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Belinda N. Mandrell, PhD, RN, PNP
Belinda N. Mandrell, PhD, RN, PNP

Belinda N. Mandrell, PhD, RN, PNP

Associate Member, St. Jude Faculty

  • Director, Nursing Research Division

Departments

Divisions

Education

BS – University of Tennessee, Knoxville, Tennessee
RN – St. Mary’s Medical Center, School of Nursing, Knoxville, Tennessee
BSN – University of Maryland, Baltimore County, Maryland
MSN – University of Maryland, Baltimore, Maryland
Fellow – National Institutes of Health/National Institute of Nursing Research, Summer Genetics Institute
PhD – University of Tennessee Health Science Center, Memphis, Tennessee

Honors & Awards

  • 2020  American Academy of Nursing Fellow
  • 2017  The Association of Pediatric Hematology/Oncology Nursing, Distinguished Researcher Award
  • 2011  The American Academy of Sleep Medicine Young Investigator Forum
  • 2010  The Association of Pediatric Hematology/Oncology Nursing, Novice Researcher
  • 2006  The Association of Pediatric Hematology/Oncology Nursing, Writing Award
  • 2004  The Association of Pediatric Oncology Nurses, Jean Fergusson Excellence in Pediatric Oncology Nursing Education Award
  • 1998  The American Cancer Society, Lane W. Adams Award for Excellence in Caring
  • 1984  Tennessee Student Nurses Association State Leadership Award
  • 1984  Tennessee Nurses Association Senior Leadership Award

Research Interests

  • Genotype-phenotype association
  • Family history
  • Fatigue
  • Sleep
  • Quality of life patients and family
  • Late effects

Selected Publications

Lubas MM, Mandrell BN, Greene WL, Howell CR, Christensen R, Kimberg CI, Chenghong L, Ness KK, Srivastava DK, Hudson MM, Robison LL, Krull KR, Brinkman TM. A randomized double-blind placebo-controlled trial of the effectiveness of Melatonin on neurocognition and sleep in survivors of childhood cancer. Ped Blood Cancer Jul;68(7):e28988, 2021. doi: 10.1002/pbc.28988. PMID: 33822460

Berry-Carter K, Barnett B, Canavera K, Baker JN, Mandrell BN*. Development of a structured peer mentoring program for support of parents and caregivers of children with cancer. J Pediatr Nurs Jul-Aug 2021;59:131-136, 2021. doi: 10.1016/j.pedn.2021.03.031. PMID: 33878538

Mandrell BN*, Gattuso JS, Pritchard M, Caples M, Howard Sharp KM, Harrison L, Ouma AA, Valdez JM, Johnson LM, Nichols KE. Knowledge is power: Benefits, risks, hopes, and decision-making reported by parents consenting to next-generation sequencing for children and adolescents with cancer. Semin Oncol Nurs 37(3):151167, 2021. doi: 10.1016/j.soncn.2021.151167. PMID: 34127338

Lubas MM, Mandrell BN, Ness KK, Srivastava DK, Ehrhardt MJ, Hudson MM, Robison LL, Krull KR, Brinkman TM. Short sleep duration and physical and psychological health outcomes among adult survivors of childhood cancer. Pediatr Blood Cancer Apr 6:e28988, 2021. doi: 10.1002/pbc.28988. Epub ahead of print. PMID: 33822460

Metzger ML, Link MP, Billett AL, Flerlage J, Lucas JT, Mandrell BN, Ehrhardt MJ, Bhakta N, Yock TI, Friedmann AM, de Alarcon P, Luna-Fineman S, Larsen E, Kaste SC, Shulkin B, Lu Z, Li C, Hinker SM, Donaldson SS, Hudson MM, Krasin MJ. Excellent outcome for pediatric patients with high risk Hodgkin lymphoma treated with brentuximab vedotin and risk-adapted residual mode radiation. J Clin Oncol Apr 7:JCO2003286, 2021. doi: 10.1200/JCO.20.03286. Online ahead of print. PMID: 33826362

Mandrell BN*, LaRosa K, Hancock D, Caples M, Sykes A, Lu Z, Wise MS, Khan RB, Merchant TE, Crabtree VMc. Predictors of narcolepsy and hypersomnia due to medical disorder in pediatric craniopharyngioma. J Neurooncol 148(2):307-316, 2020. doi: 10.1007/s11060-020-03519-3

Crabtree VM, Klages KL, Sykes A, Wise MS, Lu Z, Indelicato D, Merchant TE, Avnet Y, Mandrell BN*. Sensitivity and specificity of the modified Epworth sleepiness scale in children with craniopharyngioma. J Clin Sleep Med 5(10):1487-1493, 2019. doi: 10.5664/jcsm.7982

Sullivan CE, King AR, Holdiness J, Durrell J, Roberts J, Ogg SW, Moreland M, Browne EK, Cartwright C, Crabtree VM, Baker JN, Brown M, Sykes A, Mandrell BN. Reducing compassion fatigue in inpatient pediatric oncology nurses. Oncol Nurs Forum 46(3):338-347, 2019. doi: 10.1188/19.ONF.338-347

Mandrell BN, Withycombe JS. Symptom biomarkers for children receiving treatment for cancer: State of the science.  J Pediatr Oncology Nurses 36(4):280-286, 2019. PMID: 31307320; doi: 10.1177/1043454219859233

Browne E, Moore C, Sykes A, Lu Z, Jeha S, Mandrell BN. Clinical characteristics of intravenous PEG-Asparaginase hypersensitivity reactions in patients undergoing treatment for acute lymphoblastic leukemia.  J Pediatr Oncology Nurses 35(2):103-109, 2018. PMID: 29161979

Mandrell BN, Avent Y, Walker B, Loew M, Tynes BL, Crabtree VM.  In-Home salivary melatonin collection:  Methodology for children and adolescents. Dev Psychobiol 60(1):118-122, 2018. PMID: 29152732

Ringwald-Smith KR, Hobar A, Flowers C, Badgett K, Williams-Hooker R, Roach R, Sykes A, Lu Z, Mackert P, Mandrell BN. Comparison of resting energy expenditure assessment in pediatric oncology patients. Nutr Clin Pract 2018.  Doi.org/10.1002/ncp.10002

Kahn RB, Merchant TE, Sadighi ZS, Crabtree VM, Mercedes SB, Sykes A, Lu Z, Zabrowski J, Simmons A, Clark ME, Merrill SW, Mandrell BN. Prevalence, risk factors, and response to treatment for hypersomnia/narcolepsy in survivors of childhood brain tumors. J Neuro-Oncology 136(2):379-384, 2018. PMID: 29116485

Mandrell BN, Moore C, Crabtree VM. Assessing common sleep disturbances in survivors of childhood cancer. J Nurse Pract 14(4): 245-250, 2018. doi:org/10.1016/j.nurpra.2017.11.009

Donohue C, Bosi J, Sykes A, Zhaohua L, Mandrell BN. Clinical characteristics of oral mucositis in children and adolescents undergoing hematopoietic cell transplant. Oncol Nurs Forum 45(4): 457-462, 2018. doi:10:1188/18.ONF

Broniscer A, Jia, S, Mandrell BN, Hamideh D, Huang J, Onar-Thomas A, Gajjar A, Raimondi S, Tatevossian RG, Steward CF. Phase 1 Trial, pharmacokinetics, and pharmacodynamics of dasatinib combined with crizotinib in children with recurrent or progressive high-grade and diffuse intrinsic pontine glioma. Pediatr Blood Cancer 65(7): e27135, 2018. PMID: 29512900; doi:10.1002/pbc.27035

Graef DM, Crabtree VM, Srivastava DK, Chenghong L, Pritchard M, Hinds P, Mandrell BN.  Sleep and mood during hospitalization for high chemotherapy and hematopoietic rescue in pediatric medulloblastoma.  Psycho-Oncol 27(7):1847-1853, 2018. PMID: 29663636; doi:10.1002/pon.4737

Levine D, Mandrell BN, Sykes A, Pritchard M, Gibson D, Gattuso J, Symons H, Wendler D, Baker JN.  Patients’ and parents’ needs, attitudes, and perceptions about early palliative care integration in pediatric oncology.  JAMA Oncol 3(9):1214-1220, 2017.  PMID:28278329; doi: 10.1001/jamaoncol.2017.0368

Johnson LM, Valdez JM, Quinn E, Sykes A, McGee RB, Nuccio R, Hines-Dowell S, Baker JN, Kesserwan C, Nichols KE, Mandrell BN.  Integrating next generation sequencing into pediatric oncology practice: An assessment of physician confidence and understanding of clinical genomics. Cancer 123(12):2352-2359, 2017. PMID:2819596, doi: 10.1002/cncr.30581

Alderfer MA, Lindell RB, Viadro CI, Zelley K, Valdez J, Mandrell BN, Ford CA, Nichols K.  Should genetic testing be offered for children? The perspectives of adolescents and emerging adults in families with Li-Faumeni Syndrome. J Genet Couns (26(5):1106-1115, 2017.  PMID:28303452, doi: 10.1007/s10897-017-0091-x

Boles JC, Winsor DL, Mandrell BN, Gattuso J, West N, Leigh L, Grissom S. Student/Patient: The school perceptions of children with cancer. Educational Studies 43(5), 2017. doi.org/10.1080/03055698.2017.1312288

Sparrow J, Zhu L, Gajjar A, Mandrell BN, Ness K. Constraint-induced movement therapy for children with brain tumors.  Pediatr Phys Ther 29(1):55-61, 2017. PMID: 27984470

Momani T, Hathaway D, Mandrell BN. Factors affecting health-related quality of life in children undergoing curative treatment for cancer: A review of the literature. J Pediatr Onc Nurs 33(3):228-240, 2016. PMID: 26611756

Grissom S, Boles J, Bailey K, Cantrell K, Kennedy A, Sykes A, Mandrell BN.  Play-based procedural preparation and support intervention for cranial radiation. Supp Care Cancer 24(6):2421-2427, 2016. PMID:26634562

Jacola L, Conklin H, Scoggins M, Ashford J, Merchant T, Mandrell BN, Ogg R, Curtis E, Wise M, Indelicato D, Crabtree V. Investigating the role of hypothalamic tumor involvement in sleep and cognitive outcomes among children treated for craniopharynigioma. J Pediatr Psychol 41(6):610-622, 2016. PMID:27189690

Mandrell BN, Baker J, Levine D, Gattuso J, West N, Sykes A, Gajjar A, Broniscer A. Children with minimal chance for cure: parent proxy of the child’s health-related quality of life and the effect on parental physical and mental health during treatment. J Neuro-Oncol 129(2):373-381, 2016. PMID:27344555

Haugen M, Landier W, Mandrell BN, Sullivan J, Schwartz C, Skeens M, Hockenberry M. Educating families of children newly diagnosed with cancer: Insights of a Delphi panel of expert clinicians from the Children’s Oncology Group. J Pediatr Oncol Nurs 33(6):422-431, 2016. PMID:27268501

Navid F, Herzog C, Sandoval J, Daryani V, Stewart C, Gattuso J, Mandrell BN, Phipps S, Chemaitilly W, Davidoff A, Shulkin B, Jenkins J, Mao S, Wu J, Schiff D, Rao B, Pappo A. Feasibility of pegylated interferon in children and young adults with resected stage III melanoma. Pediatr Blood Cancer 63(7):1207-1213, 2016. PMID:27038395

Momani TG, Mandrell BN, Gattuso JS, West NK, Hinds PS. Children’s perspective on health-related quality of life during active treatment for acute lymphoblastic leukemia:  An advanced content analysis approach. Cancer Nurs 38(1):49-58, 2015. PMID:25075644

Crabtree VM, Rach AM, Schellinger KB, Russell KM, Hammarback T, Mandrell BN. Changes in sleep and fatigue in newly treated pediatric oncology patients. Support Care Cancer 23(2):393-401, 2015. PMID:25112560

Levine DR, Johnson LM, Mandrell BN, Yang J, West NK, Hinds PS, Baker JN. Does Phase I trial enrollment preclude quality end-of-life care? Phase 1 trial enrollment and end-of-life care characteristics in children with cancer. Cancer 121(19):1508-1512, 2015. PMID:25557437

Baker JN, Levine D, Hinds P, Weaver MS, Cunningham MJ, Anghelescu D, Johnson LM, Mandrell BN, Gibson DV, Jones B, Wolfe J, Feudtner C, Freibert S, Carter B, Kane JR. Research priorities in pediatric palliative care. J Pediatr 167(2):467-470, 2015. PMID:26028284

Berger AM, Mooney K, Alvarez-Perez A, Breitbart WS, Mandrell BN, et al. Cancer-related fatigue, Version 2.2015. J Natl Compr Canc Netw 13(8):1012-39, 2015. PMID: 26285247

Last update: February 2022

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