Selected Publications
Naik S, Li Y, Talleur AC, Selukar S, Ashcraft E, Cheng C, Madden RM, Mamcarz E, Qudeimat A, Sharma A, Srinivasan A, Suliman AY, Epperly R, Obeng EA, Velasquez MP, Langfitt D, Schell S, Métais JY, Arnold PY, Hijano DR, Maron G, Merchant TE, Akel S, Leung W, Gottschalk S, Triplett BM. Memory T-cell enriched haploidentical transplantation with NK cell addback results in promising long-term outcomes: a phase II trial. J Hematol Oncol. 2024 Jun 27;17(1):50. doi: 10.1186/s13045-024-01567-0. PMID: 38937803; PMCID: PMC11212178.
Epperly R, Gottschalk S, DeRenzo C. CAR T cells redirected to B7-H3 for pediatric solid tumors: Current status and future perspectives. EJC Paediatr Oncol. 2024 Jun;3:100160. doi: 10.1016/j.ejcped.2024.100160. Epub 2024 Mar 17. PMID: 38957786; PMCID: PMC11218663.
Epperly R, Li Y, Selukar S, Zeng E, Madden R, Mamcarz E, Naik S, Qudeimat A, Sharma A, Talleur A, Dallas MH, Gottschalk S, Srinivasan A, Triplett B. Disease Status and Interval between Hematopoietic Cell Transplantations Predict Outcome of Pediatric Patients Who Undergo Subsequent Transplantation for Relapsed Hematologic Malignancy. Transplant Cell Ther. 2024 May;30(5):526.e1-526.e11. doi: 10.1016/j.jtct.2024.02.016. Epub 2024 Feb 20. PMID: 38387720; PMCID: PMC11056306.
Petgrave Y, Selukar S, Epperly R, Naik S, Santos ND, Triplett BM, Gottschalk S, Bissler J, Talleur AC. Acute kidney injury following treatment with CD19-specific CAR T-cell therapy in children, adolescent, and young adult patients with B-cell acute lymphoblastic leukemia. Pediatr Nephrol. 2024 Aug;39(8):2495-2503. doi: 10.1007/s00467-024-06331-7. Epub 2024 Mar 20. PMID: 38507119; PMCID: PMC11199105.
McNerney KO, Hsieh EM, Shalabi H, Epperly R, Wolters PL, Hill JA, Gardner R, Talleur AC, Shah NN, Rossoff J. INSPIRED Symposium Part 3: Prevention and Management of Pediatric Chimeric Antigen Receptor T Cell-Associated Emergent Toxicities. Transplant Cell Ther. 2024 Jan;30(1):38-55. doi: 10.1016/j.jtct.2023.10.006. Epub 2023 Oct 10. PMID: 37821079; PMCID: PMC10842156.
Epperly R, Giordani VM, Mikkilineni L, Shah NN. Early and Late Toxicities of Chimeric Antigen Receptor T-Cells. Hematol Oncol Clin North Am. 2023 Dec;37(6):1169-1188. doi: 10.1016/j.hoc.2023.05.010. Epub 2023 Jun 21. PMID: 37349152; PMCID: PMC10592597.
Epperly R, Shulkin BL, Bag AK, Cheng C, Inaba H, Lucas JT, Naik S, Triplett BM, Gottschalk S, Talleur AC. CD19 CAR T-cell therapy demonstrates activity against extramedullary disease in pediatric patients with B-ALL. Blood Adv. 2023 Oct 24;7(20):6320-6324. doi: 10.1182/bloodadvances.2023010461. PMID: 37595052; PMCID: PMC10589782.
Levine DR, Epperly R, Collins G, Talleur AC, Mandrell B, Pritchard M, Sarvode Mothi S, Li C, Lu Z, Baker JN. Integration of Palliative Care in Hematopoietic Cell Transplant: Pediatric Patient and Parent Needs and Attitudes. J Pain Symptom Manage. 2023 Sep;66(3):248-257. doi: 10.1016/j.jpainsymman.2023.06.005. Epub 2023 Jun 10. PMID: 37302531.
Pfeiffer T, Li Y, Ashcraft E, Karol SE, Rubnitz JE, Epperly R, Madden R, Mamcarz E, Obeng E, Qudeimat A, Sharma A, Srinivasan A, Suliman A, Talleur AC, Velasquez MP, Gottschalk S, Triplett BM, Naik S. Venetoclax-based therapy as a bridge to allogeneic hematopoietic cell transplantation in children with relapsed/refractory AML. Bone Marrow Transplant. 2023 Mar;58(3):328-331. doi: 10.1038/s41409-022-01877-2. Epub 2022 Nov 29. PMID: 36443431.
Epperly R, Shah NN. Long-term follow-up of CD19-CAR T-cell therapy in children and young adults with B-ALL. Hematology Am Soc Hematol Educ Program. 2023 Dec 8;2023(1):77-83. doi: 10.1182/hematology.2023000422. PMID: 38066902; PMCID: PMC10727115.
Epperly R, Talleur AC, Li Y, Schell S, Tuggle M, Métais JY, Huang S, Pei D, Cheng C, Madden R, Mamcarz E, Naik S, Qudeimat A, Sharma A, Srinivasan A, Suliman A, Gottschalk S, Triplett BM. Sub-myeloablative second transplantations with haploidentical donors and post-transplant cyclophosphamide have limited anti-leukemic effects in pediatric patients. Transplant Cell Ther May 1;28(5):262.e1-262.e10, 2022.
Maron GM, Hijano DR, Epperly R, Su Y, Tang L, Hayden RT, Naik S, Karol SE, Gottschalk S, Triplett BM, Talleur AC. Infectious complications in pediatric, adolescent and young adult patients undergoing CD19-CAR T cell therapy. Front Oncol Mar 9;12:845540, 2022.
Hebbar N, Epperly R, Vaidya A, Thanekar U, Moore SE, Umeda M, Ma J, Patil SL, Langfitt D, Huang S, Cheng C, Klco JM, Gottschalk S, Velasquez MP. CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells. Nat Commun Jan 31;13(1):587, 2022.
Epperly R, Santiago T, Morin C, Patton K, Deyo J, Eshun J, Triplett B, Sharma A. Targeting plasma cells with daratumumab aids in the treatment of post-transplant autoimmune-like hepatitis. Pediatr Blood Cancer Aug;e29290, 2021. doi: 10.1002/pbc.29290
Epperly R, Gottschalk S, Velasquez MP. Harnessing T cells to target pediatric acute myeloid leukemia: CARs, BiTEs, and beyond. Children Feb;7(2), 2020. doi: 10.3390/children7020014
Epperly R, Gottschalk S, Velasquez MP. A bump in the road: How the hostile AML microenvironment affects CAR T cell therapy. Front Oncol Feb;10:262, 2020. doi: 10.3389/fonc.2020.00262
Epperly R, Furman W, Hines M, Santiago T, Li Y, Madden R, Mamcarz E, Cervi D, Federico S, Triplett B, Talleur A. Secondary hemophagocytic syndrome after autologous hematopoietic cell transplant and immune therapy for neuroblastoma. Pediatr Blood Cancer Aug;e27964, 2019. doi: 10.1002/pbc.27964
Close A, Sequeira G, Montano G, Alessi L, McCormick M, Cooper J, Epperly R, Zuckerbraun N. Improving the evaluation and management of abnormal uterine bleeding in female adolescents presenting for emergency care. Pediatr Adolesc Gynecol Apr;32(2):128-134, 2019. doi: 10.1016/j.jpag.2018.11.002
Epperly R, Ozolek J, Soltys K, Cohen D, Goyal R, Friehling E. Treatment of pediatric plasma cell myeloma type post-transplant lymphoproliferative disorder with modern risk-directed therapy. Pediatr Blood Cancer Oct;65(10):e27283, 2018. doi: 10.1002/pbc.2728
Last update: July 2024