Franks J, Marathe BM, Hasan MK, Feeroz MM, Krauss S, Vogel P, McKenzie P, Webby RJ, Webster RG. Genetic characterization and pathogenic potential of H10 avian influenza viruses isolated from live poultry markets in Bangladesh. Sci Rep. 2018 Jul 16;8(1):10693. doi: 10.1038/s41598-018-29079-1. PubMed PMID: 30013138; PMCID: PMC6048039.

Kandeil A, Sabir JSM, Abdelaal A, Mattar EH, El-Taweel AN, Sabir MJ, Khalil AA, Webby R, Kayali G, Ali MA. Efficacy of commercial vaccines against newly emerging avian influenza H5N8 virus in Egypt. Sci Rep. 2018 Jun 26;8(1):9697. doi: 10.1038/s41598-018-28057-x. PubMed PMID: 29946159; PubMed Central PMCID: PMC6018731.

Wang ZJ, Kikutani Y, Nguyen LT, Hiono T, Matsuno K, Okamatsu M, Krauss S, Webby R, Lee YJ, Kida H, Sakoda Y. H13 influenza viruses in wild birds have undergone genetic and antigenic diversification in nature. Virus Genes. 2018 Aug;54(4):543-549. doi: 10.1007/s11262-018-1573-0. Epub 2018 May 23. PubMed PMID: 29796944.

El-Shesheny R, Feeroz MM, Krauss S, Vogel P, McKenzie P, Webby RJ, Webster RG. Replication and pathogenic potential of influenza A virus subtypes H3, H7, and H15 from free-range ducks in Bangladesh in mammals. Emerg Microbes Infect. 2018 Apr 25;7(1):70. doi: 10.1038/s41426-018-0072-7. PubMed PMID: 29691394; PMCID: PMC5915612.

Jones JC, Kumar G, Barman S, Najera I, White SW, Webby RJ, Govorkova EA. Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors. MBio. 2018 Apr 24;9(2). pii: e00430-18. doi: 10.1128/mBio.00430-18. Erratum in: MBio. 2018 Nov 13;9(6):. PubMed PMID: 29691337; PMCID: PMC5915737.

Krammer F, Fouchier RAM, Eichelberger MC, Webby RJ, Shaw-Saliba K, Wan H, Wilson PC, Compans RW, Skountzou I, Monto AS. NAction! How Can Neuraminidase-Based Immunity Contribute to Better Influenza Virus Vaccines? MBio. 2018 Apr 3;9(2). pii: e02332-17. doi: 10.1128/mBio.02332-17. Review. PubMed PMID: 29615508; PMCID: PMC5885027.

Kwon HI, Kim EH, Kim YI, Park SJ, Si YJ, Lee IW, Nguyen HD, Yu KM, Yu MA, Jung JH, Choi WS, Kwon JJ, Ahn SJ, Baek YH, Van Lai D, Lee OJ, Kim SW, Song MS, Yoon SW, Kim CJ, Webby RJ, Mo IP, Choi YK. Comparison of the pathogenic potential of highly pathogenic avian influenza (HPAI) H5N6, and H5N8 viruses isolated in South Korea during the 2016-2017 winter season. Emerg Microbes Infect. 2018 Mar 14;7(1):29. doi: 10.1038/s41426-018-0029-x. PubMed PMID: 29535296; PMCID: PMC5849756.

Kwon JJ, Choi WS, Jeong JH, Kim EH, Lee OJ, Yoon SW, Hwang J, Webby RJ, Govorkova EA, Choi YK, Baek YH, Song MS. An I436N substitution confers resistance of influenza A(H1N1)pdm09 viruses to multiple neuraminidase inhibitors without affecting viral fitness. J Gen Virol. 2018 Mar;99(3):292-302. doi:10.1099/jgv.0.001029. PubMed PMID: 29493493.

Kim H, Webster RG, Webby RJ. Influenza Virus: Dealing with a Drifting and Shifting Pathogen. Viral Immunol. 2018 Mar;31(2):174-183. doi:10.1089/vim.2017.0141. Epub 2018 Jan 26. Review. PubMed PMID: 29373086.

Koo BS, Kim HK, Song D, Na W, Song MS, Kwon JJ, Wong SS, Noh JY, Ahn MJ, Kim DJ, Webby RJ, Yoon SW, Jeong DG. Virological and pathological characterization of an avian H1N1 influenza A virus. Arch Virol. 2018 May;163(5):1153-1162. doi:10.1007/s00705-018-3730-0. Epub 2018 Jan 24. PubMed PMID: 29368065.

Tewawong N, Marathe BM, Poovorawan Y, Vongpunsawad S, Webby RJ, Govorkova EA. Neuraminidase inhibitor susceptibility and neuraminidase enzyme kinetics of human influenza A and B viruses circulating in Thailand in 2010-2015. PLoS One. 2018 Jan 11;13(1):e0190877. doi: 10.1371/journal.pone.0190877. eCollection 2018. PubMed PMID: 29324781; PMCID: PMC5764337.

Wong SS, DeBeauchamp J, Zanin M, Sun Y, Tang L, Webby R. H5N1 influenza vaccine induces a less robust neutralizing antibody response than seasonal trivalent and H7N9 influenza vaccines. NPJ Vaccines. 2017 Jun 8;2:16. doi:10.1038/s41541-017-0017-5. eCollection 2017. PubMed PMID: 29263872; PMCID: PMC5627238.

Beylkin D, Kumar G, Zhou W, Park J, Jeevan T, Lagisetti C, Harfoot R, Webby RJ, White SW, Webb TR. Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease. Sci Rep. 2017 Dec 7;7(1):17139. doi: 10.1038/s41598-017-17419-6. PubMed PMID: 29215062; PMCID: PMC5719402.

Araujo J, Petry MV, Fabrizio T, Walker D, Ometto T, Thomazelli LM, Scherer AL, Serafini PP, Neto IS, Krauss S, Webster RG, Webby RJ, Durigon EL. Migratory birds in southern Brazil are a source of multiple avian influenza virus subtypes. Influenza Other Respir Viruses. 2018 Mar;12(2):220-231. doi: 10.1111/irv.12519. Epub 2017 Dec 15. Erratum in: Influenza Other Respir Viruses. 2018 Jul;12(4):547. PubMed PMID: 29143465; PMCID: PMC5820415.

Wen F, Li L, Zhao N, Chiang MJ, Xie H, Cooley J, Webby R, Wang PG, Wan XF. A Y161F Hemagglutinin Substitution Increases Thermostability and Improves Yields of 2009 H1N1 Influenza A Virus in Cells. J Virol. 2018 Jan 2;92(2). pii: e01621-17. doi: 10.1128/JVI.01621-17. Print 2018 Jan 15. PubMed PMID: 29118117; PMCID: PMC5752953.

Wong SS, Oshansky CM, Guo XJ, Ralston J, Wood T, Seeds R, Newbern C, Waite B, Reynolds G, Widdowson MA, Huang QS, Webby RJ, Thomas PG; SHIVERS Investigation Team. Severe Influenza Is Characterized by Prolonged Immune Activation: Results From the SHIVERS Cohort Study. J Infect Dis. 2018 Jan 4;217(2):245-256. doi: 10.1093/infdis/jix571. PubMed PMID: 29112724.

Marathe BM, Mostafa HH, Vogel P, Pascua PNQ, Jones JC, Russell CJ, Webby RJ, Govorkova EA. A pharmacologically immunosuppressed mouse model for assessing influenza B virus pathogenicity and oseltamivir treatment. Antiviral Res. 2017 Dec;148:20-31. doi: 10.1016/j.antiviral.2017.10.021. Epub 2017 Oct 31. PubMed PMID: 29100887.

Choi WS, Jeong JH, Kwon JJ, Ahn SJ, Lloren KKS, Kwon HI, Chae HB, Hwang J, Kim MH, Kim CJ, Webby RJ, Govorkova EA, Choi YK, Baek YH, Song MS. Screening for Neuraminidase Inhibitor Resistance Markers among Avian Influenza Viruses of the N4, N5, N6, and N8 Neuraminidase Subtypes. J Virol. 2017 Dec 14;92(1). pii:e01580-17. doi: 10.1128/JVI.01580-17. Print 2018 Jan 1. PubMed PMID: 29046464; PMCID: PMC5730757.

Yoon SW, Wong SS, Zhu H, Chen R, Li L, Zhang Y, Guan Y, Webby RJ. Dysregulated T-Helper Type 1 (Th1):Th2 Cytokine Profile and Poor Immune Response in Pregnant Ferrets Infected With 2009 Pandemic Influenza A(H1N1) Virus. J Infect Dis. 2018 Jan 17;217(3):438-442. doi: 10.1093/infdis/jix328. PubMed PMID: 28973317; PMCID: PMC5853788.

Zanin M, Wong SS, Barman S, Kaewborisuth C, Vogel P, Rubrum A, Darnell D, Marinova-Petkova A, Krauss S, Webby RJ, Webster RG. Molecular basis of mammalian  transmissibility of avian H1N1 influenza viruses and their pandemic potential. Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11217-11222. doi: 10.1073/pnas.1713974114. Epub 2017 Sep 5. PubMed PMID: 28874549; PMCID: PMC5651783.

Sun H, Blackmon S, Yang G, Waters K, Li T, Tangwangvivat R, Xu Y, Shyu D, Wen F, Cooley J, Senter L, Lin X, Jarman R, Hanson L, Webby R, Wan XF. Zoonotic Risk, Pathogenesis, and Transmission of Avian-Origin H3N2 Canine Influenza Virus. J Virol. 2017 Oct 13;91(21). pii: e00637-17. doi: 10.1128/JVI.00637-17. Print 2017  Nov 1. Erratum in: J Virol. 2018 Mar 28;92 (8):. PubMed PMID: 28814512; PMCID: PMC5640866.

Barman S, Marinova-Petkova A, Hasan MK, Akhtar S, El-Shesheny R, Turner JC, Franks J, Walker D, Seiler J, Friedman K, Kercher L, Jeevan T, Darnell D, Kayali G, Jones-Engel L, McKenzie P, Krauss S, Webby RJ, Webster RG, Feeroz MM. Role of domestic ducks in the emergence of a new genotype of highly pathogenic H5N1 avian influenza A viruses in Bangladesh. Emerg Microbes Infect. 2017 Aug 9;6(8):e72. doi: 10.1038/emi.2017.60. PubMed PMID: 28790460; PMCID: PMC5583668.

Pascua PNQ, Mostafa HH, Marathe BM, Vogel P, Russell CJ, Webby RJ, Govorkova EA. Pathogenicity and peramivir efficacy in immunocompromised murine models of influenza B virus infection. Sci Rep. 2017 Aug 4;7(1):7345. doi:10.1038/s41598-017-07433-z. PubMed PMID: 28779075; PMCID: PMC5544712.

Kandeil A, Kayed A, Moatasim Y, Webby RJ, McKenzie PP, Kayali G, Ali MA. Genetic characterization of highly pathogenic avian influenza A H5N8 viruses isolated from wild birds in Egypt. J Gen Virol. 2017 Jul;98(7):1573-1586. doi:10.1099/jgv.0.000847. Epub 2017 Jul 19. PubMed PMID: 28721841; PMCID: PMC5817258.

Qiu X, Duvvuri VR, Gubbay JB, Webby RJ, Kayali G, Bahl J. Lineage-specific epitope profiles for HPAI H5 pre-pandemic vaccine selection and evaluation. Influenza Other Respir Viruses. 2017 Sep;11(5):445-456. doi:10.1111/irv.12466. Epub 2017 Aug 12. PubMed PMID: 28715148; PMCID: PMC5963872.

Kaplan BS, Torchetti MK, Lager KM, Webby RJ, Vincent AL. Absence of clinical disease and contact transmission of HPAI H5NX clade 2.3.4.4 from North America in experimentally infected pigs. Influenza Other Respir Viruses. 2017 Sep;11(5):464-470. doi: 10.1111/irv.12463. Epub 2017 Sep 2. PubMed PMID: 28688206; PMCID: PMC5596520.

Ducatez M, Sonnberg S, Crumpton JC, Rubrum A, Phommachanh P, Douangngeun B, Peiris M, Guan Y, Webster R, Webby R. Highly pathogenic avian influenza H5N1 clade 2.3.2.1 and clade 2.3.4 viruses do not induce a clade-specific phenotype in mallard ducks. J Gen Virol. 2017 Jun;98(6):1232-1244. doi:10.1099/jgv.0.000806. Epub 2017 Jun 20. PubMed PMID: 28631606; PubMed Central PMCID: PMC5825919.

El-Shesheny R, Barman S, Feeroz MM, Hasan MK, Jones-Engel L, Franks J, Turner J, Seiler P, Walker D, Friedman K, Kercher L, Begum S, Akhtar S, Datta AK, Krauss S, Kayali G, McKenzie P, Webby RJ, Webster RG. Genesis of Influenza A(H5N8) Viruses. Emerg Infect Dis. 2017 Aug;23(8):1368-1371. doi: 10.3201/eid2308.170143. Epub 2017 Aug 15. PubMed PMID: 28609260; PMCID: PMC5547793.

Webby RJ, Yang Z. The changing landscape of A H7N9 influenza virus infections in China. Lancet Infect Dis. 2017 Aug;17(8):783-784. doi:10.1016/S1473-3099(17)30337-7. Epub 2017 Jun 2. PubMed PMID: 28583579.

Sun H, Kaplan BS, Guan M, Zhang G, Ye J, Long LP, Blackmon S, Yang CK, Chiang , MJ, Xie H, Zhao N, Cooley J, Smith DF, Liao M, Cardona C, Li L, Wang GP, Webby R, Wan XF. Pathogenicity and transmission of a swine influenza A(H6N6) virus. Emerg Microbes Infect. 2017 Apr 12;6(4):e17. doi: 10.1038/emi.2017.3. PubMed PMID: 28400591; PMCID: PMC5457681.

Yang J, Shim SM, Nguyen TQ, Kim EH, Kim K, Lim YT, Sung MH, Webby R, Poo H. Poly-γ-glutamic acid/chitosan nanogel greatly enhances the efficacy and heterosubtypic cross-reactivity of H1N1 pandemic influenza vaccine. Sci Rep. 2017 Mar 21;7:44839. doi: 10.1038/srep44839. PubMed PMID: 28322289; PMCID: PMC5359587.

Wong SS, Duan S, DeBeauchamp J, Zanin M, Kercher L, Sonnberg S, Fabrizio T, Jeevan T, Crumpton JC, Oshansky C, Sun Y, Tang L, Thomas P, Webby R. The immune correlates of protection for an avian influenza H5N1 vaccine in the ferret model using oil-in-water adjuvants. Sci Rep. 2017 Mar 17;7:44727. doi: 10.1038/srep44727. PubMed PMID: 28303960; PMCID: PMC5381113.

Show More

Barman S, Krylov PS, Fabrizio T, Franks J, Turner JC, Seiler P, Wang D, Rehg J, Erickson GA, Gramer M, Webster RG, Webby RJ. Pathogenicity and transmissibility of North American triple reassortant swine influenza A viruses in ferrets. PLoS Pathogens 2012 (in press).

Ducatez DF, Webb A, Crumpton JC, Webby RJ. Long-term vaccine-induced heterologous protection against H5N1 influenza viruses in the ferret model. Influenza Other Respi Viruses 2012 (in press).

Hall JS, Krauss S, Franson JC, Teslaa JL, Nashold SW, Stallknecht DE, Webby RJ, Webster RG. Avian influenza in shorebirds: experimental infection of ruddy turnstones (Arenaria interpres) with avian influenza virus. Influenza Other Respi Viruses Apr 12, 2012. Epub ahead of print.

Kitikoon P, Vincent AL, Gauger PC, Schlink SN, Bayles DO, Gramer MR, Darnell D, Webby RJ, Lager KM, Swenson SL, Klimov A. Pathogenicity and transmission in pigs of the novel A(H3N2)v influenza virus isolated from humans and characterization of swine H3N2 viruses isolated in 2010-2011. J Virol Apr 4, 2012. Epub ahead of print.

Krauss S, Pryor SP, Raven G, Danner A, Kayali G, Webby RJ, Webster RG. Respiratory tract versus cloacal sampling of migratory ducks for influenza A viruses: are both ends relevant? Influenza Other Respi Viruses Mar 28, 2012. Epub ahead of print.

Huang K, Zhu H, Fan X, Wang J, Cheung CL, Duan L, Hong W, Liu Y, Li L, Smith DK, Chen H, Webster RG, Webby RJ, Peiris M, Guan Y. Establishment and lineage replacement of H6 influenza viruses in domestic ducks in southern China. J Virol Mar 21, 2012. Epub ahead of print.

Ma W, Liu Q, Bawa B, Qiao C, Qi W, Shen H, Chen Y, Ma J, Li X, Webby RJ, Garcia-Sastre A, Richt JA. The NA and M genes of the 2009 pandemic influenza H1N1 virus functionally cooperate to facilitate efficient replication and transmissibility in pigs. J Gen Virol Feb 15, 2012. Epub ahead of print.

Karlsson EA, Marcelin G, Webby RJ, Schultz-Cherry S. Review on the impact of pregnancy and obesity on influenza virus infection. Influenza Other Respi Viruses Feb 15, 2012. Epub ahead of print.

Sundararajan A, Huan L, Richards KA, Marcelin G, Alam S, Joo H, Yang H, Webby RJ, Topham DJ, Sant AJ, Sangster MY. Host differences in influenza-specific CD4 T cell and B cell responses are modulated by viral strain and route of immunization. PLoS One 7(3):e34377, 2012.

Crossley B, Hietala S, Hunt T, Benjamin G, Martinez M, Darnell D, Rubrum A, Webby R. Pandemic (H1N1) 2009 in captive cheetah. Emerg Infect Dis Feb;18(2):315-7, 2012.

Liu Q, Qiao C, Marjuki H, Bawa B, Ma J, Guillossou S, Webby RJ, Richt JA, Ma W. Combination of PB2 271A and SR polymorphism at positions 590/591 is critical for viral replication and virulence of swine influenza virus. J Virol Jan;86(2):1233-7, 2012.

Wang DJ, Boltz DA, McElhaney J, McCullers JA, Webby RJ, Webster RG. No evidence of a link between influenza vaccines and Guillain-Barre syndrome-associated antiganglioside antibodies.Influenza Other Respi Viruses May;6(3):159-66, 2012.

O'Brien KB, Vogel P, Duan S, Govorkova EA, Webby RJ, McCullers JA, Schultz-Cherry S. Impaired wound healing predisposes obese mice to severe influenza virus infection. J Infect Dis Jan 15;205(2):252-61, 2012.

Ozaki H, Guan Y, Peiris JSM, Webster RG, Webby RJ. Changing patterns of H6 influenza viruses in Hong Kong Poultry Markets. Influenza Res Treat 702092, 2011.

Kayali G, El-Shesheny R, Kutkat MA, Kandeil AM, Mostafa A, Ducatez MF, McKenzie PP, Govorkova EA, Nasraa MH, Webster RG, Webby RJ, Ali MA. Continuing threat of influenza (H5N1) virus circulation in Egypt. Emerg Infect Dis Dec;17(12):2306-8, 2011.

Byarugaba DK, Ducatez MF, Erima B, Mworozi EA, Millard M, Kibuuka H, Lukwago L, Bwogi J, Kaira BB, Mimbe D, Schnabel DC, Krauss S, Darnell D, Webby RJ, Webster RG, Wabwire-Mangen F. Molecular epidemiology of influenza A/H3N2 viruses circulating in Uganda. PLoS One 6(11):e27803, 2011.

Loeb M, Russell ML, Fonseca K, Webby R, Walter SD. Comparison of multiple estimates of efficacy for influenza vaccine. Vaccine Dec 9;30(1):1-4, 2011.

Kayali G, Barbour E, Dbaibo G, Tabet C, Saade M, Shaib HA, Debeauchamp J, Webby RJ. Evidence of infection with H4 and H11 avian influenza viruses among Lebanese chicken growers. PLoS One 6(10):e26818, 2011.

Marcelin G, DuBois R, Rubrum A, Russell CJ, McElhaney JE, Webby RJ. A contributing role for anti-neuraminidase antibodies on immunity to pandemic H1N1 2009 influenza A virus. PLoS One 6(10):e26335, 2011.

Wan XF, Dong L, Lan Y, Long LP, Xu C, Zou S, Li Z, Wen L, Cai Z, Wang W, Li X, Yuan F, Sui H, Zhang Y, Dong J, Sun S, Gao Y, Wang M, Bai T, Yang L, Li D, Yang W, Yu H, Wang S, Feng Z, Wang Y, Guo Y, Webby RJ, Shu Y. Indications that Live Poultry Markets are a Major Source of Human H5N1 Influenza Virus Infection in China. J Virol Dec;85(24):13432-8, 2011.

Cline TD, Karlsson EA, Freiden P, Seufzer BJ, Rehg JE, Webby RJ, Schultz-Cherry S. Increased pathogenicity of a reassortant 2009 pandemic H1N1 influenza virus containing an H5N1 hemagglutinin. J Virol Dec;85(23):12262-70, 2011.

Ma W, Belisle SE, Mosier D, Li X, Stigger-Rosser E, Liu Q, Qiao C, Elder J, Webby R, Katze MG, Richt JA. 2009 Pandemic H1N1 Influenza Virus Causes Disease and Upregulation of Genes Related to Inflammatory and Immune Responses, Cell Death, and Lipid Metabolism in Pigs. J Virol Nov;85(22):11626-37, 2011.

Boon AC, Finkelstein D, Zheng M, Liao G, Allard J, Klumpp K, Webster R, Peltz G, Webby RJ. H5N1 influenza virus pathogenesis in genetically diverse mice is mediated at the level of viral load. Mbio Sep 6;2(5), 2011. PMC3171982.

Ducatez MF, Hause B, Stigger-Rosser E, Darnell D, Corzo C, Juleen K, Simonson R, Brockwell-Staats C, Rubrum A, Wang D, Webb A, Crumpton JC, Lowe J, Gramer M, Webby RJ. Multiple reassortment between pandemic (H1N1) 2009 and endemic influenza viruses in pigs, United States.Emerg Infect Dis Sep;17(9):1624-9, 2011.

Marcelin G, Aldridge JR, Duan S, Ghoneim HE, Rehg J, Marjuki H, Boon AC, McCullers JA, Webby RJ. Fatal Outcome of Pandemic H1N1 2009 Influenza Virus Infection Is Associated with Immunopathology and Impaired Lung Repair, Not Enhanced Viral Burden, in Pregnant Mice. J Virol Nov;85(21):11208-19, 2011. PMC3194964.

Zhu H, Zhou B, Fan X, Lam TT, Wang J, Chen A, Chen X, Chen H, Webster RG, Webby R, Peiris JS, Smith DK, Guan Y. Novel reassortment of eurasian avian-like and pandemic/2009 influenza viruses in Swine: infectious potential for humans. J Virol Oct;85(20):10432-9, 2011. PMC3187487.

Ducatez MF, Cai Z, Peiris M, Guan Y, Ye Z, Wan XF, Webby RJ. Extent of Antigenic Cross-Reactivity among Highly Pathogenic H5N1 Influenza Viruses. J Clin Microbiol Oct;49(10):3531-6, 2011. PMC3187336.

Yen HL, Liang CH, Wu CY, Forrest HL, Ferguson A, Choy KT, Jones J, Wong DD, Cheung PP, Hsu CH, Li OT, Yuen KM, Chan RW, Poon LL, Chan MC, Nicholls JM, Krauss S, Wong CH, Guan Y, Webster RG, Webby RJ, Peiris M. Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets. Proc Natl Acad Sci USA Aug 23;108(34):14264-9, 2011. PMC3161546.

Meroz D, Yoon SW, Ducatez MF, Fabrizio TP, Webby RJ, Hertz T, Ben-Tal N. Putative amino acid determinants of the emergence of the 2009 influenza A (H1N1) virus in the human population. Proc Natl Acad Sci USA Aug 16;108(33):13522-7, 2011. PMC3158228.

Lam TT, Zhu H, Wang J, Smith DK, Holmes EC, Webster RG, Webby R, Peiris JM, Guan Y. Reassortment events among swine influenza A viruses in China: implications for the origin of the 2009 influenza pandemic. J Virol Oct;85(19):10279-85, 2011. PMC3196454.

Yen HL, Forrest H, Cheung P, Wong D, Li O, Krauss S, Ferguson A, Crumpton JC, Jones J, Choy T, Ma E, Poon LL, Smith GJ, Nicholls J, Guan Y, Webster RG, Webby R, Peiris JS. Transmissibility of pandemic H1N1 and genetically related swine influenza viruses in ferrets. Influenza Other Respi Viruses May;5(suppl 1):85-7, 2011.

Last update: September 2019