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Daniel A. Mulrooney, MD, MS
Daniel A. Mulrooney, MD, MS


BA – University of St. Thomas, St. Paul, Minnesota
MD – Loyola University, Stritch School of Medicine, Chicago, Illinois
MS – University of Minnesota, School of Public Health, Minneapolis, Minnesota

Research Interests

  • Late effects of childhood cancer therapy
  • Cardiovascular outcomes of cancer therapy
  • Transition of care from pediatric to adult medicine
  • Adolescent and young adult oncology

Selected Publications

Cheun YT, Edelmann MN, Mulrooney DA, Green DM, Chemaitilly W, John N, Robison LL, Hudson MM, Krull KR. Uric acid and neurocognitive function in survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only. Cancer Epidemiol Biomarkers Prev 2016 (in press).

Fernandez-Pineda I, Hudson MM, Pappo AS, Bishop MW, Klosky JL, Brinkman TM, Srivastava DK, Neel MD, Rao BN, Davidoff AM, Krull KR, Mulrooney DA, Robison LL, Ness KK. Long-Term functional outcomes and quality of life in adult survivors of childhood extremity sarcomas: a report from the St. Jude Lifetime Cohort Study. J Cancer Surviv 2016 (in press).

Baassiri MJ, Mulrooney DA.At the Heart of Adolescent and Young Adult Cancer Survivorship. J Clin Oncol 34(14):1570-2, 2016.

Boland AM, Gibson TN, Lu L, Kaste SC, DeLany JP, Partin RE, Lanctot JQ, Howell CR, Nelson HH, Chemaitilly W, Pui CH, Robison LL, Mulrooney DA, Hudson MM, Ness KK. Dietary Protein intake and lean mass in survivors of childhood acute lymphoblastic leukemia: a report from the St. Jude Lifetime Cohort Study. Phys Ther Epub ahead of print, 2016.

Mogil RJ, Kaste SC, Ferry RJ, Hudson MM, Mulrooney DA, Howell CR, Partin RE, Srivastava DK, Robison LL, Ness KK. Effect of Low-Magnitude, High-Frequency Mechanical Stimulation on BMD Among Young Childhood Cancer Survivors: A Randomized Clinical Trial. JAMA Oncol Epub ahead of print, 2016.

Chow E, Anderson L, Baker KS, Bhatia S, Guilcher GMT, Huang JT, Pelletier W, Perkins JL, Rivard LS, Schechter T, Shah AJ, Wilson KD, Wong K, Grewal S, Armenian S, Meacham LR, Mulrooney DA, Castellino SM. Late Effects Surveillance Recommendations among Survivors of childhood Hematopoietic Cell Transplantation: A Children’s Oncology Group Report. Biol Blood Marrow Transplant 22(5):782-95, 2016.

Mulrooney DA, Armstrong GT, Huang S, Ness KK, Ehrhardt MJ, Joshi VM, Plana JC, Soliman EZ, Green DM, Srivastava DK, Santucci A, Krasin MJ, Robison LL,  Hudson MM. Cardiac Outcomes in Adult Survivors of Childhood Cancer Exposed to Cardiotoxic Therapy: A Cross-Sectional study from the St. Jude Lifetime Cohort. Ann Intern Med 164(2):93-101, 2016.

Schempp A, Lee J, Kearney S, Mulrooney DA, Smith AR. Iron Overload in Survivors of Childhood Cancer. J Pediatr Hematol Oncol 38(1):27-31, 2015.

Edelmann MN, Daryani VM, Bishop MW, Liu W, Brinkman TM, Stewart CF, Mulrooney DA, Kimberg C, Ness KK, Cheung YT, Srivastava DK, Robison LL, Hudson MM, Krull KR. Neurocognitive and Patient-Reported Outcomes in Adult Survivors of Childhood Osteosarcoma. JAMA Oncol 2(2):201-8, 2015.

Mulrooney DA, Duprez D. Caring for cancer survivors – more than just checking the blood pressure and measuring the ejection fraction. Future Cardiol 11(4):371-5, 2015.

Ness KK, DeLany JP, Kaste SC, Mulrooney DA, Pui CH, Chemaitilly W, Karlage RE, Lanctot J, Howell CR , Lu L, Srivastava DK, Robison LL, Hudson MM. Energy balance and fitness in adult survivors of childhood acute lymphoblastic leukemia. Blood 125(22):3411-9, 2015.

Armstrong GT, Joshi VM, Ness KK, Marwick TH, Zhang N, Srivastava DK, Griffin B, Grimm R, Thomas JT, Phelan D, Collier P, Krull K, Mulrooney DA, Green DM, Hudson MM, Robison LL, Plana JC.  Comprehensive Echocardiographic Detection of Treatment-related Cardiac Dysfunction in Adult Survivors of Childhood Cancer: Results from the St. Jude Lifetime Cohort Study. J Am Coll Cardiol 65(23):2511-22, 2015.

Ehrhardt MJ, Mulrooney DA. Metabolic syndrome in adult survivors of childhood cancer: the intersection of oncology, endocrinology, and cardiology. Commentary, Lancet Diabetes Endocrinol 3(7):494-6, 2015.

Hudson MM, Oeffinger KC, Jones KE, Brinkman TM, Krull KR, Mulrooney DA, Mertens AC, Castellino SM, Casillas JN, Gurney JG, Nathan PC, Leisenring WM, Robison LL, Ness KK. Age-Dependent Changes in Health Status in the childhood Cancer Survivor Cohort. J Clin Oncol 33(5):479-91, 2015.

Chow EJ, Chen Y, Kremer LC, Breslow NE, Hudson MM, Armstrong GT, Border WL, Feijen EAM, Green DM, Meacham LR, Meeske KA, Mulrooney DA, Ness KK, Oeffinger KC, Sklar CA, Stovall M, Van der Pal HJ, Weathers RE, Robison LL, Yasui Y. Individual prediction of heart failure among childhood cancer survivors. J Clin Oncol 33(5):394-402, 2015.

Blair CK, Kelly AS, Steinberger J, Eberly LE, Napurski C, Robien K, Neglia JP, Mulrooney DA, Ross JA. Feasibility and preliminary efficacy of the effects of flavonoid-rich purple grape juice on the vascular health of childhood cancer survivors: a randomized controlled crossover trial. Pediatr Blood Cancer 61(12):2290-6, 2014.

Mulrooney DA, Nunnery S, Armstrong GT, Ness KK, Srivastava DK, Donovan D, Kurt BA, Metzger ML, Krasin MJ, Joshi V, Duran JB, Robison LL, Hudson MM, Flamm SD. Coronary artery disease detected by coronary computed tomographic angiography in adult survivors of childhood Hodgkin lymphoma. Cancer 120(22):3536-44, 2014.

Smith WA, Li C, Nottage K, Mulrooney DA, Armstrong GT, Lanctot JQ, Chemaitilly W, Laver JH, Srivastava DK, Robison LL, Ness KK. Lifestyle and metabolic syndrome in adult survivors of childhood cancer: a report from the St. Jude Lifetime Cohort Study. Cancer 120(17):2742-50, 2014.    

Dietz AC, Sivanandam S, Konety S, Kaufman C, Gage R, Kelly A, Neglia J, Mulrooney DA. Evaluation of traditional and novel measures of cardiac function to detect anthracycline induced cardiotoxicity in survivors of childhood cancer. J of Cancer Survivorship 8(2):183-9, 2014.  

Ness KK, Krull KR, Jones KE, Mulrooney DA, Armstrong GT, Green DM, Chemaitilly W, Smith WA, Wilson CL, Sklar CA, Shelton K, Srivastava DK, Ali S, Robison LL, Hudson MM. Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer:  a report from the St. Jude Lifetime Cohort Study. J Clin Oncol 31(36):4496-503, 2013.

Armstrong GT, Oeffinger KC, Chen Y, Kawashima T, Yasui Y, Leisenring W, Stovall M, Chow EJ, Sklar CA, Mulrooney DA, Mertens AC, Border W, Durand JB, Robison LL, Meacham LR. Modifiable risk factors and major cardiac events among adult survivors of childhood cancer. J Clin Oncol 31(29):3673-80, 2013.  

Mulrooney DA, Ness KK, Huang S, Solovey A, Hebbel RP, Neaton JD, Clohisy DR, Kelly AS, Neglia JP.  Pilot study of vascular health in survivors of osteosarcoma. Pediatr Blood Cancer 60(10):1703-8, 2013.

Hudson MM, Ness KK, Gurney JG, Mulrooney DA, Chemaitilly W, Krull KR, Green DM, Armstrong GT, Nottage KA, Jones KE, Sklar CA, Srivastava DK, Robison LL. Clinical ascertainment of health outcomes among adults treated for childhood cancer. JAMA.309(22):2371-81, 2013.

Hoffman M, Mulrooney DA[1] [Co-First Author], Steinberger J, Lee J, Baker KS, Ness KK.  Deficits of physical function among young childhood cancer survivors. J Clin Oncol 31(22):2799-805, 2013.

Marina N, Hudson MM, Jones KE, Mulrooney DA, Avedian R, Donaldson SS, Popat R, West DW, Fisher P, Leisenring W, Stovall M, Robison LL, Ness KK. Changes in health status among aging survivors of pediatric upper and lower extremity sarcoma: a report from the Childhood Cancer Survivor Study (CCSS). Arch Phys Med Rehabil 94(6):1062-73, 2013.

Show More

Mulrooney DA, Blaes AH, Duprez D. Vascular injury in cancer survivors. J Cardiovasc Transl Res 5(3):287-95, 2012.

Mulrooney DA, Ness KK, Solovey A, Hebbel RP, Neaton JD, Peterson BA, Lee CKK, Kelly AS, Neglia JP. Pilot Study of Vascular Health in Survivors of Hodgkin Lymphoma. Pediatr Blood Cancer 59(2):285-9, 2012.

Steinberger J, Sinaiko AR, Kelly AS, Leisenring WM, Steffen LM, Goodman P, Mulrooney DA, Dietz AC, Moran A, Perkins JL, Baker KS. Cardiovascular risk and insulin resistance in childhood cancer survivors. J Pediatr 160(3):494-9, 2012.

Dietz, AC, Mulrooney DA. Life beyond the disease: relationships, parenting, and quality of life among survivors of childhood cancer. Haematologica 96(5):643-645, 2011.

Robien K, Strayer LG, Majhail N, Lazovich D, Baker KS, Smith AR, Mulrooney DA, Burns LJ. Vitamin D status among long-term survivors of hematopoietic cell transplantation. Bone Marrow Transplant 46(11):1472-9, 2011. PMID: 21243026.

Clanton NR, Klosky JL, Li C, Jain N, Srivastava DK, Mulrooney D, Zeltzer L, Stovall M, Robison LL, Krull KR. Fatigue, vitality, sleep and neurocognitive functioning in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer 117(11):2559-68, 2011. PMID: 21484777.

Blaes AH, Lindgren B, Mulrooney DA, Wilson L, Cho LC. Pathologic femur fractures after limb-sparing treatment of soft-tissue sarcomas. J Cancer Surviv 4(4):399-404, 2010. PMID: 20827514.

McClune BL, Polgreen LE, Burmeister LA, Blaes AH, Mulrooney DA, Burns LJ, Majhail NS. Screening, prevention and management of osteoporosis and bone loss in adult and pediatric hematopoietic cell transplant recipients. Bone Marrow Transplant 46(1):1-9, 2011. PMID: 20729922.

McAvoy S, Baker SK, Mulrooney DA, Blaes A, Arora M, Burns LJ, Majhail NS. Corticosteroid dose as a risk factor for avascular necrosis of the bone after hematopoietic cell transplantation. Biol Blood Marrow Transplant 16(9):1231-1236, 2010.

Mulrooney DA, Yeazel MW, Kawashima T, Mertens AC, Mitby P, Stovall M, Donaldson SS, Green DM, Sklar CA, Robison LL, Leisenring WM. Cardiac Outcomes in a cohort of adult survivors of childhood and adolescent cancer: Retrospective analysis of the Childhood Cancer Survivor Study cohort. BMJ 339:b4606, 2009. PMID: 19996459.

Majhail NS, Challa TR, Mulrooney DA, Baker KS, Burns LJ. Hypertension and diabetes mellitus in adult and pediatric survivors of allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 15(9):1100-1107, 2009. PMID: 19660723.

Diller L, Chow EJ, Gurney JG, Hudson MM, Kadin-Lottick N, Kawashima T, Leisenring WM, Meacham LR, Mertens AC, Mulrooney DA, Oeffinger KC, Packer RJ, Robison LL, Sklar CA. Chronic disease in the childhood cancer survivor study cohort: A review of published findings. J Clin Oncol 27(14):2339-2355, 2009. PMID: 19364955.

Hudson MM, Mulrooney DA, Bowers DC, Sklar CA, Green DM, Donaldson SS, Oeffinger KC, Neglia JP, Meadows AT, Robinson LL. High-risk populations identified in childhood cancer survivor study investigations: Implications for risk-based surveillance. J Clin Oncol 27(14):2405-2414, 2009. PMID: 19289611.

Mulrooney DA, Neglia JP, Hudson MM. Caring for adult survivors of childhood cancer. Curr Treat Options Oncol 9(1):51-66, 2008.

Nandagopal R, Laverdière C, Mulrooney DA, Hudson MM, Meacham L. Endocrine late effects of childhood cancer therapy: A report from the Children's Oncology Group. Hormone Res 69:65-74, 2008.

Mulrooney DA, Dover DC, Yutaka Y, Ness KK, Mertens AC, Neglia JP, Sklar CA, Robison LL, Davies SM. Twenty years of follow-up among survivors of childhood and young adult acute myeloid leukemia: A report from the Childhood Cancer Survivor Study. Cancer 112(9):2071-2079, 2008. PMID: 18327823.

Mulrooney DA, Ness KK, Neglia JP, Whitton J, Green DM, Zeltzer LK, Robison LL, Mertens AC. Fatigue and Sleep Disturbance in Adult Survivors of Childhood Cancer: A report from the Childhood Cancer Survivor Study (CCSS). Sleep 31(2):271-281, 2008. PMID: 18274275.

Ness KK, Gurney JG, Zeltzer LK, Leisenring W, Mulrooney DA, Nathan PC, Robison LL, Mertens AC. The impact of limitations in physical, executive, and emotional function on health-related quality of life among adult survivors of childhood cancer: A report from the Childhood Cancer Survivors Study. Arch Phys Med Rehabil 89(1):128-136, 2008.

Nunez SB, Mulrooney DA, Laverdiere C. Hudson MM. Risk-based health monitoring of childhood cancer survivors: A report from the Children’s Oncology Group. Curr Oncol Rep 9(6):440-452, 2007.

Mulrooney DA, Davies SM, Walk D, Charnas LR. Late occurrence of chronic immune-mediated axonal polyneuropathy following bone marrow transplant for juvenile-onset alpha-mannosidosis.Bone Marrow Transplant 32(9):953-955, 2003.

Mulrooney DA, Carpenter B, Georgieff M, Angel C, Hunter D, Foker J, Steiner M. Hepatic mesenchymal hamartoma in a neonate: A case report and review of the literature. J Pediatr Hematol Oncol 2(5):316-317, 2001.

Last update: June 2016