Cyrine-Eliana Haidar, BS, PharmD

Cyrine-Eliana Haidar, BS, PharmD

  • Clinical Pharmacogenetics Coordinator
  • Assistant Professor, The University of Tennessee Health Sciences Center, Department of Clinical Pharmacy and Translational Science

Board Certifications

  • BCPS, BCOP

Education

  • Lebanese American University

Post-PharmD Training

  • PGY1 Pharmacy Practice Residency, Hackensack University Medical Center, Hackensack, New Jersey
  • PGY2 Oncology Pharmacy Residency, St. Jude Children’s Research Hospital, Memphis, Tennessee

Focused Area of Practice

  • Clinical Pharmacogenetics

Honors/Awards

  • ASHP Foundation 2012 Pharmacy Literature Award for Innovation in Pharmacy Practice
  • ASHP Foundation 2015 Pharmacy Literature Award for Innovation in Pharmacy Practice

Research Interest

  • Clinical Pharmacogenetics

St. Jude Committee Service

  • Pharmacogenetics Oversight Committee
  • Institutional Review Board
  • Pharmaceutical Department Residency Committee

Pharmacy Organizations/Committee Service

  • American College of Clinical Pharmacy (ACCP)
  • American College of Health System Pharmacists (ASHP)
    • Emerging Sciences Section Advisory Group
    • Council on Therapeutics
  • Children’s Oncology Group (COG)
  • Clinical Pharmacogenetics Implementation Consortium (CPIC)
    • CPIC Informatics
  • Hematology Oncology Pharmacy Association (HOPA)
    • Standards Committee
  • Board of Pharmaceutical Specialties
    • Oncology Council

Selected Publications

Gammal RS, Court MH, Haidar CE, Iwuchukwu OF, Gaur AH, Alvarellos M, Guillemette C, Lennox JL, Whirl-Carrillo M, Brummel SS, Ratain MJ, Klein TE, Schackman BR, Caudle KE, Haas DW. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing. Clin Pharmacol Ther 99(4):363-9, 2016. Epub 2015 Nov 9. PMID: 26417955. PubMed Central PMCID: PMC4785051.

Gammal RS, Crews KR, Haidar CE, Hoffman JM, Baker DK, Barker PJ; Estepp JH, Pei D, Broeckel U, Wang W, Weiss MJ, Relling MV, Hankins J. Leveraging Pharmacogenetics for Safe Codeine Use in Children - Emphasis on Sickle Cell Disease. Pediatrics. 138(1): pii: e20153479, 2016. doi: 10.1542/peds.2015-3479. PMID: 27335380. PubMed Central PMCID: PMC4925073.

Yang W, Wu G, Broeckel U, Smith C, Turner V, Haidar CE, Wang S, Carter R, Karol S, Neale G, Crews K, Yang J, Mullighan C, Downing J, Evans W, Relling M. Comparison of Genome Sequencing and Clinical Genotyping for Pharmacogenes. Clin Pharmacol Ther. 100(4):380-8, 2016. Epub 2016 Aug 18. PubMed PMID:27311679.

Hicks JK, Dunnenberger HM, Gumpper KF, Haidar CE, Hoffman JM. Integrating pharmacogenomics into electronic health records with clinical decision support. Am J Health Syst Pharm. 73(23):1967-76,2016. PubMed PMID:27864204. PubMed Central PMCID:PMC5117634.

Pasternak AL, Crew KR, Caudle KE, Smith C, Pei D, Cheng C, Broeckel U, Gaur AH, Hankins J, Relling MV, Haidar CE. The impact of the UGT1A1*60 allele on bilirubin serum concentrations. Pharmacogenomics.  18(1)5-16, 2017. Epub 2016 Dec 14. PubMed PMID: 27967321.

Luzum J, Pakyz R, Elsey A, Haidar C, Peterson J, Whirl-Carrillo M, Handelman S, Palmer K, Pulley J, Beller M, Schildcrout J, Field J, Weitzel K, Cooper-DeHoff R, Cavallari L, O'Donnell P, Altman R, Pereira N, Ratain M, Roden D, Embi P, Sadee W, Klein T, Johnson J, Relling M, Wang L, Weinshilboum R, Shuldiner A, Freimuth R. The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and metrics of pharmacogenetic implementations across diverse healthcare systems. Clin Pharmacol Ther. 2017 Jan 16. doi: 10.1002/cpt.630. [Epub ahead of print]. PubMed PMID:28090649. PubMed Central PMCID:PMC5511786.

Haidar CE, Hoffman JM, Gammal RS, Relling MV, Crews KR. Development of a Post-Graduate Year 2 Pharmacy Residency in Clinical Pharmacogenetics. Am J Health Syst Pharm. Am J Health Syst Pharm. 74(6):409-15, 2017. PubMed PMID:28274984. PubMed Central PMCID:PMC5499519.

Hicks JK, Crews KR, Flynn P, Haidar CE, Daniels CC, Yang W, Panetta JC, Pei D, Scott JR, Molinelli A, Broeckel U, Bhojwani D, Evans WE, Relling MV. Voriconazole plasma concentrations in immunocompromised pediatric patients vary by CYP2C19 diplotypes. Pharmacogenomics 15(8):1065-1078, 2014.  PubMed PMID:25084200. PubMed Central PMCID: PMC4155516.

Ramsey LB, Johnson SG, Caudle KE, Haidar CE, Voora D, Wilke RA, Maxwell WD, McLeod HL, Krauss RM, Roden DM, Feng Q, Cooper-DeHoff RM, Gong L, Klein TE, Wadelius M, Niemi M. The Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for SLCO1B1 and simvastatin-induced myopathy: 2014 update. Clin Pharmacol Ther 96(4):423-428, 2014. Epub 2014 Jun 11. PMID:24918167. PubMed Central PMCID: PMC4169720.

Relling MV, McDonagh EM, Chang T, Caudle KE, McLeod HL, Haidar CE, Klein T, Luzzatto L. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Rasburicase Therapy in the Context of G6PD Deficiency Genotype. Clin Pharmacol Ther 96(2):169-174, 2014. Epub 2014 May 2. PubMed PMID: 24787449; PubMed Central PMCID: PMC4111801.

Hoffman JM, Haidar CE, Wilkinson MR, Crews KR, Baker DK, Kornegay NM, Yang W, Pui C-H, Reiss UM, Gaur AH, Howard SC, Evans WE, Broeckel U, Relling MV. PG4KDS: A model for the clinical implementation of pre-emptive pharmacogenetics. Am J Med Genet C Semin Med Genet 166C(1):45-55, 2014. Epub 2014 May 11. PubMed PMID: 24619595; PubMed Central PMCID: PMC4056586.

Crews KR, Gaedigk A, Dunnenberger HM, Leeder JS, Klein TE, Caudle KE, Haidar CE, Shen DD, Callaghan JT, Sadhasivam S, Prows CA, Kharasch ED, Skaar TC. Clinical Pharmacogenetics Implementation Consortium guidelines for Cytochrome P450 2D6 genotype and codeine therapy: 2014 update. Clin Pharmacol Ther 95(4):376-382, 2014. Epub 2014 Jan 23. PubMed PMID: 24458010; PubMed Central PMCID: PMC3975215.

Barbarino JM, Haidar CE, Klein TE, Altman RB. PharmGKB summary: very important pharmacogene information for UGT1A1. Pharmacogenet Genomics 24(3):177-183, 2014. PubMed PMID: 24492252; PubMed Central PMCID: PMC4091838.

Bell GC, Crews KR, Wilkinson MR, Haidar CE, Hicks JK, Baker DK, Kornegay NM, Yang W, Cross SJ, Howard SC, Freimuth RR, Evans WE, Broeckel U, Relling MV, Hoffman JM. Development and use of active clinical decision support for preemptive pharmacogenomics. J Am Med Inform Assoc 21(e1):e93-99, 2014. Epub 2013 Aug 26. PubMed PMID: 23978487; PubMed Central PMCID: PMC3957400.

Hicks JK, Crews KR, Hoffman JM, Kornegay NM, Wilkinson MR, Lorier R, Stoddard A, Yang W, Smith C, Fernandez CA, Cross SJ, Haidar C, Baker DK, Howard SC, Evans WE, Broeckel U, Relling MV. A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record. Clin Pharmacol Ther 92(5):563-566, 2012. Epub 2012 Sep 19. PubMed PMID: 22990750; PubMed Central PMCID: PMC3589522.

Perko R, Harreld JH, Helton KJ, Sabin ND, Haidar CE, Wright KD. What goes around comes around? Wernicke encephalopathy and the nationwide shortage of intravenous multivitamins revisited. J Clin Oncol 30(31):e318-e320, 2012.  Epub 2012 Sep 24. PubMed PMID: 23008290; PubMed Central PMCID: PMC3478580.

Haidar C, Jeha S. Drug interactions in childhood cancer. Lancet Oncol 12(1):92-99, 2011. Epub 2010 Sep 22. Review. PubMed PMID: 20869315.

Finks SW, Oliphant CS, Manguso AH, Rogers KC, Bridges G, Haidar CE, Lee KR, Lee M, Lobo B, May AM, Reaves A, Swanson JM, Swims M, Vinson J, Yates ME. Activities of Memphis-area hospitals to meet National Patient Safety Goals for warfarin therapy. Am J Health Syst Pharm 66(24):2179-2188, 2009. PubMed PMID: 19966086.

Last update: January 2018