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Comprehensive Teaching Course on Bone Marrow Failure and Predisposition to Hematopoietic Malignancies


for Physicians, Advanced Practice Providers, and Genetic Counselors

BMF MDS Program logo
St. Jude Global logo

Online curriculum starting Summer 2021

Program Synopsis

Bone marrow failure (BMF) and predisposition to hematopoietic malignancies are a group of rare disorders with at least 150 genes known to be implicated in their etiology. Being rare disorders, evidence-based knowledge is limited and the diagnostic workup, clinical practice decisions as well as surveillance relies on expert knowledge gathered in large academic centers. Patient outcomes vary depending on how they are diagnosed and where they are treated. There is a need for improved and systematic education about these entities, given the limited access to specialized diagnostic tests as well therapies resulting in inferior patient outcomes.

Currently, there is no known published curriculum to teach physicians, advanced practice providers, or genetic counselors about these conditions.

Based on a needs assessment survey that we performed in 2019, we have developed a systematic curriculum on BMF and predisposition to hematopoietic malignancies, with the goal to increase competency in providing safe and optimal care for these patients.

Learning Goals

Create a systematic teaching course to teach BMF/ Heme malignancy predisposition to:

  • Pediatric and adult hematology/oncology physicians (U.S. and worldwide) to improve clinical management
  • Advanced practice providers in the U.S. to improve clinical management
  • Genetic counselors certified via the American Board of Genetic Counselors or other national organization to improve diagnostic workup and counseling

Target Audience 

  • Hematology/Oncology Fellows (Physicians)
  • Advanced Practice Providers (Nurse Practitioners, Physician Assistants)
  • Genetic Counselors


  • Aplastic Anemia
  • Pediatric MDS and Juvenile Myelomonocytic Leukemia
  • Diamond Blackfan Anemia
  • Fanconi Anemia
  • Telomere Biology Disorders (Dyskeratosis Congenita)
  • Severe Congenital Neutropenia and Shwachman Diamond Syndrome
  • GATA2 Deficiency and SAMD9/9L Disorders
  • Other syndromes predisposing to MDS/AML (RUNX1, DDX41, and others)
  • Other syndromes predisposing to BMF (MECOM, DNAJC21, ERCC6L2, and others)
  • Clonal Hematopoiesis of Indeterminate Potential 
  • Predisposition to Lymphatic Malignancies (TP53 and others)

Curriculum Structure / Time Commitment

  • Online Curriculum (April 2021 – September 2021)
    • 14 two-hour long interactive seminars
    • Online assignments with discussion (1 hour preparation time is required for each module)
  • In-Person Curriculum
    • Two-day conference (October 1-2, 2021)

Application Process and Costs

  • The application portal will open in November/December 2020, and the application deadline will be February 2021.
  • Because our goal is to provide individual mentorship, the space will be limited
  • We will provide a number of stipends to cover the full cost of the course
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  1. Portrait of Michael Terao

    Michael Terao, MD
    (formerly of St. Jude)
    Department of Pediatric Hematology/Oncology
    Medstar Georgetown University Hospital

    Portrait of Sara Lewis

    Sara Lewis, MS
    Genetic Counselor III
    Department of Hematology
    St. Jude Children's Research Hospital

    Portrait of Sarah Bannon

    Sarah Bannon, MS, CGC
    Senior Genetic Counselor
    Department of Clinical Cancer Genetics
    MD Anderson Cancer Center

  2. Information is forthcoming.

  3. Information is forthcoming.