Pharmaceutical Department Residency Programs

Clinical Pharmacogenomics


St. Jude Children’s Research Hospital offers a 12-month ASHP-accredited specialized (PGY2) Residency in Clinical Pharmacogenomics. 

This program prepares residents to excel in implementing pharmacogenomic testing in clinical practice. The institution’s full integration of an electronic medical record that applies to inpatient and outpatient care, the comprehensive translational research programs, the highly skilled clinical pharmacy specialist team, and the strong laboratory component to the Pharmaceutical Department provides unmatched opportunities for clinical use of pharmacogenetics into patient care. 

The resident will learn, contribute and participate in a dynamic environment with world experts translating laboratory-based discoveries into comprehensive medication management for multiple disease states.

St. Jude runs an institution-wide program to implement pre-emptive pharmacogenomic testing (PG4KDS). The resident will assist in directing the PG4KDS program and provide pharmacogenomic consults in the context of a comprehensive approach to pharmaceutical care integrated into the clinical practice areas: general hematology/oncology, bone marrow transplantation and ambulatory care. Training will be provided in applied pharmacokinetics, infectious diseases, nutrition support, clinical informatics, and advanced pediatric pharmacotherapy. Each resident will work with established clinicians on interdisciplinary teams to deliver personalized pharmacotherapy to pediatric patients with catastrophic diseases.


The resident will design safe and effective patient-centered therapeutic regimens and monitoring plans. In addition, he or she will build pharmacogenomic clinical consults and help develop clinical decision-support based rules for alerting clinicians of high-risk gene-drug pairs to allow for genetically guided drug dosing. The resident will be expected to write a manuscript for publication and participate in patient education, drug information, quality improvement and medication-outcomes activities.

Residents are highly involved in international efforts to implement pharmacogenomics on a broad scale via participation in Clinical Pharmacogenetics Implementation Consortium (CPIC). Upon completion of the program, the resident will have the clinical skills, leadership skills and necessary experience to manage a clinical pharmacogenomics practice, and to implement pharmacogenomic testing in other health-system settings.

Clinical Pharmacogenomic residents learn, contribute and participate in a dynamic environment that consists of professional and technical personnel in both patient care and pharmaceutical research. Along with direct patient care responsibilities, residents will have the opportunity to gain experience in teaching through lectures, in-services, journal club presentations and precepting pharmacy students. A teaching certificate is offered by the University of Tennessee College of Pharmacy. An independent research project will be carried out during the residency, with a presentation of the findings at a national meeting.


Longitudinal Experiences

Research project

The resident will complete a research project and present the results at a national meeting. The project will encompass one of the following areas: laboratory performance characteristics of genotyping techniques, creation of automated pharmacogenomic consults and alerts in the medical record, clinician actions based on point-of-care pharmacogenomic alerts, patient acceptance of pharmacogenomic information or generalizability to other clinical settings.  The resident will use effective written and oral communication to disseminate the research findings.

Educational experiences

Throughout the year, the Clinical Pharmacogenomics resident will provide didactic lectures to pharmacy students and in-services to clinicians on implementation of pharmacogenomics in the clinic. In addition, the resident will present at journal clubs and may participate in the Pharmacogenetics Oversight Committee and other institutional meetings.


Number of Positions


Start Date

July 1

Application Deadline

Monday, January 6, 2020

Learn How to Apply to the Clinical Pharmacogenomics Residency >


Program Director

Kristine R. Crews, PharmD, FCCP, BCPS