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Yutaka Yasui, PhD
Yutaka Yasui, PhD

Education

BEng - School of Engineering, Kyoto University, Kyoto, Japan
PhD - School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland

Honors & Awards

  • 2005-2015  Canada Research Chair in Biostatistics and Epidemiologic Methods, Canada Research Chair Program
  • 2006-2013  Health Senior Scholar Award, Alberta Heritage Foundation for Medical Research
  • 2012-2013  Killam Annual Professor Award, Research, Teaching and Service, University of Alberta
  • 2007, 2009  Teaching Award of Excellence, Public Health Sciences Student Association, School of Public Health, University of Alberta
  • 1995  A.M.T.R.A. (Advising, Mentoring, and Teaching Recognition Award) from The Student Assembly, School of Hygiene and Public Health, Johns Hopkins University
  • 1994  Faculty Award (for excellence in teaching/advising) from Student Coordinating Committee,   Department of Health Policy and Management, School of Hygiene and Public Health, Johns Hopkins University

Research Interests

  • Genetic Epidemiology
  • Cancer Survivorship
  • Statistical Learning from Large Biological Data

Current Research

  • Late Effects Prediction using Clinical Phenotypes and Whole Genome Sequencing (Principal Investigator)
  • Childhood Cancer Survivor Study (Epidemiology/Biostatistics Working Group Chair, Executive Committee Member)
  • Improving Treatment of Cardiovascular Risk Factors in Childhood Cancer Survivors (Co-Investigator)
  • Therapy-related Leukemia Following Autologous Transplantation for Lymphoma (Co-Investigator)
  • Cerebrospinal Fluid Biomarkers of Long-Term Neurocognitive and Brain Imaging Adverse Outcomes in Survivors of Childhood Lymphoblastic Leukemia Treated with Chemotherapy (Co-Investigator)

Selected Publications

Full publications list

Im C, Qin N, Wang Z, Qiu W, Howell CR, Sapkota Y, Moon W, Chemaitilly W, Gibson TM, Mulrooney DA, Ness KK, Wilson CL, Morton LM, Armstrong GT, Bhatia S, Zhang J, Hudson MM, Robison LL, Yasui Y. Generalizability of "GWAS Hits" in Clinical Populations: Lessons from Childhood Cancer Survivors. Am J Hum Genet Oct 1;107(4):636-653, 2020. PMID: 32946765. Role: Senior author

Sapkota Y, Wilson CL, Zaidi AK, Moon W, Fon Tacer K, Lu L, Liu Q, Baedke J, Dhaduk R, Wang Z, Chemaitilly W, Krasin MJ, Berry FB, Zhang J, Hudson MM, Robison LL, Green DM, Yasui Y. A novel locus predicts spermatogenic recovery among childhood cancer survivors exposed to alkylating agents. Cancer Res Sep 1;80(17):3755-3764, 2020. PMID: 32554749. Role: Senior author

Chen Y, Chow EJ, Oeffinger KC, Border WL, Leisenring WM, Meacham LR, Mulrooney DA, Sklar CA, Stovall M, Robison LL, Armstrong GT, Yasui Y. Traditional cardiovascular risk factors and individual prediction of cardiovascular events in childhood cancer survivors. J Natl Cancer Ins 112(3):256-265, 2020. PMID: 31161223. Role: Senior author

Yoneoka D, Im C, Yasui Y. Parallel repulsive logic regression with biological adjacency.  Biostatistics 21(4):825-844, 2020. PMID: 31030217. Role: Senior author

Brooke RJ, Im C, Wilson CL, Krasin MJ, Liu Q, Li Z, Sapkota Y, Moon W, Morton LM, Wu G, Wang Z, Chen W, Howell RM, Armstrong GT, Bhatia S, Mostoufi-Moab S, Seidel K, Chanock SJ, Zhang J, Green DM, Sklar CA, Hudson MM, Robison LL, Chemaitilly W, Yasui Y. A high-risk haplotype for premature menopause in childhood cancer survivors exposed to gonadotoxic therapy. J Natl Cancer Inst Aug 1;110(8):895-904, 2018. PMID: 29432556. Role: Senior author

Im C, Ness KK, Kaste SC, Chemaitilly W, Moon W, Sapkota Y, Brooke RJ, Hudson MM, Robison LL, Yasui Y, Wilson CL. Genome-wide search for higher order epistasis as modifiers of treatment effects on bone mineral density in childhood cancer survivors. Eur J Hum Genet Feb;26(2):275-286, 2018. PMID: 29348692.

Bhakta N, Liu Q, Ness KK, Baassiri M, Eissa H, Yeo F, Chemaitilly W, Ehrhardt  MJ, Bass J, Bishop MW, Shelton K, Lu L, Huang S, Li Z, Caron E, Lanctot J, Howell C, Folse T, Joshi V, Green DM, Mulrooney DA, Armstrong GT, Krull KR, Brinkman TM, Khan RB, Srivastava DK, Hudson MM, Yasui Y, Robison LL. The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE). Lancet Dec 9;390(10112):2569-2582, 2017. PMID: 28890157.

Turcotte LM, Liu Q, Yasui Y, Arnold MA, Hammond S, Howell RM, Smith SA, Weathers RE, Henderson TO, Gibson TM, Leisenring W, Armstrong GT, Robison LL, Neglia JP. Temporal Trends in Treatment and Subsequent Neoplasm Risk Among 5-Year Survivors of Childhood Cancer, 1970-2015. JAMA Feb 28;317(8):814-824, 2017. PMID: 28245323.

Armstrong GT, Chen Y, Yasui Y, Leisenring W, Gibson TM, Mertens AC, Stovall M, Oeffinger KC, Bhatia S, Krull KR, Nathan PC, Neglia JP, Green DM, Hudson MM, Robison LL. Reduction in late mortality among 5-year survivors of childhood cancer. N Engl J Med Mar 3;374(9):833-842, 2016. PMID: 26761625.

Chemaitilly W, Li Z, Krasin MJ, Brooke RJ, Wilson CL, Green DM, Klosky JL, Barnes N, Clark KL, Farr JB, Fernandez-Pineda I, Bishop MW, Metzger M, Pui CH, Kaste SC, Ness KK, Srivastava DK, Robison LL, Hudson MM, Yasui Y, Sklar CA. Premature Ovarian Insufficiency in Childhood Cancer Survivors: A Report From the St. Jude Lifetime Cohort. J Clin Endocrinol Metab Jul 1;102(7):2242-2250, 2017. PubMed PMID: 28368472.

Bhakta N, Liu Q, Yeo F, Baassiri M, Ehrhardt MJ, Srivastava DK, Metzger ML, Krasin MJ, Ness KK, Hudson MM, Yasui Y, Robison LL. Cumulative burden of cardiovascular morbidity in paediatric, adolescent, and young adult survivors of Hodgkin's lymphoma: an analysis from the St Jude Lifetime Cohort Study. Lancet Oncol Sep;17(9):1325-1334, 2016. PMID: 27470081.

Wang L, Bhatia S, Gomez SL, Yasui Y. Differential inequality trends over time in survival among U.S. children with acute lymphoblastic leukemia by race/ethnicity, age at diagnosis, and sex. Cancer Epidemiol Biomarkers Prev Nov;24(11):1781-1788, 2015. PMID: 26377194. Role: Senior author

Sharafeldin N, Slattery ML, Liu Q, Franco-Villalobos C, Caan BJ, Potter JD, Yasui Y. A Candidate-Pathway Approach to Identify Gene-Environment Interactions: Analyses of Colon Cancer Risk and Survival. J Natl Cancer Inst Sep;107(9), 2015. PMID: 26072521. Role: Senior author

Dong H, Robison LL, Leisenring WM, Martin LJ, Armstrong GT, Yasui Y. Estimating the burden of recurrent events in the presence of competing risks: The method of mean cumulative count. Am J Epidemiol 181(7):532-540, 2015. PMID: 25693770. Role: Senior author

Chow EJ, Chen Y, Kremer LC, Breslow NE, Hudson MM, Armstrong GT, Border WL, Feijen EA, Green DM, Meacham LR, Meeske KA, Mulrooney DA, Ness KK, Oeffinger KC, Sklar CA, Stovall M, van der Pal HJ, Weathers RE, Robison LL, Yasui Y. Individual prediction of heart failure among childhood cancer survivors. J Clin Oncol 33(5):394-402, 2015. PMID: 25287823. Role: Senior author

Last update: December 2022

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